Comportamento da membrana biossintética de celulose como implante peritendíneo em potros / Behavior of cellulose biosynthetic membrane as a peritendinous implant in foals

Background: Tendon injuries are common in horses and are commonly associated with lameness and athletic career disruption.Adhesions formed between the tendons and the surrounding tissues compromise the sliding and movement of the structures,compromising their functionality. Therefore, the control of adhesion formation is critical to restore the structural integrity of thetendon, as well as its biomechanical function. The aim of this study was to evaluate the behavior of the biosynthetic cellulosemembrane implanted in foals with surgically induced tendinitis of the superficial digital flexor.Materials, Methods & Results: Six healthy foals were used, which underwent tendinitis induction in the superficial digital flexorof the right and left forelimbs. The lesions was induced by local ischemia by crushing the tendon with hemostatic forceps. Thebiosynthetic cellulose membrane was implanted only in the right forelimb, involving the superficial digital flexor tendon in theregion of the ischemia and the left forelimb was used as control. After surgery, both forelimb were immobilized with syntheticplaster cast for 15 days. Ultrasonography was performed in six foals immediately before (M0), at 15° (M1) at and 30° (M2) day,and three were evaluate at 45° (M3) and 60° (M4) day after surgery. Incisional biopsies were performed in three animals on the30° day and in three animals on the 60° day after surgery. Histopathological examination involved the analysis of tissue disorganization, presence and type of inflammatory infiltrate and neovascularization, according to the score of 0 to 3. Ultrasonographyallowed visualization of the membrane, which was characterized as a continuous hyperechoic line at the edges of the tendon at15 days (M1). In addition, at 30 and 45 days after surgery, interruption of the hyperechoic line and reduction of echogenicitywere observed, and no echogenic lines were observed at 60 days after surgery...

Comportamento da membrana biossintética de celulose como implante peritendíneo em potros / Behavior of cellulose biosynthetic membrane as a peritendinous implant in foals

Background: Tendon injuries are common in horses and are commonly associated with lameness and athletic career disruption.Adhesions formed between the tendons and the surrounding tissues compromise the sliding and movement of the structures,compromising their functionality. Therefore, the control of adhesion formation is critical to restore the structural integrity of thetendon, as well as its biomechanical function. The aim of this study was to evaluate the behavior of the biosynthetic cellulosemembrane implanted in foals with surgically induced tendinitis of the superficial digital flexor.Materials, Methods & Results: Six healthy foals were used, which underwent tendinitis induction in the superficial digital flexorof the right and left forelimbs. The lesions was induced by local ischemia by crushing the tendon with hemostatic forceps. Thebiosynthetic cellulose membrane was implanted only in the right forelimb, involving the superficial digital flexor tendon in theregion of the ischemia and the left forelimb was used as control. After surgery, both forelimb were immobilized with syntheticplaster cast for 15 days. Ultrasonography was performed in six foals immediately before (M0), at 15° (M1) at and 30° (M2) day,and three were evaluate at 45° (M3) and 60° (M4) day after surgery. Incisional biopsies were performed in three animals on the30° day and in three animals on the 60° day after surgery. Histopathological examination involved the analysis of tissue disorganization, presence and type of inflammatory infiltrate and neovascularization, according to the score of 0 to 3. Ultrasonographyallowed visualization of the membrane, which was characterized as a continuous hyperechoic line at the edges of the tendon at15 days (M1). In addition, at 30 and 45 days after surgery, interruption of the hyperechoic line and reduction of echogenicitywere observed, and no echogenic lines were observed at 60 days after surgery...(AU)

Trans-endoscopic ventriculocordectomy in horses using monopolar electrocautery / Ventriculocordectomia trans-endoscópica em equinos, com uso de eletrocautério monopolar

Laryngeal hemiplegia is one of the most common upper airway affections in horses. Laringoplasty is indicated in high-performance animals, and when the only complaint is noisy breathing, ventriculectomy and cordectomy can be performed. This study aimed to establish a minimally invasive surgical approach to ventriculocordectomy in horses, through a videoendoscopic procedure. The technique was developed in two stages, the first one was a cadaveric study and the second one was in vivo, both using two flexible endoscopes. A bilateral ventriculocordectomy was performed in two cadavers, totaling the removal of four vocal cords. In the second stage, a left unilateral ventriculocordectomy was performed in three animals with laryngeal hemiplegia. The vocal cords were pulled by one of the endoscopes with 3.2mm grasping forceps, while the second equipment was used for the resection of vocal cords with a flexible electrode adapted for monopolar electrosurgery (electrocautery). The average time for removal of the vocal cords was 23±5 minutes. In the postoperative care, moderate inflammation around the surgical wound was observed, with complete healing in 21 days in one horse and 28 days in the other two. One animal presented exuberant granulation tissue on the surgical site. Other complications due to the tested technique were not noticed; therefore, it could be a less invasive option for ventriculocordectomy in horses. The developed technique proved to be effective for ventriculocordectomy execution in horses. The main advantages of this approach were reduced surgical time, shorter healing average time, no need for daily dressings and return to normal activities in a shorter period when compared to other surgical approaches. The limitation of the technique consists of the need for two endoscopes for its accomplishment. Further studies, with more animals, are needed to improve the technique.(AU)

