RESUMEN
Poliomyelitis associated with live strain vaccine is defined as the paralytic form of the acute anterior poliomyelitis related to the vaccine strain. Since these strains behave similarly to the wild-type virus, we can differentiate, epidemiologically, two types of vaccine-associated poliomyelitis: cases in which the patient was vaccinated and cases in which the patient had had contact with vaccinated individuals. We herein present the case of an unvaccinated child, with a clinical picture of an acute anterior poliomyelitis associated with the live strain vaccine, whose brother received the Sabin vaccine 20 days before the onset of the symptoms. Vaccine strain of the type 3 poliovirus was isolated in fecal culture and a presented mutation in nucleotide 472 (C-->U) in the 5' non-coding region, which is strongly related to the higher strain virulence.
Asunto(s)
Transmisión de Enfermedad Infecciosa , Poliomielitis/transmisión , Vacuna Antipolio Oral/efectos adversos , Preescolar , Heces/virología , Humanos , Lactante , Masculino , Poliomielitis/líquido cefalorraquídeo , Poliomielitis/diagnóstico , Poliovirus/aislamiento & purificación , Vacuna Antipolio Oral/administración & dosificaciónRESUMEN
A case of tuberculosis in a pediatric AIDS patient, submitted to bronchoscopy and transbronchial biopsy as a part of chronic pulmonary disease evaluation, is presented. No AFB (acid-fast bacillus) detection was identified by gastric lavage before the bronchoscopy, nevertheless after the bronchoscopic procedure the patient became contagious, and persisted with positive baciloscopy until the 56th day of therapy.
Asunto(s)
Síndrome de Inmunodeficiencia Adquirida , Bronquios/patología , Líquido del Lavado Bronquioalveolar/microbiología , Mycobacterium tuberculosis/aislamiento & purificación , Tuberculosis Pulmonar/diagnóstico , Biopsia con Aguja , Broncoscopía , Niño , Humanos , Masculino , Tuberculosis Pulmonar/microbiologíaRESUMEN
Two cases of congenital malaria due to Plasmodium vivax and Plasmodium falciparum respectively are reported. The children were born in São Paulo and Paraná to mothers from endemic area of malaria. The mothers had malaria during pregnancy. The children were admitted with severe anemia and hepatosplenomegaly. Despite congenital malaria is being considered a rare event it is a preventable disease and these cases should draw attention to the importance of adequate treatment during pregnancy. Clinical manifestations and management of congenital malaria are also discussed.