Feline eosinophilic keratoconjunctivitis: nonsteroidal vs corticosteroid topical treatment

Background: Feline eosinophilic keratoconjunctivitis is a proliferative eye lesion of chronic aspect with usually unilateralpresentation that may initiate as a superficial vascularization that evolves to a proliferative, granular, irregular lesion ofwhitish-pink aspect. With its association with an immune-mediated response, nonsteroidal anti-inflammatories do notappear to be efficient, although few studies describe its use. This case report describes a case of a feline eosinophilic keratoconjunctivitis with its clinical evolution since the use of nonsteroidal topical anti-inflammatory drug in an undiagnosedpatient and the transition to a topical corticosteroid and cure after 14 days since diagnosis.Case: An 8-year-old female cat was attended at the Veterinary Hospital of the Dom Bosco Catholic University (UCDB),with main complaint being an eye injury with at least 36 days of evolution and unresponsive to treatment (topical tobramycin 0.3% every 12 h / ketorolac trometamol 0.5%/ every 12 h and ophthalmic lubricant/every 4 h). Since the patienthad free access to the street, the owners suspected of trauma-induced lesion. At physical examination, it was observed aproliferative lesion at the peri-limbal superotemporal quadrant of the right cornea with approximately 0.4 cm diameter,with color varying of pale to pink, with irregular surface and low vascularity, the adjacent conjunctiva was also affectedwith similar multiple nodular lesions (0.1 cm). Fluorescein test was negative as well as FIV/FeLV immunochromatographytesting. Feline herpesvirus investigation was not possible. The patient was anesthetized and a lesion specimen was acquiredwith a cotton swab scraping and a fine needle aspiration. Cytology showed predominance of eosinophils and mast cells,with rare corneal epithelial cells, with smear background containing mast cell...(AU)

Feline eosinophilic keratoconjunctivitis: nonsteroidal vs corticosteroid topical treatment

Background: Feline eosinophilic keratoconjunctivitis is a proliferative eye lesion of chronic aspect with usually unilateralpresentation that may initiate as a superficial vascularization that evolves to a proliferative, granular, irregular lesion ofwhitish-pink aspect. With its association with an immune-mediated response, nonsteroidal anti-inflammatories do notappear to be efficient, although few studies describe its use. This case report describes a case of a feline eosinophilic keratoconjunctivitis with its clinical evolution since the use of nonsteroidal topical anti-inflammatory drug in an undiagnosedpatient and the transition to a topical corticosteroid and cure after 14 days since diagnosis.Case: An 8-year-old female cat was attended at the Veterinary Hospital of the Dom Bosco Catholic University (UCDB),with main complaint being an eye injury with at least 36 days of evolution and unresponsive to treatment (topical tobramycin 0.3% every 12 h / ketorolac trometamol 0.5%/ every 12 h and ophthalmic lubricant/every 4 h). Since the patienthad free access to the street, the owners suspected of trauma-induced lesion. At physical examination, it was observed aproliferative lesion at the peri-limbal superotemporal quadrant of the right cornea with approximately 0.4 cm diameter,with color varying of pale to pink, with irregular surface and low vascularity, the adjacent conjunctiva was also affectedwith similar multiple nodular lesions (0.1 cm). Fluorescein test was negative as well as FIV/FeLV immunochromatographytesting. Feline herpesvirus investigation was not possible. The patient was anesthetized and a lesion specimen was acquiredwith a cotton swab scraping and a fine needle aspiration. Cytology showed predominance of eosinophils and mast cells,with rare corneal epithelial cells, with smear background containing mast cell...

Clinical and radiographic aspects of metacarpal remodeling secondary to a rubber band (latex) compression in a dog

Background: Musculoskeletal disorders are a common complaint in veterinary small animal casuistic. Along with fractures, degenerative and of carcinogenic etiology are the most frequent and radiographic lesion pattern at these diseases isrelative well defined. However, traumatic lesions, considering its innumerous possibilities, may cause unusual clinical andradiographic signs which will delay diagnosis and consequently, adequate treatment. A case of bone osteolysis caused bya compressive trauma by a rubber band is described with its clinical, laboratorial and radiographic aspects.Case: A 2-year-old female dog was attended at the Veterinary Hospital of the Dom Bosco Catholic University (UCDB),with main complaint being an unresponsive to treatment lesion at the left thoracic limb. At physical examination it wasobserved lameness of the left thoracic limb with an ulcerative lesion at the palmar surface. At the center of the ulcer a 0.3cm line shaped yellow object was identified, similar to a rubber band. Traction was made and the object distended 5 cmwithout breaking nor leaving the injury. Showing signs of discomfort, the patient was then sedated for further manipulation. A blood sample for complete blood count and serum biochemistry was collected and radiographic image of the leftcarpometacarpal-phalangeal region was acquired. Blood analysis revealed moderate thrombocytopenia with an unremarkable serum biochemistry profile (alanine aminotransferase, alkaline phosphatase, creatinine and urea). It was observedmetacarpals with increased radiopacity in bone tissue in the mid-diaphysis topography of the II, III, IV and V metacarpalbones, presence of bone remodeling with radiolucent area and slight bone loss (osteolysis) in the mid-diaphysis associatedwith discrete sclerosis of the medullary cavity of the II, III and V metacarpals. The patient was submitted to surgery and a3 cm incision was made following the way...(AU)

