[New methodological approaches to the detection and quantitative registration of Salmonella in the study of water objects].

The paper gives data on the use of techniques to detect and register Salmonella in the water objects, by applying a new liquid nutrient medium. Experimental and field studies have shown its advantage over the accumulation media widely used in practical healthcare. It has been ascertained that the nutrient medium not only accumulates biomass, but also provides the restoration of the biological properties of uncultivated Salmonella species. The use of the nutrient medium at practical laboratories makes it possible to unify guidelines for the examination of water objects with varying degrees of biological pollution and to obtain the comparable results of analyses.

[Malaria in the Rostov Region: retrospective analysis of the malaria situation in 1952-2007].

In the Rostov Region, no cases of local malaria transmission have been notified since 1958, but cases of import malaria are recorded every year. The region is one of malaria-susceptible areas in the Russian Federation, which is characterized by intensive migration, the malariogenic potential sufficient for local transmission (malariogenic index 1.2), and the optimum conditions for resurgence of malaria when it is imported. The prevention of undesirable consequences of malaria importation requires the strict monitoring of feverish patients, cohorts of high-risk patients who go for trips to malaria-endemic countries.

[Crimean-Congo hemorrhagic fever in Rostov Province: the epidemiological characteristics of an outbreak]. / Krymskaia-Kongo gemorragicheskaia likhoradka v Rostovskoi oblasti: épidemiologicheskie osobennosti vspyshki.

The results of the epidemiological analysis of the outbreak of hemorrhagic fever which was caused by Crimean-Congo hemorrhagic fever virus and occurred during the period of July 3-19, 1999, in the Oblivskaya district of Rostov Province are presented. The specific epidemiological features of the outbreak have been determined. The possible versions of the appearance of the focus of infection and the role of Ixodes ticks in the circulation of the infective agent are discussed.

[Epidemiologic characterization of Brucellosis under modern conditions]. / Epidemiologicheskaia kharakteristika brutseleza v sovremennykh usloviiakh.

The spread of brucella infection under modern conditions of cattle breeding were studied with the foci in the Rostov region taken as an example. The main epidemiological features and tendencies of epidemiological importance were established. To find out specific antigen in different environmental objects, the approbation of the enzyme immunoassay test systems was carried out and the possibility of their use at the institutions of the State Sanitary and Epidemiological inspection was shown.

[The complex study of the epidemic situation and of the immunological structure of the population in brucellosis foci]. / Kompleksnoe izuchenie épidemicheskoi situatsii i immunologicheskoi struktury naseleniia v ochagakh brutselleza.

As the result of the complex clinico-laboratory examination of 265 cattle breeders working on 5 farms where cases of brucellosis among agricultural animals had been detected, 62 persons (21.8%) were found to have the positive reaction to brucellosis. A strikingly high proportion (38.3%) of infected persons was found among the workers of a cattle-feeding complex. Out of 62 persons with the positive reaction to brucellosis, 32 had different clinical manifestations of the disease. Treatment for all persons who needed it was organized, the rest were placed under dispensary observation. Regular complex clinico-laboratory examinations of cattle breeders to brucellosis were recommended.

[The clinico-epidemiological characteristics of the course of a mixed epidemic of influenza and respiratory syncytial infection in Novoshakhtinsk in the summer of 1986]. / Kliniko-épidemiologicheskie osobennosti techeniia smeshannoi épidemii grippa i respiratorno-sintsitial'noi infektsii v Novoshakhtinske letom l986 g.

In the summer of 1986 the epidemic, whose etiological agents were influenza viruses A (H1N1) and respiratory syncytial virus, was registered among the population of Novoshakhtinsk. In a number of mines 15.3-16.7% of the employees were affected. Influenza viruses A (H1N1) proved to be closely related in their antigenic and biological properties to viruses isolated in the USSR in March-June 1986, as well as to viruses A (H1N1), the etiological agents of the epidemic which developed in the USSR in October-December 1986.

[Characteristics of the clinical and immunologic safety of inactivated influenza vaccines in children undergoing multiple immunizations]. / Kharakteristika klinicheskoi i immunologicheskoi bezvrednosti grippoznykh inaktivirovannykh vaktsin dlia detei v usloviiakh mnogokratnoi immunizatsii.

In a strictly controlled epidemiological trial on 12,643 school children aged 11-14 years the reactogenic properties and safety of killed influenza chromatographic vaccine under the conditions of multiple immunization were studied. A single immunization dose of the vaccine (0.2 ml) contained the hemagglutinins of influenza viruses A/Philippines/82 (H3N3) and A/Kiev/59/79 (H1N1), 3.5 micrograms each. The preparation was introduced by means of a jet injector. The vaccine was shown to be clinically and immunologically safe under the conditions of the regular multiple immunization of children over the period of 4 years.

[Approaches to determining the extent of tetanus immunity using an immunoenzyme method]. / Podkhody k opredeleniiu napriazhennosti immuniteta k stolbniaku s pomoshch'iu immunofermentnogo metoda.

The immunological survey of 3435 cattle-breeders of the Rostov region was carried out with the use of the enzyme immunoassay (EIA). The survey made it possible not only to establish the intensity of collective anti-tetanus immunity, but also to evaluate the quality of immunization. Among subjects with the known history of immunization the protective antitoxic titer was detected in 96.8 +/- 1.2% of cases and among subjects whose immunization history was unknown, in 75.3 +/- 0.8% of cases.