Highly versatile, two-color setup for high-order harmonic generation using spatial light modulators.

We present a novel, interferometric, two-color, high-order harmonic generation setup based on a turn-key Ytterbium-doped femtosecond laser source and its second harmonic. Each interferometer arm contains a spatial light modulator with individual capabilities to manipulate the spatial beam profiles and to stabilize the relative delay between the fundamental and the second harmonic. In addition, separate control of the relative power and focusing geometries of the two color beams is implemented to conveniently perform automated scans of multiple parameters. A live diagnostics system gives continuous information during ongoing measurements.

Cálculo de la Edad Biológica en el Tratamiento Antiaging / Biologic Age Measurement for Antiaging therapies

Los autores presentan una nueva fórmula para contrastar la mejoría en el tratamiento antienvejecimiento, partiendo de un test de anamnesis y modificándolo según un factor de corrección de década, otro basado en el estrés oxidativo y tres factores importantes dentro de las costumbres de nuestro país como son el tabaco, el alcohol y el colesterol de baja densidad de lipoproteínas (AU)

The authors present a new formula to evaluare the improvernent after an antiaging treatment. lt is based on an anamnesis test and modified by a decade correction oxidative factor and three factors irnportant in our culture such as smoking, alcohol and colesterol of low density lipoproteis (AU)

Protocolo Médico en la Terapia del Antienvejecimiento. La Importancia de los Radicales libres / Medical Protocol in Antiaging therapy. Importance of Free Radicals

En este trabajo presentamos las teorías actuales del envejecimiento dando especial importancia al efecto de los radicales libres y las causas que los aumentan que pueden estar a nivel mental, dietético y hormonal. Exponemos los tratamientos basados en ejercicio físico, control del estrés y medicación (AU)

In this paper we present the actual theories for antiaging, specially on behalf the effect of free radicals and causes that increase their presence such as mental, diet and hormone. We also explain the treatment based on physical activity, stress control and medication (AU)

The First Synthesis of Organic Diselenolates: Application to the Synthesis of Diorganyl Diselenides.

The addition of elemental selenium to organolithium compounds 1 or organic selenates 2 gives organic diselenolates 3. The reactions proceed by the insertion of two selenium atoms into the carbon-metal bonds or of one selenium atom into a selenolate. Evidence for the existence of n-butyldisilenol has also been obtained.

Artificial neural networks for multicomponent kinetic determinations.

An artificial neural network (ANN) procedure that uses the scores of a principal component model as input data was tested for calibration in the resolution of binary mixtures from kinetic measurements. The results thus obtained are compared with those provided by partial least-squares (PLS) regression and principal component regression (PCR). The ANN was first applied to simulated single wavelength kinetic curves. The effect of experimental variability was considered by assuming rate constants to fit a normal distribution curve. An amount of instrumental noise was also added to the simulated curves. Both linear and nonlinear systems were tested. Non-linearity was assumed to result from interactions between analytes and modeled by introducing a multiplicative term in the rate equation. The results provided by the three methods on linear systems were comparable; in the presence of interactions between analytes, however, the ANN method clearly outperformed the other two. The ANN method was also used to resolve mixtures of Fe(III), Co(II), and Zn(II) by displacement from their EGTA complexes with 4-(2-pyridylazo)resorcinol (PAR) using a stopped-flow injection assembly including a diode array detector. Preliminary experiments revealed the Co(II) and Zn(II) displacement reactions to be pseudo-first-order and that of Fe(III) to be a multistep process that departed from the linear behavior of the other two. Again, the results obtained with ANN were better than those provided by PCR and PLS.

Mechanism of action of somatostatin.

The chain of events leading to the manifestation of the biological action of somatostatin are described. Internalization is mediated by cytoskeletal proteins in the presence of calmodulin. Transduction of the somatostatin message at the membrane level takes place through inhibition of cyclic AMP accumulation and blockade of cytosol calcium increases. The influence of central and peripheral factors upon these processes is discussed and the importance of the Ni/Ns components is stressed. Thus, somatostatin also suppresses phosphoinositide turnover and stimulates soluble phosphodiesterase, thus reinforcing its negative effect on cyclase generation.

Far-infrared laser lines in vinyl fluoride optically pumped by a CO(2) laser near 10 microm.

Sixty-two new emission lines in the far infrared have been observed in vinyl fluoride optically pumped in a metallicwaveguide resonator by a CO(2) laser. The emission spectrum for this molecule now covers the 2.52-mm-142-microm wavelength range.

Continuous-wave Stark far-infrared lasing lines in (15)NH(3) optically pumped by a CO(2) or N(2)O laser.

We report preliminary results of a systematic research of far-infrared (FIR) emissions in (15)NH(3) by Stark-tuning the infrared-pumped transitions to the CO(2) or N(2)O laser lines; 28 new FIR lasing lines have been detected for static-electric fields up to 62 kV/cm.