RESUMEN
The main results of thirty-year period of repeated screening programs and observational studies in contaminated and non-contaminated regions of Belarus are analyzed. The possible reasons of discrepant and contradictory data about the consequences of Chernobyl catastrophe delivered by different study groups during early period after the accident are discussed. High incidence of thyroid nodular disease and cancer in children and adolescence after the catastrophe are described. The research shows high effectiveness of screening in early diagnosis thyroid disorders and radiation-induced thyroid cancer in different regions of Belarus and in various time points.
Asunto(s)
Accidente Nuclear de Chernóbil , Detección Precoz del Cáncer/estadística & datos numéricos , Rayos gamma/efectos adversos , Neoplasias Inducidas por Radiación/epidemiología , Neoplasias de la Tiroides/epidemiología , Nódulo Tiroideo/epidemiología , Adolescente , Niño , Monitoreo del Ambiente , Femenino , Humanos , Incidencia , Masculino , Neoplasias Inducidas por Radiación/diagnóstico , Neoplasias Inducidas por Radiación/patología , Dosis de Radiación , República de Belarús/epidemiología , Neoplasias de la Tiroides/diagnóstico , Neoplasias de la Tiroides/patología , Nódulo Tiroideo/diagnóstico , Nódulo Tiroideo/patología , UcraniaRESUMEN
Recently, radiofrequency ablation has been increasingly used for the treatment of thyroid nodules. The widespread introduction of this method, however, hampered by the lack of data on efficacy and safety of different devices that are currently on the market, the selection of the optimal mode of procedure also remains to be elucidated. Experimental data obtained during the application of the original patented device is presented. The results make it possible to move from ex vivo experiments to clinical practice.
Asunto(s)
Adenoma/cirugía , Ablación por Radiofrecuencia/métodos , Cáncer Papilar Tiroideo/cirugía , Neoplasias de la Tiroides/cirugía , Nódulo Tiroideo/cirugía , Adenoma/patología , Diseño de Equipo , Histocitoquímica , Humanos , Microtomía , Ablación por Radiofrecuencia/instrumentación , Cáncer Papilar Tiroideo/patología , Glándula Tiroides/patología , Glándula Tiroides/efectos de la radiación , Glándula Tiroides/cirugía , Neoplasias de la Tiroides/patología , Nódulo Tiroideo/patologíaRESUMEN
In the last 60 years dramatically increased the content of nitrates in groundwater due to intensive use of nitrogen fertilizers in agriculture. Research in post-Chernobyl period has shown that a sharp increase in the incidence of thyroid cancer depends not only on the level of thyroid dose, but also on the level of nitrates in groundwater.
