Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 1 de 1
Filtrar
Más filtros










Base de datos
Intervalo de año de publicación
1.
Curr Biol ; 32(8): 1703-1714.e3, 2022 04 25.
Artículo en Inglés | MEDLINE | ID: mdl-35245457

RESUMEN

Sexually dimorphic courtship behaviors in Drosophila melanogaster develop from the activity of the sexual differentiation genes, doublesex (dsx) and fruitless (fru), functioning with other regulatory factors that have received little attention. The dissatisfaction (dsf) gene encodes an orphan nuclear receptor homologous to vertebrate Tlx and Drosophila tailless that is critical for the development of several aspects of female- and male-specific sexual behaviors. Here, we report the pattern of dsf expression in the central nervous system and show that the activity of sexually dimorphic abdominal interneurons that co-express dsf and dsx is necessary and sufficient for vaginal plate opening in virgin females, ovipositor extrusion in mated females, and abdominal curling in males during courtship. We find that dsf activity results in different neuroanatomical outcomes in females and males, promoting and suppressing, respectively, female development and function of these neurons depending upon the sexual state of dsx expression. We posit that dsf and dsx interact to specify sex differences in the neural circuitry for dimorphic abdominal behaviors.


Asunto(s)
Proteínas de Drosophila , Drosophila , Animales , Cortejo , Proteínas de Unión al ADN/metabolismo , Drosophila/fisiología , Proteínas de Drosophila/metabolismo , Drosophila melanogaster/fisiología , Femenino , Masculino , Proteínas del Tejido Nervioso/metabolismo , Receptores Citoplasmáticos y Nucleares , Caracteres Sexuales , Conducta Sexual Animal/fisiología , Factores de Transcripción/genética , Factores de Transcripción/metabolismo
SELECCIÓN DE REFERENCIAS
DETALLE DE LA BÚSQUEDA
...