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1.
Adv Exp Med Biol ; 1279: 53-59, 2020.
Artículo en Inglés | MEDLINE | ID: mdl-32350821

RESUMEN

Traumatic brain injury has ripple effect on the physical, cognitive, behavioral, and emotional domains of quality of life and portends a long-term neurological disability in survivors. In this study we evaluated the prognostic role of demographic and clinico-radiological variables on the hospitalization length and mortality in 71 of patients with frontal brain contusions. The receiver operating characteristic (ROC) plots were performed, with area under the curve (AUC) values, for graphical comparison of variables that would predict mortality and hospitalization length. We found that the best prognostics of mortality were the Glasgow Coma Scale score, the motor function score, and the Rotterdam CT score, with AUC values of 0.873, 0.836, and 0.711, respectively. Concerning the prediction of hospitalization length, the AUC showed inappreciable differences, with the highest values for the Glasgow Coma Scale score, Rotterdam CT score, and the serum cortisol level in a 0.550-0.600 range. Curve estimation, based on multivariate analysis, showed that the scores of motor function, Glasgow Coma Scale, and Rotterdam CT correlated best with the prediction of both mortality and hospitalization length, along with the upward dynamic changes of serum cortisol for the latter. We conclude that basically simple and non-invasive assessment in survivors of acute traumatic brain contusion is helpful in predicting mortality and the length of hospital stay, which would be of essential value in better allocation of healthcare resources for inpatient treatment and rehabilitation and for post-hospital patient's functioning.


Asunto(s)
Contusión Encefálica/diagnóstico , Contusión Encefálica/mortalidad , Lóbulo Frontal/patología , Tiempo de Internación/estadística & datos numéricos , Escala de Coma de Glasgow , Humanos , Pronóstico , Calidad de Vida , Resultado del Tratamiento
2.
F1000Res ; 6: 430, 2017.
Artículo en Inglés | MEDLINE | ID: mdl-28580129

RESUMEN

Orbital metastasis from lung cancer as an initial presenting symptom is a rare entity, which may paradoxically delay the diagnosis and initiation of correct management, due to the confusion of it being primary orbital pathology. Herein we report a case of a 58 year old woman, who presented with painful orbital swelling along with diminution in her vision. The patient was initially thought to have a primary eye lesion; however chest X-ray was suggestive of a lung mass, which was confirmed by chest computed topography followed by ultrasound guided fine needle aspiration cytology. The patient was then referred to a cancer centre for further management. This case report aims to increase the knowledge about this metastasis as a probable cause of orbital symptoms in certain subsets of patients, so that correct therapeutic decisions may be made in the future.

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