Delayed neuropsychiatric syndrome of acute carbon monoxide poisoning from oak burning gas cured by therapy combined with transplantation of human umbilical cord blood stem cell, injection of nicholine, and intranasal inhalation of insulin.

A 55-year-old woman was admitted for the delayed neuropsychiatric syndrome of carbon monoxide (CO) poisoning (NSCs) from oak burning. Brain MRI showed diffuse high-intensity lesions on T2-weighted images of the left frontal and the occipital lobe. Treatment: The patient received transplantation of umbilical cord blood (UCB) stem cells, combined with injection of nicholine, intranasal inhalation of insulin.Outcomes: On the 24th day of hospitalization, the patient's orientation was improved. The brain MRI on the 75th day showed greatly decreased lesions. On the 86th day, all symptoms were disappeared. Conclusion: This new therapy is promising for the treatment of delayed NSCs.