RESUMEN
BACKGROUND: This study investigates the conservative management of radiation-induced early nasal adhesion after radiotherapy for nasopharyngeal carcinoma (NPC). METHODS: From June 2008 to June 2010, patients with bilateral or unilateral early nasal adhesion after radiotherapy for NPC were selected. All patients received endoscopic management and then nasal irrigation daily and nasal steroids spray for at least 3 months. All of the clinical data and follow-up endoscopy were analyzed. RESULTS: There were 40 patients enrolled. The mean follow-up period was 19.6 months (range, 12-24 months) after procedure. Thirty-eight patients (95%) had patent nasal cavity during follow-up. Two patients (5%) had not received endoscopy regularly and developed severe fibrosis. For the whole group, nasal obstruction, rhinorrhea, hyposmia, and xerostomia all were improved from before management according to visual analog score (p < 0.05). CONCLUSION: Therapeutic endoscopy in combination with nasal steroid sprays and nasal irrigation provides a convenient, simple, effective, and minimally invasive therapy to treat early radiation-induced nasal adhesion patients.
Asunto(s)
Glucocorticoides/administración & dosificación , Lavado Nasal (Proceso) , Neoplasias Nasofaríngeas/complicaciones , Enfermedades Nasales/diagnóstico , Enfermedades Nasales/terapia , Radioterapia Adyuvante/efectos adversos , Adulto , Anciano , Carcinoma , Diagnóstico Precoz , Femenino , Estudios de Seguimiento , Humanos , Masculino , Persona de Mediana Edad , Lavado Nasal (Proceso)/métodos , Rociadores Nasales , Carcinoma Nasofaríngeo , Neoplasias Nasofaríngeas/radioterapia , Enfermedades Nasales/etiología , Adherencias Tisulares/diagnóstico , Adherencias Tisulares/terapia , Resultado del TratamientoRESUMEN
<p><b>OBJECTIVE</b>To investigate the feasibility of the endoscope-assisted styloidectomy.</p><p><b>METHODS</b>Sixty patients with Eagle's syndrome undergoing the endoscope-assisted styloidectomy via postauricular incision, including 7 unilateral and 53 bilateral, between June 2010 and March 2013 were reviewed.</p><p><b>RESULTS</b>The styloid processes in all patients were resected successfully via this approach, with the incision length range of 2.0 to 2.5 cm. The mean operative time was (21.3 ± 4.8) min(X(-) ± s), for unilateral surgery and (48.5 ± 11.4) min for bilateral surgery. Fifty-four patients symptom showed complete remission of symptom, 3 cases with decrease in symptom and other 3 cases with no significant relief of symptom after surgery. None case recurred for follow-up of 3 to 70 months. There were 3 sides with ear numbness after surgery for 3 months, and one case had transient facial paralysis and recovered after 3 months.</p><p><b>CONCLUSIONS</b>The endoscope-assisted styloidectomy via postauricular incision is effective and feasible.</p>