Estimate of lysine nutritional requirements for Japanese quail breeders.

Background: Japanese quail breeders are the basis for genetic improvement and multiplication for commercial layers, however, there have been no known studies on the optimal lysine level for these birds. Thus, study the egg output response to the lysine (Lys) supply using different e-functions and evaluate the that best fit, have allowed the partition the lysine requirements for maintenance, both weight and egg output maximum. Methods: The objectives of this study were to identify the responses to various Lys levels, identify the functions related to these responses and determine the ideal Lys intake amount for Japanese quail breeders. A completely randomized design of seven treatments with seven replicated was used. Treatments consisted of diet supplementation by Lys in concentrations of 16.8, 11.8, 8.4, 6.7, 5.0, 3.4, and 1.7 g/kg. Six exponential models were adjusted. Results: The level of Lys was found to affect bird responses (P < 0.001). The birds responded to the levels provided, allowing for the creation of a lysine response curve. A monomolecular function with four parameters was balanced against the statistics of adjustment and selection of models. It was possible to estimate the level of lysine required for maintenance as 133 ± 2 mg/kg BW0.67, and based an average of 41% efficiency, 22 mg Lys produced 1 g of egg output (EO). The daily intake calculated by the monomolecular factorial model was 284 mg Lys for a bird with 0.170 kg body weight and production of 10 g EO/day. The four-parameter monomolecular function proposed in this study is adequate for interpreting the animal response and calculating lysine intake for breeders.

Modeling the response of Japanese quail to arginine intake.

Background: Understanding how Japanese quails respond to arginine intake has been an objective that previous studies have not fulfilled. The main responses to be quantified include the arginine requirement for maintenance (mg/kg0.67) and egg mass production (mg/g). Quantifying maintenance and production relationships are essential steps for predicting animal response. The current study aimed to describe how quails respond to arginine intake and determine arginine requirements for maintenance and egg production in Japanese quails. Methods: The experiment was carried out in a completely randomized design, with seven treatments and seven replicates with individual birds as experimental units. The arginine levels were: 2.43, 3.64, 4.85, 6.07, 9.07, 12.13, and 14.56 g/kg. The experiment lasted for eight weeks. The variables analyzed were daily arginine intake, daily arginine deposition in eggs, and body weight. The data were analyzed using a mixed model, with the experimental unit being the random effect and the experimental levels of arginine as a fixed effect. When the effect of arginine levels was detected (P ≤ 0.05), saturation kinetics and an exponential model with four parameters (monomolecular) were adopted. ANOVA results indicated that dietary arginine levels significantly affected (P < 0.01) the analyzed variables. The formulation strategy of the experimental diets allowed amplitude in the dietary arginine levels, and according to bird responses, arginine was the limiting nutrient. Results: The arginine requirement for body weight maintenance (BW0.67) was estimated to be 90 mg/kg BW0.67 by the monomolecular function. The requirement for egg mass (EM) production was estimated to be 25 mg/g per egg. A factorial model was parameterized as follows: daily arginine intake mg/bird = 90 × BW0.67 + 25 × EM ± 12 mg. The model was applied to data obtained from literature, and the resultant error was within the expected limit of 12 mg. The recommended daily arginine intake for the daily production of 11 g of egg and 180 g of BW was determined to be 304 mg/bird. The current study provides procedures that researchers can easily adopt.

Arginine requirement for egg production in Japanese quail.

The objective of this study was to determine the ideal arginine intake for egg production in Japanese quail using the dilution technique. A completely random design was used, with 8 treatments (seven concentrations of arginine plus a control diet) and ten replicates, totaling 80 Japanese quails. The digestible arginine levels included in the study were 0.361%, 0.603%, 0.843%, 1.084%, 1.204%, 1.311%, and 1.460%. The variables analyzed were feed intake, egg production (EP), egg weight, egg output (EO), feed conversion ratio, and body weight were performed using a mixed model. When the effect of arginine levels (P ≤ 0.05) was detected, the model's broken line linear-plateau (BL), quadratic-plateau (BLq), and the first intercept of the BLq in the plateau of BL were adjusted to determine the ideal arginine intake. It observed that the arginine levels modified the quail responses (P < 0.001). Egg production was 10% with the 0.361% arginine in diet and recovered (97%) with the 1.311% arginine diet. The BL and BLq models estimated 232 mg/quail per day and 351 mg/quail per day for EO, respectively. The first intercept obtained was 290 mg/quail per day or 1,411%, which was considered the optimum level arginine intake for EO in Japanese quail.

