RESUMEN
Clinical, histological and immunohystochemical studies of keratocystic tumors were performed showing differences in proliferative activity and MMP-9 expression scores in orthokeratinized and parakeratinised cysts. These histological features are associated with clinical course and may be used as markers for recurrence probability.
Asunto(s)
Enfermedades Mandibulares/metabolismo , Enfermedades Mandibulares/patología , Quistes Odontogénicos/metabolismo , Quistes Odontogénicos/patología , Adulto , Biomarcadores/metabolismo , Humanos , Antígeno Ki-67/metabolismo , Masculino , Enfermedades Mandibulares/cirugía , Metaloproteinasa 9 de la Matriz/metabolismo , Quistes Odontogénicos/cirugía , RecurrenciaRESUMEN
Clinical, histological and immunohystochemical studies of ameloblastomas were performed and tumor varieties according to proliferative activity and MMP-9 expression scores were identified. These histological features are associated with clinical course and may be used as markers for recurrence probability.
Asunto(s)
Ameloblastoma/diagnóstico , Neoplasias Maxilomandibulares/diagnóstico , Adolescente , Adulto , Anciano , Ameloblastoma/diagnóstico por imagen , Ameloblastoma/patología , Femenino , Humanos , Neoplasias Maxilomandibulares/diagnóstico por imagen , Neoplasias Maxilomandibulares/patología , Masculino , Metaloproteinasa 9 de la Matriz/análisis , Metaloproteinasa 9 de la Matriz/metabolismo , Persona de Mediana Edad , Radiografía , Adulto JovenRESUMEN
Ameloblastoma and ameloblastic fibroma are benign odontogenous tumors of the jaws with local destructive growth, prone to recurrence. They have various typical radiological and histological features. Surgical tactic generally includes partial resection of the affected jaw. Immunohistochemical study of the tumor tissues allows assessing the expression of tumor progression markers and forecasting tumor growth thus providing individual choice of surgical tactics. Our experience in treatment of ameloblastic tumors showed total biopsy with osseous surgical margins resection to be sufficient for normal bone structure remodeling in some patients.
