[Changes in the rosette-forming capacity of peripheral blood lymphocytes in patients with ischemic heart disease after administration of atherogenic lipoproteins]. / Izmenenie rozetkoobrazuiushchei sposobnosti limfotsitov perifericheskoi krovi bol'nykh ishemicheskoi bolezn'iu serdtsa pod deistviem lipoproteidov aterogennykh klassov.

Low-density lipoproteins, isolated from the serum of patients with hypercholesterolemia (dislipoproteinemia, type IIa), increased significantly the number of active and recovered rosette-forming cells (RFC) at incubation with lymphocytes of coronary patients. The use of lipoproteins, belonging to all atherogenic classes, did not essentially alter lymphocyte ability to form total E-RFC. Purified apolipoprotein B reduced lymphocyte capacity for active rosette formation.

[Isolation of split and whole-virion tick-borne encephalitis vaccines in an experiment and the characteristics of their immunogenic and antigenic properties]. / Poluchenie rasshcheplennoi i tsel'novirionnoi vaktsin kleshchevogo éntsefalita v éksperimente i kharakteristika ikh immunogennykh i antigennykh svoistv.

The split preparation, obtained by the treatment of purified and concentrated tick-borne encephalitis virus with 0.5% Tween-80 and ether and inactivated with formalin at a minimal concentration of 1:10,000, did not contain the active virus. After the removal of the detergent, the preparation retained its antigenic and immunogenic properties.

[Molecular biology characteristics of an attenuated mutant of the Eastern equine encephalomyelitis virus]. / Molekuliarno-biologicheskaia kharakteristika attenuirovannogo mutanta virusa vostochnogo éntsefalomielita loshadei.

The main molecular biology parameters of an attenuated mutant DMS-20/6 of eastern equine encephalomyelitis virus derived by treatment with dimethylsulphate of the wild type virus (strain No. 627) were determined. The sedimentation coefficient of sucrose density gradient purified and concentrated virus was 280 S, the buoyant density of virions in sucrose density gradient was 1.19 g/cm3. The DMS-20/6 virion had 3 proteins with molecular weights of 56, 50, and 34 kilodaltons, and the size of virions by negative staining was 58-77 nm.