[Splenic resection for the spleen cyst].

Tactics and results of surgical treatment of 5 patients for splenic cyst were analyzed. The original method of splenic cyst resection, using blood-preserving technologies (ultrasonic aspirator-destructor, the argon laser and hemostatics) was applied. The data obtained permit to consider the splenic resection performance an adequate procedure for the focal organ pathology treatment.

[Primary multiple malignant tumors of the stomach and colon]. / Pervichno-mnozhestvennye zlokachestvennye opukholi zheludka i tolstoi kishki.

Experience of diagnosis and treatment of primarily-multiple gastric cancer, combined with malignant colonic tumors in 27 patients was summarized. One-stage combined radical treatment of the patients is the most effective one.

[Preoperative selective intra-arterial chemotherapy in gastric cancer]. / Predoperatsionnaia izbiratel'naia vnutriarterial'naia khimioterapiia raka zheludka.

Preoperative intraarterial chemotherapy was administered to 69 patients with gastric cancer. In 34 patients the tumor was localized in the antral portion, in 27 in the body of the stomach involving the proximal portion, and in 8 total involvement of the stomach was revealed. Left gastric artery was catheterized in 42 patients, right gastric-omental artery in 27. An original method of "loop" catheterization of celiac artery branches was used permitting a selective probing of gastric arteries proper. For prolonged intraarterial chemotherapy of gastric cancer adriablastin or farmorubicin were used in single dose 30 mg/M2, 5-fluorouracil in dose 500 mg/M2; the cytostatics were infused in 2-3 sessions. Immediate results of intraarterial chemotherapy were assessed by angiography and other instrumental methods of investigation, as well as intraoperatively and by morphometric analysis. In 62.4% of patients significant or total destruction of the tumor was attained, the volumic share of a viable tumor component being 0 to 2.1%. Altogether 95% of patients survived the follow-up of 2 to 30 months.

[Diagnostic accuracy in acute pancreatitis in the prehospital and early hospital stages]. / Tochnost diagnostiki ostrogo pankreatita na dogospitalnom i rannem gospitalnom etape.

The results of the analysis of diagnosis of acute pancreatitis on the basis of studying 3634 case records are presented. Errors in the diagnosis of acute pancreatitis at the prehospital stage were established in 61.9%, at the early hospital stage--in 32.35% of cases, usually in the form of hyperdiagnosis of the disease.

[Informativeness of the methods of early clinical laboratory diagnosis of acute pancreatitis]. / Informativnost' metodov rannei klinicheskoi laboratornoi diagnostiki ostrogo pankreatita.

In 92 patients with acute pancreatitis, the informative value of the available methods for laboratory investigations (general blood analysis, biochemical blood analysis with measurement of the level of total protein, bilirubin, glucose, ALAT, ASAT, amylase activity, amylase activity in the urine) was analysed. The authors consider that the indices studied are rather informative for independent reliable diagnosis of acute pancreatitis and differentiation of its forms.

[Immunologic status in physiological pregnancy]. / Immunologicheskoe obespechenie fiziologicheski protekaiushchei beremennosti.

The levels of T gamma- and T mu-lymphocytes, functional activity of ConA-induced T-suppressors and the concentrations of SP1 and SP3 were determined in 164 normal pregnant women during 8-40 weeks of gestation. It is found that formation of the suppressor dominant is necessary for the immunological maintenance during 8-32 weeks of gestation. This dominant is intended to block superfluous maternal immune response to fetal alloantigens. The formation of such a dominant is evoked by high functional activity of ConA-induced T-suppressors and high levels of T gamma-lymphocytes with immunodeficiency of T mu-cells. Results of correlation analysis have shown a relationship between functional activity of T-suppressors and accumulation of two specific pregnancy proteins. It permits determining physiological role of SP1 and SP3 as natural endogenous immunoregulators of T-suppressors.

[Comparative analysis of pregnancy proteins and regulation of the functional activity of T-suppressors in pregnancy]. / Sravnitel'nyi analiz belkov beremennosti v reguliatsii funktsional'noi aktivnosti T-supressorov pri gestationnom protsesse.

The relationship between the pregnancy specific proteins (SP1, SP3) and the functional activity of ConA-induced T-suppressors has been studied during normal gestation. There were a positive correlation between the activity of T-suppressors and the level of SP1 during 8-28 weeks of gestation; between the activity of T-suppressors and the level of SP3 during 8-36 weeks, especially during 29-36 weeks of gestation. It was shown that a progressive accumulation of these proteins apparently necessary for the formation a suppression's dominant in the condition of the immunoregulatory branches during gestation. These findings suggest that SP1 and SP3 as a natural endogenous immunoregulators may play an important role in reproductive strategy of human gestation.