Hemiplegia de laringe representa uma das afecções mais frequentes em vias aéreas anteriores de cavalos. Em animais de alto desempenho esportivo a laringoplastia é indicada, e nos casos em que a única queixa é o ruído respiratório recomenda-se realizar a ventriculectomia e a cordectomia. O presente trabalho teve como objetivo estabelecer uma abordagem cirúrgica minimamente invasiva, através de videocirurgia, para realização da ventriculocordectomia em cavalos. A técnica cirúrgica foi desenvolvida em duas etapas, sendo a primeira cadavérica e a segunda in vivo, ambas utilizando videoendoscópios flexíveis. A primeira consistiu na realização de ventriculocordectomia bilateral em dois cadáveres, para padronização da técnica, totalizando quatro cordas vocais removidas. Na segunda, procedeu-se a ventriculocordectomia unilateral esquerda em três animais naturalmente afetados pela hemiplegia de laringe. As cordas vocais foram tracionadas utilizando uma pinça de preensão de 3,2mm, através do canal de trabalho de endoscópio flexível, e com o segundo equipamento similar, realizou-se a ressecção da corda vocal com eletrodo flexível monopolar adaptado para eletrocirurgia (eletrocautério), também através do canal de trabalho. O tempo médio dos procedimentos foi de 23±5 minutos. No período pós-operatório observou-se moderada inflamação ao redor da incisão, sendo o tempo de cicatrização total de 21 dias em um cavalo e 28 dias nos outros dois. Um dos animais apresentou tecido de granulaçãoexuberante no local de excisão da corda vocal, que foi tratado com infiltração de corticosteróide. Nãoforam observadas outras intercorrências inerentes à técnica proposta, sendo esta uma opção poucoinvasiva, que dispensa a realização da laringotomia. A técnica desenvolvida no presente trabalhomostrou-se promissora para realização da ventriculocordectomia em cavalos. As principais vantagensdesta abordagem foram: tempo trans cirúrgico reduzido, tempo médio de cicatrização menor...(AU)

Trans-endoscopic ventriculocordectomy in horses using monopolar electrocautery / Ventriculocordectomia trans-endoscópica em equinos, com uso de eletrocautério monopolar

Laryngeal hemiplegia is one of the most common upper airway affections in horses. Laringoplasty is indicated in high-performance animals, and when the only complaint is noisy breathing, ventriculectomy and cordectomy can be performed. This study aimed to establish a minimally invasive surgical approach to ventriculocordectomy in horses, through a videoendoscopic procedure. The technique was developed in two stages, the first one was a cadaveric study and the second one was in vivo, both using two flexible endoscopes. A bilateral ventriculocordectomy was performed in two cadavers, totaling the removal of four vocal cords. In the second stage, a left unilateral ventriculocordectomy was performed in three animals with laryngeal hemiplegia. The vocal cords were pulled by one of the endoscopes with 3.2mm grasping forceps, while the second equipment was used for the resection of vocal cords with a flexible electrode adapted for monopolar electrosurgery (electrocautery). The average time for removal of the vocal cords was 23±5 minutes. In the postoperative care, moderate inflammation around the surgical wound was observed, with complete healing in 21 days in one horse and 28 days in the other two. One animal presented exuberant granulation tissue on the surgical site. Other complications due to the tested technique were not noticed; therefore, it could be a less invasive option for ventriculocordectomy in horses. The developed technique proved to be effective for ventriculocordectomy execution in horses. The main advantages of this approach were reduced surgical time, shorter healing average time, no need for daily dressings and return to normal activities in a shorter period when compared to other surgical approaches. The limitation of the technique consists of the need for two endoscopes for its accomplishment. Further studies, with more animals, are needed to improve the technique.

Hemiplegia de laringe representa uma das afecções mais frequentes em vias aéreas anteriores de cavalos. Em animais de alto desempenho esportivo a laringoplastia é indicada, e nos casos em que a única queixa é o ruído respiratório recomenda-se realizar a ventriculectomia e a cordectomia. O presente trabalho teve como objetivo estabelecer uma abordagem cirúrgica minimamente invasiva, através de videocirurgia, para realização da ventriculocordectomia em cavalos. A técnica cirúrgica foi desenvolvida em duas etapas, sendo a primeira cadavérica e a segunda in vivo, ambas utilizando videoendoscópios flexíveis. A primeira consistiu na realização de ventriculocordectomia bilateral em dois cadáveres, para padronização da técnica, totalizando quatro cordas vocais removidas. Na segunda, procedeu-se a ventriculocordectomia unilateral esquerda em três animais naturalmente afetados pela hemiplegia de laringe. As cordas vocais foram tracionadas utilizando uma pinça de preensão de 3,2mm, através do canal de trabalho de endoscópio flexível, e com o segundo equipamento similar, realizou-se a ressecção da corda vocal com eletrodo flexível monopolar adaptado para eletrocirurgia (eletrocautério), também através do canal de trabalho. O tempo médio dos procedimentos foi de 23±5 minutos. No período pós-operatório observou-se moderada inflamação ao redor da incisão, sendo o tempo de cicatrização total de 21 dias em um cavalo e 28 dias nos outros dois. Um dos animais apresentou tecido de granulaçãoexuberante no local de excisão da corda vocal, que foi tratado com infiltração de corticosteróide. Nãoforam observadas outras intercorrências inerentes à técnica proposta, sendo esta uma opção poucoinvasiva, que dispensa a realização da laringotomia. A técnica desenvolvida no presente trabalhomostrou-se promissora para realização da ventriculocordectomia em cavalos. As principais vantagensdesta abordagem foram: tempo trans cirúrgico reduzido, tempo médio de cicatrização menor...