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Rev Inst Med Trop Sao Paulo ; 36(2): 175-83, 1994.
Artículo en Portugués | MEDLINE | ID: mdl-7997796

RESUMEN

We report three cases of subcutaneous phaeohyphomycosis due to Exophiala jeanselmei (Langeron) McGinnis et Padhye 1977, in kidney transplant patients. Exophiala jeanselmei is a dematious fungus having also ability to rarely procedure eumycetoma (black grains). According to KWON-CHUNG & BENNETT (1992) such fungus is antigenically very heterogeneous, since so far three serotypes have been identified; each serotype including subgroups. Subcutaneous phaeohyphomycosis is becoming more and more frequent in kidney transplant patients submitted to an immunosuppressive treatment. As Exophiala jeanselmei has already been isolated from the environment it becomes difficult to explain the pathogenicity of these cases by a reactivation of quiescent processes. The authors suggest an occasional fungistatic action of cyclosporine A upon Exophiala jeanselmei.


Asunto(s)
Dermatomicosis/microbiología , Exophiala/aislamiento & purificación , Trasplante de Riñón/efectos adversos , Infecciones Oportunistas/microbiología , Adulto , Ciclosporina/uso terapéutico , Dermatomicosis/patología , Dermatomicosis/terapia , Exophiala/patogenicidad , Femenino , Humanos , Terapia de Inmunosupresión/efectos adversos , Masculino , Persona de Mediana Edad
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