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1.
Gan To Kagaku Ryoho ; 46(5): 945-947, 2019 May.
Artículo en Japonés | MEDLINE | ID: mdl-31189822

RESUMEN

The patient was a 65-year-old man. His complaints included bloody stools and pain on urination. A detailed examination suggested vesical wall invasion, leading to a diagnosis of rectosigmoid cancer(cT4b, N+, M0). For R0 surgery, total cystectomy was considered necessary. To maintain vesical function, tumor-reducing chemotherapy was selected. After colostomy for the sigmoid colon, 4 courses of mFOLFOX6 plus bevacizumab therapy were administered. There was a marked reduction in the tumor size; therefore, 3 courses of mFOLFOX6 plus panitumumab therapy were administered as preoperative chemotherapy before resection. Partial response(PR)was achieved, and there was no urinary bladder infiltration. Therefore, surgery was performed. There was no tumor invasion to any other organ. High anterior rectal resection was performed. The pathological diagnosis also confirmed the efficacy of chemotherapy. We report about a patient in whom extended surgery could be avoided by administering chemotherapy for advanced rectosigmoid cancer with urinary bladder invasion.


Asunto(s)
Terapia Neoadyuvante , Neoplasias del Recto , Neoplasias del Colon Sigmoide/terapia , Anciano , Protocolos de Quimioterapia Combinada Antineoplásica , Fluorouracilo , Humanos , Leucovorina , Masculino , Invasividad Neoplásica , Compuestos Organoplatinos , Neoplasias del Recto/terapia , Vejiga Urinaria
2.
Gan To Kagaku Ryoho ; 45(1): 160-162, 2018 Jan.
Artículo en Japonés | MEDLINE | ID: mdl-29362341

RESUMEN

Laparoscopic stoma creation enables good visualization of viscera within the abdominal cavity to ensure adequate mobilization of the large intestine. Laparoscopic stoma creation/construction was indicated and performed at our hospital in 7 patients who were diagnosed with unresectable colorectal cancer between July 2015 and May 2017. Duringthe ileostomy procedure, we made a skin incision at the stoma site and performed a single-incision(3-port)laparoscopic surgery. For the colostomy procedure, we made a small incision at the umbilicus and mobilized the large intestine with laparoscopic dissection of any interveningadhesions. Operation time ranged between 34 and 127 minutes, and the volume of intraoperative blood loss was low in all cases. There were no fatal complications related to the operation. Laparoscopic stoma creation can be performed safely and may be useful for staging of malignant colorectal tumors and reducing the risk of complications.


Asunto(s)
Neoplasias Colorrectales/cirugía , Laparoscopía , Adulto , Anciano , Anciano de 80 o más Años , Colostomía/métodos , Femenino , Humanos , Laparoscopía/métodos , Masculino , Persona de Mediana Edad
3.
Gan To Kagaku Ryoho ; 42(12): 2297-9, 2015 Nov.
Artículo en Japonés | MEDLINE | ID: mdl-26805343

RESUMEN

An 87-year-old man visited our hospital with a chief complaint of melena. Invagination caused by rectal cancer or sigmoid colon cancer was suspected as a result of physical and radiological examinations. Since there were no subjective symptoms, laparoscopic surgery was planned electively. As an operative finding, a tumor was found in the rectosigmoid colon and caused invagination. The invagination was released during an operation, and high anterior resection with D3 dissection was performed laparoscopically. The operation time was 108 minutes and the amount of blood loss was 22 mL. Although anastomotic leakage occurred as a postoperative complication, recovery was achieved conservatively by percutaneous drainage. In many cases, invagination of adults is caused by a solid tumor such as bowel carcinoma, which commonly occurs at the cecum or sigmoid colon. Although invagination of the rectosigmoid colon fixed to the retroperitoneum is relatively rare, the fragility of the supporting tissues in the pelvis accompanied by aging is considered to be a cause. In cases of a large tumor occupying the lumen of the intestine, appropriate preoperative diagnosis is needed and the method of operation should be chosen carefully.


Asunto(s)
Adenocarcinoma/cirugía , Intususcepción/cirugía , Neoplasias del Colon Sigmoide/patología , Adenocarcinoma/complicaciones , Anciano de 80 o más Años , Anastomosis Quirúrgica , Humanos , Intususcepción/etiología , Laparoscopía , Masculino , Estadificación de Neoplasias , Neoplasias del Colon Sigmoide/complicaciones , Neoplasias del Colon Sigmoide/cirugía
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