Lifestyle of public transport bus drivers and fare collectors / Estilo de vida de motoristas e cobradores do transporte coletivo / Estilo de vida de condutores y cobradores de transporte colectivo

Objective: Analyze and compare the lifestyle of public transport drivers and fare collectors. Methods: Descriptive, quantitative and cross-sectional study with 88 bus drivers and 75 fare collectors from Florianópolis, Santa Catarina, Brazil. To determine the domain scores (nutrition, physical activity, preventive behavior, social relationship and stress control), the Individual Lifestyle Profile questionnaire and anamnesis were applied. Data collection took place from September to October 2016. The maximum significance level assumed was 5% (p≤0.05). Chi-square test was used to assess the association between responses and job function, and T-test for independent samples was used to compare variables between groups. Results: There was a statistical difference (p>0.001) between bus drivers and fare collectors for age (40,36±8,55; 31,30 ± 8,68 years), time in function (11,47±8,53; 6,14±5,46 years) and time in the transport company (12,8±6,64; 6,35±5,56 years) and there was no association between the answers of the questions and the function performed (p>0.05). Considering the five domains, the workers showed negative behavior for nutrition (p=0.68) and physical activity (p=0.50), and regular behavior for preventive behavior (p=0.09), social relationships (p=0.45) and stress control (p=0.98), without significant differences between groups. Conclusion: Comparing bus drivers and fare collectors, it is noteworthy that there are differences in age, time in function and time in the company, but not in lifestyle and the public transport workers have a negative lifestyle profile in nutrition and physical activity.

Objetivo: Analisar e comparar o estilo de vida dos motoristas e cobradores de tarifa do transporte público. Métodos: Estudo descritivo, quantitativo e transversal, com 88 motoristas de ônibus e 75 cobradores de tarifa de Florianópolis, Santa Catarina, Brasil. Para determinar os escores dos domínios (nutrição, atividade física, comportamento preventivo, relacionamento social e controle do estresse) aplicou-se o questionário Perfil Individual do Estilo de Vida e anamnese. A coleta de dados decorreu entre setembro e outubro de 2016. Considerou-se o nível de significância máximo assumido 5% (p≤0,05) e usou-se o teste qui-quadrado para avaliar a associação entre as respostas e a função do trabalho, e teste T para amostras independentes para comparar as variáveis entre os grupos. Resultados: Houve diferença estatística (p>0,001) entre motoristas de ônibus e cobradores de tarifa para: idade (40,36±8,55; 31,30±8,68 anos), tempo na função (11,47±8,53; 6,14±5,46 anos) e tempo na empresa (12,8±6,64; 6,35±5,56 anos), e não houve associação das respostas das perguntas com a função desempenhada (p>0,05). Considerando os cinco domínios, os trabalhadores apresentaram comportamento negativo para nutrição (p=0,68) e atividade física (p=0,50), e comportamento regular para comportamento preventivo (p=0,09), relações sociais (p=0,45) e controle de estresse (p=0,98), sem diferenças significativas entre grupos. Conclusão: Comparando-se os motoristas de ônibus e os cobradores de tarifa investigados, destaca-se que há diferenças na idade, no tempo na função e no tempo na empresa, mas não no estilo de vida, e que trabalhadores do transporte público possuem um perfil de estilo de vida negativo nos domínios de nutrição e atividade física.

Objetivo: Analizar y comparar el estilo de vida de los conductores y cobradores de tasas del transporte público. Métodos: Estudio descriptivo, cuantitativo y transversal con 88 conductores de autobuses y 75 cobradores de tarifa de Florianópolis, Santa Catarina, Brasil. Se aplicó el cuestionario Perfil Individual del Estilo de Vida y anamnesis para determinar las puntuaciones de los dominios (nutrición, actividad física, conducta de prevención, relacionamiento social y el control del estrés). La recogida de datos se dio entre septiembre y octubre de 2016. Se ha considerado el nivel de significancia máximo del 5% (p≤0,05) y se ha utilizado la prueba de chi-cuadrado para evaluar la asociación entre las respuestas y la función del trabajo, la prueba T para muestras independientes para comparar las variables entre los grupos. Resultados: Hubo diferencia estadística (p>0,001) entre los conductores de autobús y los cobradores de tarifa para: edad (40,36±8,55; 31,30±8,68 años), tiempo de función (11,47±8,53; 6,14±5,46 años) y tempo en la empresa (12,8±6,64; 6,35±5,56 años) y no hubo asociación entre las respuestas de las preguntas y la función realizada (p>0,05). Considerándose los cinco dominios, los trabajadores presentaron conducta negativa para nutrición (p=0,68) y actividad física (p=0,50), y conducta regular para la conducta de prevención (p=0,09), las relaciones sociales (p=0,45) y el control del estrés (p=0,98), sin diferencias significativas entre los grupos. Conclusión: Comparándose los conductores de autobús y los cobradores de tarifa investigados, destacase que hay diferencias en la edad, en el tempo de función y en el tiempo de empresa pero no en el estilo de vida, y que los trabajadores del transporte público tiene un perfil de estilo de vida negativo para los dominios nutrición y actividad física.

