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Genetika ; 37(8): 1125-37, 2001 Aug.
Artículo en Ruso | MEDLINE | ID: mdl-11642114

RESUMEN

The study continues the series of works on the Russian gene pool. Gene geographic analysis of four serum gene markers best studied in the Russian population (HP, GC, PI, and TF) has been performed. Gene-geographic electronic maps have been constructed for 14 alleles of these loci and their correlations with geographic latitude and longitude. For all maps, statistical characteristics are presented, including the variation range and mean gene frequencies, partial and multiple correlations with latitude and longitude, and parameters of heterozygosity and interpopulation diversity. The maps of five alleles (HP*1, GC*2, GC*1S, PI*M2, and TF*C2) are shown and analyzed in detail. The genetic relief and structural elements of the maps are compared with the ecumenical trends, main variation patterns of these genes in northern Eurasia, and genetic characteristics of the indigenous populations of the Urals and Europe.


Asunto(s)
Proteínas Portadoras/genética , Pool de Genes , Marcadores Genéticos , Haptoglobinas/genética , Transferrina/genética , alfa 1-Antitripsina/genética , Geografía , Humanos , Federación de Rusia , Vitamina D/metabolismo
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