Primary cutaneous immunocytoma: report of an unusual case with secondary spreading to the gastrointestinal tract.

Cutaneous immunocytoma are low-grade B-cell lymphomas, which affect the skin either primarily or secondarily. Primary cutaneous immunocytomas usually present with one or a small number of lesions, mainly in the extremities. They generally remain confined to the skin. Histologically, there are polymorphous infiltrates of cells, in which the presence of monoclonal plasma cells is characteristic. We describe a case of cutaneous immunocytoma with secondary spread to the gastrointestinal tract.

Autoimmune cytopenias in pernicious anemia: a report of four cases and review of the literature.

Pernicious anemia appears to be autoimmune in origin and is associated with immune disorders of several organ systems. We report 4 patients with pernicious anemia and immune cytopenias, an association that may sometimes pose diagnostic problems unless specifically considered. Pernicious anemia coexisted with or was closely followed by idiopathic thrombocytopenic purpura in 3 patients and by autoimmune hemolytic anemia in a 4th patient. In addition to cobalamin therapy, all patients required corticosteroids (2 also received danazol), while 1 also required splenectomy. All 4 patients were women. The 3 patients with idiopathic thrombocytopenic purpura were also blood group O and were iron-deficient. Autoimmune cytopenias may occur in patients with treated or untreated pernicious anemia and require specific therapy.