Early and late results of topical diltiazem and bethanechol for chronic anal fissure: a comparative study.

BACKGROUND/AIMS: Late efficacy of medical treatment of chronic anal fissure remains controversial due to high recurrence. This study aimed at analyzing safety and efficacy of topical diltiazem and bethanechol regarding healing and symptoms relief, safety, recurrence, and need for surgery. METHODOLOGY: This was a single-center nonrandomized trial. Outcomes of 30 patients with chronic anal fissure treated with 2% diltiazem were compared to 30 patients treated with 0.1% bethanechol, both for eight weeks. Patients were assessed after seven days and eight weeks. RESULTS: In diltiazem group, after seven days, 31% were symptomatic; after bethanechol, 71% (p = 0.06). After seven days, fissure healing occurred in 19% after diltiazem and in 11% after bethanechol. After eight weeks, in both groups, 64% were asymptomatic; after diltiazem, 53% healed; after bethanechol, 50% (p = 0.80). Success was the same for both groups: 63.3%. Groups were similar regarding complications. After diltiazem, 9 (30%) patients were operated on; and 11 (36.7%) after bethanechol (p = 0.60). Recurrence occurred in 4 (13.3%) patients in both groups. Median time to recurrence after diltiazem was 15 (10-24) months and 7.5 (2-15) after bethanechol - p = 0.15. CONCLUSIONS: Both treatments are safe and effective. Diltiazem may be associated to earlier relief and more sustained response.

Stapled hemorrhoidectomy vs closed diathermy-excision hemorrhoidectomy without suture-ligation: a case-controlled trial.

BACKGROUND/AIMS: We compared stapled hemorrhoidectomy to closed diathermy-excision hemorrhoidectomy without suture-ligation regarding postoperative pain, complications and long-term efficacy. METHODOLOGY: A series of 108 patients had indication for stapled hemorrhoidectomy. Patients who underwent stapled hemorrhoidectomy (76) were compared to patients submitted to closed diathermy-excision hemorrhoidectomy (32) due to non-insurance cover. Primary endpoints were postoperative pain, complications, and clinical results after one year. Patients completed a 10-cm visual analog pain scale postoperatively and fulfilled a questionnaire before and 12 months after surgery. RESULTS: After seven days, median and maximum daily pain scores were lower in the stapled group (P < 0.001). Resumption of activities occurred after 9 days (mean; range 2 to 17 days) after stapling and 14 days (7 to 24) after diathermy surgery - P < 0.001. There was no difference regarding complications during the follow-up. After one year, 45 (80.4%) patients in the stapled group and 18 (78.3%) in the diathermy group were asymptomatic (P = 1.000). After one year, none of the patients needed a second operation and there was no fecal incontinence. CONCLUSIONS: Stapled hemorrhoidectomy selectively indicated is less painful, not associated to greater morbidity and has the same long-term efficacy when compared to closed diathermy excision without suture-ligation.

Impacto da vídeocirurgia na prevenção de aderências / Impact of the video-surgery in the prevention of the adhesions

Uma das vantagens aventadas da vídeo-cirurgia é a possibilidade de formar menos aderências pós-operatórias. As evidências deste efeito resultam de trabalhos clínicos e experimentais, mas o real impacto desta via de acesso neste sentido ainda não foi comprovado. O objetivo da presente revisão foi avaliar as evidências científicas disponíveis sobre o assunto. MATERIAL E MÉTODOS: revisão da literatura pertinente. RESULTADOS: as aderências pós-operatórias foram analisadas no sítio da operação e nas incisões praticadas, porém existem poucas informações sobre aderências em locais não operados. Aderências pós-operatórias são menos freqüentes ou intensas quando se considera a via de acesso por vídeo. A despeito deste dado experimental, os desfechos clínicos de menor dor pélvica, menor número de admissões ou reoperações por obstrução intestinal e menor ocorrência de infertilidade ainda não podem ser claramente atribuídos a esta via de acesso, especialmente quando se consideram as cirurgias laparoscópicas avançadas, uma vez que nesta situação existe equivalência de área cruenta nas duas vias de acesso, à exceção da área associada às incisões. CONCLUSÕES: a via de acesso por vídeo está associada a menor formação de aderências, mas não protege de complicações relacionadas à sua ocorrência. Técnica operatória adequada e o uso de barreiras provavelmente estão mais fortemente associadas à menor formação de aderências do que a via de acesso aberta empregada para a realização das operações abdominais e pélvicas.