RESUMEN
T1 G3 bladder carcinoma are classified as superficial tumours and treatment results are included in low stage tumour groups. A review of survival rates shows that there is a high risk of progression about 50-70%. The grade is by now considered the most significant prognostic factor and many other prognostic biological tests have been suggested. We treated 41 cases of T1G3 bladder tumours with a first therapeutic TUR and second staging TUR two months later. Subsequently a group of 15 has had "wait" and see" endoscopic follow-up with bad results, a group of 7 underwent "early cystectomy", a group of 12 has been treated with adjuvant cytotoxic chemotherapy with poor results on recurrence and good results on progression percentages, a group of 6 radiotherapy with poor results. We got confirmation of high risk of progression, 4 cases with high stage from beginning, 3 with precocious metastatic disease. Apart the cases with precocious metastases, the best survival rates are achieved with early cystectomy.
Asunto(s)
Carcinoma de Células Transicionales/terapia , Neoplasias de la Vejiga Urinaria/terapia , Carcinoma de Células Transicionales/mortalidad , Carcinoma de Células Transicionales/patología , Quimioterapia Adyuvante , Terapia Combinada , Cistectomía , Estudios de Seguimiento , Humanos , Metástasis de la Neoplasia , Recurrencia Local de Neoplasia , Tasa de Supervivencia , Factores de Tiempo , Vejiga Urinaria/patología , Neoplasias de la Vejiga Urinaria/mortalidad , Neoplasias de la Vejiga Urinaria/patologíaRESUMEN
The improvement of the endoscopic strumentation and technique has permitted a large diffusion of the transurethral resection of the vesical (TURV) for malignant neoplasms. We report the complications of this method described in literature and a review of the cases observed at the Urological Division of Niguarda Hospital in Milan from January 1985 to December 1989 has presented. The adequate treatment of the complications permits to minimize the damage for the patient.