[Polish multicenter study on diabetes type I incidence in he age group 0-14 between 1998 and 1999]. / Wieloosrodkowe badania nad zapadalnoscia na cukrzyce typu 1 w grupie wiekowej 0-14 lat w Polsce w latach 1998-1999.

The increase in diabetes type 1 incidence observed in various centers in Poland and the need for a centralized study covering large population have resulted in the construction of a standardized registry of type 1 diabetes in 1998 within the Polish Multicenter Study in Diabetes Epidemiology. The aim of the study was to present the incidence rates of type 1 diabetes in the age group 0-14 in 7 distinct regions of Poland (Krakow, Wroclaw, Warsaw, Bialystok, Poznan, Rzeszow and Olsztyn centers) with over 30% of the Polish population at risk in 1998 and 1999. The data for the standardized registry were obtained prospectively from paediatric hospital wards and diabetes outpatient units. The incidence rates calculated in 1998 showed the highest value of 14.6 and 14.5/100,000 for Olsztyn and Warsaw, and the lowest (8.4/100,000) for Poznan center. In 1999 the highest value of 14.7/100,000 was noted in Krakow and the lowest (9.3/100,000) in Poznan center. The differences in diabetes type 1 incidence rates between age groups 0-4, 5-9 and 10-14 were found to be significant (p < 0.0005) and were also significant when incidence rates were compared between males and females in these age groups in the whole study area in 1998-1999 (p = 0.002 and p = 0.015 respectively).

[Fluorophotometric study of juvenile insulin-dependent diabetic patients]. / Badania fluorofotometryczne u mlodziezy z cukrzyca insulinozalezna.

PURPOSE: The aim of this study is to find a correlation between fluorophotometric data, diabetes duration and patient's age. MATERIALS AND METHODS: A group of 19 patients (38 eyes) aged 11-23 years with juvenile-onset, insulin-dependent diabetes, treated for 2-17 years were examined using ocular fluorophotometry. Visual acuity, anterior segment and fundus as well as IOP, fluoroangiography and opacimetry were also examined. RESULTS: Anterior Chamber (AC) and Posterior Vitreous (PV) fluorescein concentration was higher in the group with mild background retinopathy (10 eyes) than in group with normal fundi (28 eyes). CONCLUSIONS: Diabetes duration over 15 years increases the risk of the development of diabetic retinopathy and increases fluorescein leakage through the blood-retinal barrier in juvenile insulin-dependent diabetes patients.