Asunto(s)
Enfermedades Hematológicas/cirugía , Esplenectomía , Adolescente , Adulto , Anemia Hemolítica/cirugía , Niño , Preescolar , Procedimientos Quirúrgicos Electivos , Femenino , Estudios de Seguimiento , Humanos , Masculino , Púrpura Trombocitopénica Idiopática/cirugía , Estudios Retrospectivos , Esferocitosis Hereditaria/cirugía , Resultado del Tratamiento , Talasemia beta/cirugíaAsunto(s)
Albendazol/uso terapéutico , Antihelmínticos/uso terapéutico , Equinococosis Pulmonar/tratamiento farmacológico , Equinococosis Pulmonar/cirugía , Adolescente , Niño , Preescolar , Terapia Combinada , Equinococosis Pulmonar/diagnóstico por imagen , Femenino , Estudios de Seguimiento , Humanos , Masculino , Complicaciones Posoperatorias , Radiografía , Resultado del Tratamiento , TurquíaRESUMEN
A 2-year-old boy with hemimegalencephaly and Hirschsprung's disease is reported. The unique association of these two entities is considered to be the presence of a common insult or insults that affect the innervation of the bowel and the formation of the cerebral cortex. Short-segment subtype of Hirschsprung's disease may suggest that this effect occurred between the eighth and twelfth weeks of gestation. Although there is a well-known coexistence of Hirschsprung's disease with the malformations that share a common neurocristopathic origin (abnormalities of neural crest cell growth, migration, or differentiation), a few extremely rare cases, as in this case, might reflect the coexistence of Hirschsprung's disease with a cerebral malformation (i.e., hemimegalencephaly) that is a nonneurocristopathic entity by itself.