RESUMEN
BACKGROUND: Development of neurological complications of varicella zoster virus reactivation is relatively uncommon, particularly in an immunocompetent child. CASE PRESENTATION: An 11-year-old Asian girl presented with headache and skin rash on her left chest. She was diagnosed with meningitis, and herpes zoster was confirmed by polymerase chain reaction using cerebrospinal fluid. Acyclovir was administered intravenously. Given the favorable evolution of the clinical course, she was discharged from the hospital on day 8 of her illness. She had no apparent sequelae or comorbidities at the time of the 6-week follow-up. CONCLUSIONS: Neurological complications such as meningitis due to varicella zoster virus reactivation are uncommon, especially in an immunocompetent child; no specific immune deficiency was identified in our patient. We conclude that, although rare, varicella zoster virus should be recognized as a potential cause of viral meningitis in immunocompetent children.
Asunto(s)
Aciclovir/administración & dosificación , Líquido Cefalorraquídeo/virología , Herpes Zóster , Herpesvirus Humano 3/aislamiento & purificación , Meningitis Viral , Administración Intravenosa , Antivirales , Niño , Exantema/diagnóstico , Exantema/etiología , Femenino , Cefalea/diagnóstico , Cefalea/etiología , Herpes Zóster/complicaciones , Herpes Zóster/diagnóstico , Herpes Zóster/tratamiento farmacológico , Herpes Zóster/fisiopatología , Humanos , Inmunocompetencia , Meningitis Viral/diagnóstico , Meningitis Viral/tratamiento farmacológico , Meningitis Viral/etiología , Meningitis Viral/fisiopatología , Resultado del TratamientoAsunto(s)
Proteínas Bacterianas/genética , Proteínas Bacterianas/aislamiento & purificación , Infección Hospitalaria/microbiología , Staphylococcus aureus Resistente a Meticilina/genética , Proteínas de Unión a las Penicilinas/genética , Proteínas de Unión a las Penicilinas/aislamiento & purificación , Staphylococcus aureus/genética , Antibacterianos/uso terapéutico , Proteínas Bacterianas/efectos de los fármacos , Infección Hospitalaria/tratamiento farmacológico , Brotes de Enfermedades , Hospitales Pediátricos , Humanos , Japón , Staphylococcus aureus Resistente a Meticilina/aislamiento & purificación , Proteínas de Unión a las Penicilinas/efectos de los fármacos , Penicilinas/uso terapéutico , Staphylococcus aureus/efectos de los fármacos , Staphylococcus aureus/aislamiento & purificaciónRESUMEN
In the spring of 2015, we experienced a cluster of 4 sporadic cases of yersiniosis in children in Nagano prefecture, a rural area of Japan. Two patients developed appendicitis-like episodes; one had acute gastroenteritis, and the other had bacteremia associated with liver abscess. The causative agent of these infections was Yersinia enterocolitica serogroup O:8. None of the patients had an underlying illness, and all have recovered completely. The patients were neither socially nor geographically related to each other. These 4 consecutive cases suggest that Y. enterocolitica O:8 has spread substantially in the middle part of Japan, and that this virulent strain might be more common than previously reported in our country.