RESUMEN
DNA of H-1, H-5, H-10, H-17, and H-22 phages were studied, their nucleotide composition, their buoyant densities in cesium chloride and cesium sulphate, curves of melting and spectra of circular dichroism were determined 5-oxymethylcytosine in the composition of H-I and H-22 phage DNA was shown immunologically to be glucozylated.
Asunto(s)
Bacteriófagos/análisis , ADN Viral , 5-Metilcitosina/análogos & derivados , Centrifugación por Gradiente de Densidad , Fenómenos Químicos , Química Física , Dicroismo Circular , Citosina/análogos & derivados , Citosina/análisis , Calor , Nucleótidos/análisis , Shigella , Especificidad de la EspecieRESUMEN
Physico-chemical properties of dysentery therapeutic-prophylactic Newcastle phages H-I, H-5, H-10, H-22 were studied. The morphology of the phage particles is described; their molecular weight and buoyant density in CsCl were determined by ultracentrifugation. The type of nucleic acids (DNA) was determined. By all the above characteristics and their chemical composition, bacteriophages of the Newcastle group approach T-even phages.