RESUMEN
BACKGROUND: The treatment of H. pylori-associated gastroduodenal disease is increasingly aimed at bacterial eradication which requires follow-up assessment of therapeutic effectiveness and re-infection. A simplified 37 kBq 14C-urea breath test for H. pylori infection has been developed. METHODS: The 37 kBq 14C-urea breath test was compared with biopsy urease (CLO) and histological analyses of gastric-biopsies obtained from 63 patients undergoing endoscopy. RESULTS: The 30-min breath test correlated closely with biopsy findings, had a sensitivity of 100%, a specificity of 95% and a positive predictive value of 92%. CONCLUSIONS: The simplified, low-dose, 14C-urea breath test is a convenient, low-cost, transportable means of facilitating the management of H. pylori-associated diseases.
Asunto(s)
Pruebas Respiratorias , Infecciones por Helicobacter/diagnóstico , Helicobacter pylori , Úlcera Péptica/microbiología , Estómago/patología , Urea , Biopsia , Radioisótopos de Carbono , Femenino , Gastroscopía , Humanos , Masculino , Persona de Mediana Edad , Úlcera Péptica/patología , Sensibilidad y EspecificidadRESUMEN
A patient with previously diagnosed Fabry's disease and a long history of post-prandial abdominal pain died following small bowel infarction. Post-mortem demonstrated Fabry's type deposits in the small vessels and nerves supplying the bowel but in addition, a localized atheromatous stenosis of the superior mesenteric artery. In retrospect, his terminal illness and possibly his chronic symptoms were related to the latter finding. Angioplasty to the superior mesenteric artery may have been of benefit. Mesenteric angiography should be considered in patients with chronic post-prandial pain because large vessel disease may coexist with other a priori pathologies and is imminently treatable.
Asunto(s)
Enfermedad de Fabry/complicaciones , Intestino Delgado/irrigación sanguínea , Isquemia/etiología , Arteriosclerosis/etiología , Arteriosclerosis/patología , Humanos , Infarto/etiología , Infarto/patología , Intestino Delgado/patología , Isquemia/patología , Masculino , Arteria Mesentérica Superior/patología , Oclusión Vascular Mesentérica/etiología , Oclusión Vascular Mesentérica/patología , Persona de Mediana EdadRESUMEN
This paper reviews the circumstances of 95 fatalities from electrical injuries. Eighty-nine were accidental, four were suicides and two occurred during autoerotic electrical stimulation. Forty-nine of the accidental fatalities occurred at work, Twenty-eight in the home and twelve in the course of outside recreational activities. In many accidents the circumstances were distressingly similar and included: (1) Contact with overhead distribution lines by a length of conductor such as a yacht mast or crane. (2) Faulty wiring or electrical repairs performed by unqualified people. (3) Badly deteriorated cords, plugs and occasionally appliances. (4) Failure to use isolating transformers when indicated. Deaths involving children are a particular cause of concern. Nine fatalites involved children under the age of five years who contacted inadequately protected wires.