RESUMEN
Nerve conduction was studied in various sensory and motor leg nerves in diabetics. Distal nerves were more affected than proximal ones. There was a poor correlation between neurographic results and the severity of clinical symptoms. No relationship was found between the degree of alteration of the individual neurographic parameter and the duration of diabetes and the fasting blood glucose level.
Asunto(s)
Neuropatías Diabéticas/fisiopatología , Pierna/inervación , Neuronas Motoras/fisiología , Conducción Nerviosa , Neuronas Aferentes/fisiología , Potenciales de Acción , Adolescente , Adulto , Niño , Preescolar , Femenino , Humanos , Masculino , Nervio Ciático/fisiopatologíaRESUMEN
Thirty patients with diabetes mellitus were investigated. Twenty-seven had clinical signs of a symmetrical sensory or sensorimotor polyneuropathy. Features of autonomic dysfunction were found in 17 patients. Nerve conduction was studied in the femoral, deep peroneal, saphenous, sural and sensory and motor fibres of the posterior tibial nerves. The postural heart rate response was tested in all of the 30 patients. There was only a weak correlation between autonomic disturbances and sensorimotor polyneuropathy, based either on clinical or on electrophysiological results. Thus a multifactorial causation is suspected.