[The use of antimicrobial preparations in preventing infectious wound complications after an operation on the kidney and upper urinary tract]. / Primenenie nekotorykh antimikrobnykh preparatov v profilaktike infektsionnykh ranevykh oslozhnenii posle operatsii na pochke i verkhnikh mochevykh putiakh.

Pre-, intra- and postoperative use of wide-spectrum antibiotics alone appeared insufficient to prevent postoperative infectious inflammation. Antiseptic chlorhexidine (0.02% solution) does not eradicate the infection focus either. Cleansing of the wound is effective provided antibacterial treatment of the operative wound is combined with intraoperative application of local long-acting antimicrobial plates gentacicol and solution of antiseptic sodium hypochlorite. The above approach results in a 3.5 times reduction in the number of infectious postoperative complications in patients operated on the kidney and upper urethra.

[Transcutaneous puncture drainage in suppurative destructive diseases of the perirenal cellular tissue]. / Chreskozhnoe punktsionnoe drenirovanie pri gnoino-destruktivnykh zabolevaniiakh okolopochechnoi kletchatki.

The authors introduce a new sparing therapy of pyodestructive lesions of the pararenal fat which comprises subcutaneous puncture drainage controlled by ultrasound with subsequent treatment of the purulent focus with a solution of a new antiseptic, sodium hypochlorite. The advantages of the above method over routine approaches include a 1.5-2-fold decrease in the treatment duration, minor traumatism, simplicity, effectiveness in severe conditions.

[Gentacycol--a delayed-action form of gentamicin in the treatment of suppurative infection]. / Gentatsikol--prolongirovannaia lekarstvennaia forma gentamitsina v lechenii gnoinoi inferktsii.

Efficacy of gentacycol was studied in the treatment of various purulent infections. It was used in therapy of hematogenic and traumatic osteomyelitis, wound infections, soft tissue abscesses, purulent diffuse peritonitis as a complication of comissural ileus or appendectomy, pyothorax, destructive pneumonia and mediastinitis. Gentacycol ++ was also used for the prophylaxis in cholecystectomy, herniotomy and other conditions. The favourable results were stated in 93 per cent of the cases.

[The prevention of infectious-inflammatory complications in operations on the kidney]. / Profilaktika infektsionnno-vospalitel'nykh oslozhnenii pri operatsiiakh na pochke.

The paper presented the experience in the prevention of infectious complications during the renal surgery developed both in the organ operated on (acute postsurgical pyelonephritis) and in the surgical wound later. The package of prophylactic measures was employed in 48 patients operated on for the diseases of kidneys and urinary tract (nephrolithiasis predominantly). It included aseptic, antiseptic techniques, antibacterial treatment and preventive treatment in the pre-, intra- and postoperative periods, as well as intraoperative irrigation of the wound with antiseptic solutions and postoperative local therapy. Antibacterial prophylaxis was started 3-5 days or at night before the indicated surgery. Antibiotics were administered only after a careful adjustment of the dosage. Their intravenous (mainly) injections were performed under the effect of preliminary anesthetics. Clinical materials for microbiological and pharmacokinetic monitoring were being taken during the operation. Sodium chloride solution was electrolyzed and the obtained sodium hypochloride was used for the sanation of pyogangrenous foci. Patients with pyodestructive renal lesions developed in the presence of active chronic or acute pyelonephritis and the drainage of the urinary tract underwent 5-7-day antibacterial therapy. The aforementioned preventive measures allowed the authors to gain a significant reduction in the incidence of postoperative pyelonephritis (from 94.2 to 31.2 per cent) and wound infection (from 19.2 to 8.3 per cent), as well as bacteremia (from 32.3 to 5.4). Postsurgical complications (acute pyelonephritis and wound infection), if appeared, ran a relatively favorable course and were cured 3-5 days later. Uroseptic conditions were not observed.