Clinical, laboratorial and image aspects of a perforated pyloric ulcer secondary to nonsteroidal anti-inflammatory use in a cat

Background: Inappropriate use of drugs for veterinary patients represents a common problem at clinical practice. Nonsteroidal anti-inflammatories are one of these misused drugs and may lead to clinical status of challenging diagnosis. Adverseeffects for patients submitted to its incorrect use may include simple cases such as pharmacological gastroenteritis to severeacute renal failure or perforated gastroenteric ulcers with no pathognomonic clinical signs. The objective of this reportwas to describe a case of a perforated pyloric ulcer secondary to prolonged use of meloxicam in a cat with its clinical,laboratorial and image aspects from the moment of suspicion until the diagnosis.Case: An 8-year-old female feline was attended at the Veterinary Hospital of the Dom Bosco Catholic University, withmain complaint being a mammary nodule with recent ulceration. Tumor staging and pre-surgical blood analysis wereperformed previous to total unilateral mastectomy. Eleven days post-surgery the patient was brought for suture removal,but it was observed stupor, moderate dehydration (estimated 10%), 36.7ºC rectal temperature, heart rate at 100 beats/min,respiratory rate at 60 breaths/min, 40 mg/dL blood glucose, icterus and abdominal distension with tympany at percussion(fluid wave test was negative). Anamnesis revealed the possible use of meloxicam for 10 days. The first suspicion wassepsis, with enteric gas secondary to infection. Due to no classical signs of peritoneum effusion and possible severe entericdistension, abdominocentesis was not immediate performed. Complete blood count and serum biochemistry revealed amarked band leukocytosis associated with renal injury, supporting the first sepsis suspicion. Abdominal radiography revealedradiodensity of diffuse aspect at ventral topography but no evidence of marked...(AU)

Clinical, laboratorial and image aspects of a perforated pyloric ulcer secondary to nonsteroidal anti-inflammatory use in a cat

Background: Inappropriate use of drugs for veterinary patients represents a common problem at clinical practice. Nonsteroidal anti-inflammatories are one of these misused drugs and may lead to clinical status of challenging diagnosis. Adverseeffects for patients submitted to its incorrect use may include simple cases such as pharmacological gastroenteritis to severeacute renal failure or perforated gastroenteric ulcers with no pathognomonic clinical signs. The objective of this reportwas to describe a case of a perforated pyloric ulcer secondary to prolonged use of meloxicam in a cat with its clinical,laboratorial and image aspects from the moment of suspicion until the diagnosis.Case: An 8-year-old female feline was attended at the Veterinary Hospital of the Dom Bosco Catholic University, withmain complaint being a mammary nodule with recent ulceration. Tumor staging and pre-surgical blood analysis wereperformed previous to total unilateral mastectomy. Eleven days post-surgery the patient was brought for suture removal,but it was observed stupor, moderate dehydration (estimated 10%), 36.7ºC rectal temperature, heart rate at 100 beats/min,respiratory rate at 60 breaths/min, 40 mg/dL blood glucose, icterus and abdominal distension with tympany at percussion(fluid wave test was negative). Anamnesis revealed the possible use of meloxicam for 10 days. The first suspicion wassepsis, with enteric gas secondary to infection. Due to no classical signs of peritoneum effusion and possible severe entericdistension, abdominocentesis was not immediate performed. Complete blood count and serum biochemistry revealed amarked band leukocytosis associated with renal injury, supporting the first sepsis suspicion. Abdominal radiography revealedradiodensity of diffuse aspect at ventral topography but no evidence of marked...

Clinical and radiographic aspects of metacarpal remodeling secondary to a rubber band (latex) compression in a dog

Background: Musculoskeletal disorders are a common complaint in veterinary small animal casuistic. Along with fractures, degenerative and of carcinogenic etiology are the most frequent and radiographic lesion pattern at these diseases isrelative well defined. However, traumatic lesions, considering its innumerous possibilities, may cause unusual clinical andradiographic signs which will delay diagnosis and consequently, adequate treatment. A case of bone osteolysis caused bya compressive trauma by a rubber band is described with its clinical, laboratorial and radiographic aspects.Case: A 2-year-old female dog was attended at the Veterinary Hospital of the Dom Bosco Catholic University (UCDB),with main complaint being an unresponsive to treatment lesion at the left thoracic limb. At physical examination it wasobserved lameness of the left thoracic limb with an ulcerative lesion at the palmar surface. At the center of the ulcer a 0.3cm line shaped yellow object was identified, similar to a rubber band. Traction was made and the object distended 5 cmwithout breaking nor leaving the injury. Showing signs of discomfort, the patient was then sedated for further manipulation. A blood sample for complete blood count and serum biochemistry was collected and radiographic image of the leftcarpometacarpal-phalangeal region was acquired. Blood analysis revealed moderate thrombocytopenia with an unremarkable serum biochemistry profile (alanine aminotransferase, alkaline phosphatase, creatinine and urea). It was observedmetacarpals with increased radiopacity in bone tissue in the mid-diaphysis topography of the II, III, IV and V metacarpalbones, presence of bone remodeling with radiolucent area and slight bone loss (osteolysis) in the mid-diaphysis associatedwith discrete sclerosis of the medullary cavity of the II, III and V metacarpals. The patient was submitted to surgery and a3 cm incision was made following the way...