Asunto(s)
Diabetes Mellitus Tipo 2/dietoterapia , Dieta para Diabéticos/tendencias , Diabetes Mellitus/dietoterapia , Dieta Reductora , Carbohidratos de la Dieta/administración & dosificación , Grasas de la Dieta/administración & dosificación , Proteínas en la Dieta/administración & dosificación , Ingestión de Energía , Humanos , ObesidadRESUMEN
The authors carried out studies on 28 women with the syndrome of Stein-Leventhal with obesity. It was established that patients with hypothalamic genuine obesity of III degree predominated. The number of patients with liver steatosis was the largest among accompanying metabolic disturbances, followed by those with arterial hypertension and asymptomatic hyperuricemia. Menarche occurred on time, but it was succeeded by various menstrual disturbances. There was increased level of testosterone in sera of 12 out of 20 examined women patients, of LH-in 17, of 17-ketosteroids-in 8, of estrogens-in 6, of prolactin-in 8 patients. These data in parallelism between menstrual disturbances and hirsutism were interpreted by the authors as an expression of primary disturbances in hypothalamic-hypophysial-gonadal interrelationships with secondary changes in the ovaries. The role of fatty tissue in the metabolism of steroid hormones is discussed as well as the possibility for participation of genetic factors in the development of the syndrome of Stein-Leventhal and obesity.
Asunto(s)
Obesidad/diagnóstico , Síndrome del Ovario Poliquístico/diagnóstico , Femenino , Hirsutismo/sangre , Hirsutismo/diagnóstico , Hirsutismo/etiología , Hormonas/sangre , Humanos , Trastornos de la Menstruación/sangre , Trastornos de la Menstruación/diagnóstico , Trastornos de la Menstruación/etiología , Obesidad/sangre , Obesidad/etiología , Síndrome del Ovario Poliquístico/sangre , Síndrome del Ovario Poliquístico/etiología , RadioinmunoensayoRESUMEN
18 women suffering from nervous anorexia were studied. The onset of the disease was before the age of 25 years in all patients. The loss of body mass was between 25% and 40%, mean 32%. The onset of the disease was preceded by psychic trauma, negative attitude toward eating, in some cases there had been periods of bulimia, use of purgatives and diuretics. All patients had amenorrhea. In 44.44% of the patients hypercholesterolemia was found, in 72.80%-hypertriglyceridemia, in 54.54%--increased somatotropic hormone level, in 54.54%--increased ACTH level, in 72.80%, decrease of follicle-stimulating hormone level, in 81.80%--decrease of the luteinizing hormone, in 81.80%--decrease of triiodothyronine (T3), in 81.80%--decrease of estradiol and in 81.80%--increase of testosterone were found. The deviations found in the patients with nervous anorexia are considered as manifestations of chronic food deficiency and they disappear after regaining the normal body mass.
Asunto(s)
Anorexia Nerviosa/diagnóstico , Adolescente , Adulto , Anorexia Nerviosa/metabolismo , Anorexia Nerviosa/terapia , Enfermedad Crónica , Terapia Combinada , Femenino , Hormonas/análisis , Humanos , PronósticoRESUMEN
A case of a woman who complained of dryness of the mouth, eyes and lack of tears is presented. For the diagnosis traditional tests were used--Schirmer's test, gastric intubation, as well as modern immunologic methods--immunoglobulins of single-chain and natural anti-DNA antibodies, radioscintigraphy of the salivary glands. The positive Schirmer's test, the slow gastric secretion with normal secretion at the lower normal range, the positive natural and anti DNA antibodies with increased IgA, IgG, IgM, and the data of the radioscintigraphy of the salivary glands make an early diagnosis possible and facilitate a timely modern treatment.
Asunto(s)
Síndrome de Sjögren/patología , Quimioterapia Combinada , Femenino , Humanos , Persona de Mediana Edad , Síndrome de Sjögren/diagnóstico , Síndrome de Sjögren/tratamiento farmacológicoAsunto(s)
Neoplasias Cardíacas/complicaciones , Enfermedad de Hodgkin/complicaciones , Pericarditis/etiología , Adulto , Antineoplásicos/uso terapéutico , Femenino , Neoplasias Cardíacas/tratamiento farmacológico , Enfermedad de Hodgkin/tratamiento farmacológico , Humanos , Derrame Pericárdico/etiologíaAsunto(s)
Obesidad/metabolismo , Adenohipófisis/metabolismo , Prolactina/metabolismo , Adolescente , Adulto , Femenino , HumanosRESUMEN
The results from the carried out investigations on fertility indices of ejaculate are reported as well as on the spermatogenic activity test with radioactive phosphorus and on the determination of total gonadotropic excretion in urine of males with high degree of obesity. A statistically significant decrease of all investigated in dices of ejaculate and the test of spermatogenic activity was found. The decreased gonadotropic activity in over half of the patients investigated with obesity, as well as the manifestations of diencephalic alterations in them made the authors admit the secondary character of the gonad disorders.