Percutaneous radiofrequency facet denervation in low-back and extremity pain.

The present series includes 47 patients (35 females 12 males) with an average observation time of 8 months after percutaneous lumbar facet denervation by radiofrequency electrocoagulation. All patients had static and kinetic lumbar pain; 90% of them had pain radiating into the legs. None had clinical or radiologic (radiculography and/or CT scan) evidence of a lumbar disc herniation, and all had exhausted conservative therapy. All but one had provocation of their habitual pain on arthrography of the relevant intervertebral lumbar joints and/or on intraoperative stimulation prior to electrocoagulation. 22/47 of the patients had no immediate or late beneficial effect of the electrocoagulation. Eight of the remaining 25 patients had satisfactory relief of pain at follow-up. The failures included all patients with previous multiple lumbar operations except for three.

Temporal lobe epilepsy. Follow-up investigation of 74 temporal lobe resected patients.

This survey covers 74 patients with temporal lobe epilepsy, resistant to medication, who underwent unilateral temporal lobectomy during the years 1960-1969 at Rigshospitalet, Copenhagen. Preoperatively all patients were socially incapacitated. In all patients a unilateral or predominantly unilateral temporal EEG focus was found. No tumour or gross vascular malformation had been recognized before or during operation. At follow-up 45 patients were free from seizures. A further 15 had obtained a reduction in their seizure frequencies by at least 75%, while the remaining 10 survivors, only obtained a slight improvement or remained unchanged. There were four deaths. The operation also favourably influenced the psychiatric status, which was found closely related to relief from seizures. Prognostically favourable factors were: i) preoperative presence of a single type of seizure, ii) duration of epilepsy of less than four years, iii) operation in or before early adulthood, iv) an anterior temporal or sphenoidal electrode focus, or both, on the EEG. The prognostically unfavourable factors regarding complete relief from seizures were: i) preoperative presence of grand mal, ii) age at onset of epilepsy or of the first grand mal seizure between 5 and 19 years of age, iii) preoperative duration of epilepsy of over ten years and of grand mal of over one year. Prognostically unfavourable factors regarding psychiatric normalization were: i) preoperative presence of psychosis, ii) ictal-affective attacks or automatisms of a complex nature, iii) impairment of intellectual functions. The eventual neuropathological conclusion was that the more specific and circumscribed the histological abnormality the better the final outcome. The social rehabilitation was found to be significantly improved by operation at an early age.

Stereotaxic amygdalotomy and basofrontal tractotomy in psychotics with aggressive behaviour.

Twelve patients with personality disorders or chronic schizophrenia in whom aggressive-destructive behaviour was a prominent feature were treated by bilateral stereotaxic electrocoagulation of the amygdala. In two of the patients a cingulectomy and in five of the patients a frontal lobotomy had been performed several years previously without effect. In 11 of the patients the amygdalotomy resulted in disappearance of, or marked reduction in, their aggressive episodes. In two patients with frequent self-mutilations and reactive psychotic episodes these symptoms disappeared after an additional basofrontal tractotomy by Knight's method.