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1.
Indian J Otolaryngol Head Neck Surg ; 65(Suppl 2): 220-5, 2013 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-24427650

RESUMEN

ENT surgeons are familiar with anatomy as well as physiology to improve the form and function of the nose. Conventional septoplasty is done to improve the function of the nose. The nasal septum contributes to the shape of the nose in many ways like it's height, length and position in the midline. And if septoplasty is extended to vary its' dimensions it can grossly contribute to the improvement of the shape of the nose and would truly be called septo-rhinoplasty. This fact that septal surgery alone can improve the shape of the nose shall encourage young ENT surgeons to practice these techniques and offer the resulting cosmetic advantages to their patients.

2.
Int J Clin Pharmacol Res ; 24(2-3): 79-94, 2004.
Artículo en Inglés | MEDLINE | ID: mdl-15689054

RESUMEN

Allergic rhinitis is the most frequently occurring immunological disorder. It affects men, women and children and represents significant cost in terms of suffering and loss of productivity. Allergy is termed as an excessive reaction to an environmental allergen. Pollen, mold, dust, mite and animal allergens that contact the nasal or eye lining cause sneezing, nasal congestion and itchy, watery, swollen, red eyes. Although a broad spectrum of therapeutic options is available, the treatment of allergic rhinitis appears to be far from satisfactory. A novel polyherbal formulation (PF; Aller-7/NR-A2) comprising seven medicinal herbal extracts was assessed in a multicenter clinical trial involving 545 patients (321 males and 224 females) aged 18-59 years for 12 weeks to evaluate its clinical efficacy in patients suffering from allergic rhinitis. A total of 171 patients participated in double-blind, randomized, placebo-controlled studies in three centers, while 374 patients were included in the open-label studies in 11 centers. The three major symptoms (sneezing, rhinorrhea and nasal congestion) of allergic rhinitis were significantly reduced. Significant improvement was also observed in absolute eosinophil count, mucociliary clearance time, peak expiratory flow rate and peak nasal flow rate. No serious adverse events that warranted cessation of treatment were observed. Minor adverse effects were noted in both the treatment and placebo groups. Thus, this study demonstrates that Aller-7/NR-A2 is well tolerated and efficacious in patients with allergic rhinitis.


Asunto(s)
Fitoterapia , Extractos Vegetales/uso terapéutico , Plantas Medicinales/química , Rinitis Alérgica Estacional/tratamiento farmacológico , Adulto , Enfermedad Crónica , Método Doble Ciego , Combinación de Medicamentos , Eosinófilos/citología , Eosinófilos/efectos de los fármacos , Femenino , Medicina de Hierbas , Humanos , Inmunoglobulina E/sangre , Inmunoglobulina E/efectos de los fármacos , Masculino , Depuración Mucociliar/efectos de los fármacos , Depuración Mucociliar/fisiología , Pruebas de Provocación Nasal/métodos , Pacientes Desistentes del Tratamiento/estadística & datos numéricos , Ápice del Flujo Espiratorio/efectos de los fármacos , Ápice del Flujo Espiratorio/fisiología , Extractos Vegetales/efectos adversos , Extractos Vegetales/química , Rinitis Alérgica Estacional/diagnóstico , Rinitis Alérgica Estacional/fisiopatología , Pruebas Cutáneas/métodos , Resultado del Tratamiento
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