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Clin Neuropsychol ; 24(5): 827-40, 2010.
Artículo en Inglés | MEDLINE | ID: mdl-20336580

RESUMEN

Schizencephaly is a rare neuromigrational/organizational disorder characterized by the development of cerebral clefts, which are typically associated with neurological sequelae including seizures, motor disturbances, and cognitive dysfunction. Although there are multiple case reports of schizencephaly and associated neurological sequelae, primarily in children, the literature regarding neuropsychological manifestations of schizencephaly is limited. This article reviews the case of a woman diagnosed with bilateral schizencephaly at age 29. Neuropsychological testing revealed intact intelligence and memory functioning. However, impairments were noted in attention, executive functioning, expressive language skills, visual-spatial abilities, and bilateral manual motor skills, all of which were adversely impacting her functional abilities (e.g., ability to be gainfully employed). Given the potential variability in deficits associated with schizencephaly, this case demonstrates the utility of neuropsychological evaluation for understanding cognitive and functional consequences of bilateral schizencephaly.


Asunto(s)
Encéfalo/anomalías , Encéfalo/fisiopatología , Malformaciones del Desarrollo Cortical/diagnóstico , Malformaciones del Desarrollo Cortical/fisiopatología , Adulto , Femenino , Humanos , Imagen por Resonancia Magnética , Malformaciones del Desarrollo Cortical del Grupo II/diagnóstico , Malformaciones del Desarrollo Cortical del Grupo II/fisiopatología , Pruebas Neuropsicológicas
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