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1.
J Biomed Phys Eng ; 6(2): 81-94, 2016 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-27672628

RESUMEN

BACKGROUND: Epilepsy is a severe disorder of the central nervous system that predisposes the person to recurrent seizures. Fifty million people worldwide suffer from epilepsy; after Alzheimer's and stroke, it is the third widespread nervous disorder. OBJECTIVE: In this paper, an algorithm to detect the onset of epileptic seizures based on the analysis of brain electrical signals (EEG) has been proposed. 844 hours of EEG were recorded form 23 pediatric patients consecutively with 163 occurrences of seizures. Signals had been collected from Children's Hospital Boston with a sampling frequency of 256 Hz through 18 channels in order to assess epilepsy surgery. By selecting effective features from seizure and non-seizure signals of each individual and putting them into two categories, the proposed algorithm detects the onset of seizures quickly and with high sensitivity. METHOD: In this algorithm, L-sec epochs of signals are displayed in form of a third-order tensor in spatial, spectral and temporal spaces by applying wavelet transform. Then, after applying general tensor discriminant analysis (GTDA) on tensors and calculating mapping matrix, feature vectors are extracted. GTDA increases the sensitivity of the algorithm by storing data without deleting them. Finally, K-Nearest neighbors (KNN) is used to classify the selected features. RESULTS: The results of simulating algorithm on algorithm standard dataset shows that the algorithm is capable of detecting 98 percent of seizures with an average delay of 4.7 seconds and the average error rate detection of three errors in 24 hours. CONCLUSION: Today, the lack of an automated system to detect or predict the seizure onset is strongly felt.

2.
J Biomed Phys Eng ; 3(3): 93-104, 2013 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-25505753

RESUMEN

BACKGROUND: Breast cancer is currently one of the leading causes of death among women worldwide. The diagnosis and separation of cancerous tumors in mammographic images require accuracy, experience and time, and it has always posed itself as a major challenge to the radiologists and physicians. OBJECTIVE: This paper proposes a new algorithm which draws on discrete wavelet transform and adaptive K-means techniques to transmute the medical images implement the tumor estimation and detect breast cancer tumors in mammograms in early stages. It also allows the rapid processing of the input data. METHOD: In the first step, after designing a filter, the discrete wavelet transform is applied to the input images and the approximate coefficients of scaling components are constructed. Then, the different parts of image are classified in continuous spectrum. In the next step, by using adaptive K-means algorithm for initializing and smart choice of clusters' number, the appropriate threshold is selected. Finally, the suspicious cancerous mass is separated by implementing the image processing techniques. RESULTS: We Received 120 mammographic images in LJPEG format, which had been scanned in Gray-Scale with 50 microns size, 3% noise and 20% INU from clinical data taken from two medical databases (mini-MIAS and DDSM). The proposed algorithm detected tumors at an acceptable level with an average accuracy of 92.32% and sensitivity of 90.24%. Also, the Kappa coefficient was approximately 0.85, which proved the suitable reliability of the system performance. CONCLUSION: The exact positioning of the cancerous tumors allows the radiologist to determine the stage of disease progression and suggest an appropriate treatment in accordance with the tumor growth. The low PPV and high NPV of the system is a warranty of the system and both clinical specialists and patients can trust its output.

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