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1.
IEEE Trans Nucl Sci ; 61(3): 1174-1181, 2014 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-25484379

RESUMEN

Waveform sampling is an appealing technique for instruments requiring precision time and pulse-height measurements. Sampling each PMT waveform at oscilloscope-like rates of several gigasamples per second enables one to process PMT signals digitally, which in turn makes it straightforward to optimize timing resolution and amplitude (energy and position) resolution in response to calibration effects, pile-up effects, and other systematic sources of waveform variation. We describe a system design and preliminary implementation that neatly maps waveform-sampling technology onto the LaPET prototype whole-body time-of-flight PET scanner that serves as the platform for testing this new technology.

8.
EMBO J ; 8(6): 1785-92, 1989 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-2504586

RESUMEN

Induction of c-fos transcription by serum growth factors requires a 20 bp DNA sequence termed the serum response element (SRE). The SRE is a binding site for a nuclear protein, serum response factor (SRF). There is as yet no direct evidence that links SRF activity to SRE function. We show here that cells contain a second specific SRE-binding protein. It is distinguished from SRF by its size, chromatographic properties, binding specificity and contacts with nucleotides in the SRE. The presence in cells of two distinct proteins that can bind independently to the SRE suggests that the multiple functions of the SRE may be mediated by distinct proteins.


Asunto(s)
Fosfoproteínas/metabolismo , Proteínas Proto-Oncogénicas/metabolismo , Animales , Secuencia de Bases , Sitios de Unión , Sondas de ADN , Proteínas de Unión al ADN/metabolismo , Humanos , Ratones , Fosforilación , Proteínas Proto-Oncogénicas/genética , Proteínas Proto-Oncogénicas c-fos , Transcripción Genética
10.
Oral Surg Oral Med Oral Pathol ; 61(6): 537-41, 1986 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-3459980

RESUMEN

A survey was done of 116 graduate training programs in oral and maxillofacial surgery to determine (1) the percentage of patients screened for orthognathic surgery who had symptoms of temporomandibular pain and dysfunction preoperatively and (2) how many who were asymptomatic preoperatively developed temporomandibular symptoms postoperatively. Of the fifty-one programs that responded, most reported that fewer than 20% of the patients were symptomatic before surgery and that few patients had symptoms postoperatively. The implications of these findings are discussed.


Asunto(s)
Maloclusión/complicaciones , Trastornos de la Articulación Temporomandibular/epidemiología , Humanos , Maloclusión/fisiopatología , Maloclusión/cirugía , Maloclusión/terapia , Ortodoncia Correctiva , Complicaciones Posoperatorias , Cirugía Bucal/educación , Trastornos de la Articulación Temporomandibular/etiología , Trastornos de la Articulación Temporomandibular/fisiopatología , Trastornos de la Articulación Temporomandibular/cirugía , Estados Unidos
13.
Lancet ; 2(8253): 994, 1981 Oct 31.
Artículo en Inglés | MEDLINE | ID: mdl-6117766
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