Benefits of supplemented preterm formulas on insulin sensitivity and body composition after discharge from the neonatal intensive care unit.

OBJECTIVE: To evaluate body composition and fasting insulin level in preterm infants receiving preterm formulas (higher protein plus docosahexaenoic acid) for longer periods compared with a recent historical cohort receiving these formulas for shorter periods. STUDY DESIGN: A total of 95 infants fed preterm formula for 6 months or longer (postdischarge formula group) and 87 infants fed preterm formula only during their hospital stay (hospital formula group) were included in this arm of the study. RESULTS: Bone mineral density, content, and lean mass were not different at 1 year and 2 years. However, in the postdischarge formula group, total fat mass (%) was lower by the second year (19.3% ± 5.3% vs 21.7% ± 4.2%; P < .01), trunk fat was lower by the first year (14.7% ± 5.0% vs 16.9% ± 4.9%; P < .005) and at the second year (14.1% ± 5.7% vs 17.2% ± 4.7%; P < .001), and fasting insulin was lower by the first year (13.2% ± 7.1% vs 17.2% ± 13.6% mIU/L; P = .06) and at the second year (13.6% ± 6.1% vs 26.4% ± 14.2%; P < .001). CONCLUSION: Preterm infants fed formulas enriched with docosahexaenoic acid may have a better subsequent metabolic profile.

Propiedades psicométricas del cuestionario de auto reporte de la calidad de vida KIDSCREEN-27 en adolescentes chilenos / Psychometric properties of the quality of life questionnaire KIDSCREEEN-27 adapted to Chilean adolescents

Se evalúa, las propiedades psicométricas del cuestionario de Calidad de Vida KIDSCREEN-27 adaptado a niños/as y adolescentes chilenos. Participaron 1678 sujetos escolarizados de entre 8 y 18 años. Se evaluó tanto la consistencia interna como indicadores de validez de constructo, discriminante y convergente. El alfa de Cronbach de la escala total como de las distintas dimensiones es superior a 0.70. Los análisis factoriales exploratorio y confirmatorio arrojan evidencia de una estructura similar a la teórica de cinco dimensiones. El instrumento es capaz de discriminar entre hombres y mujeres, así como entre rangos de edad, en diferentes dimensiones. Los resultados permiten decir que el KIDSCREEN-27 presentó coeficientes de fiabilidad y validez aceptables, similares a los de la versión original, permitiendo disponer de un nuevo instrumento que evalúe calidad de vida en Chile y a la vez comparar los resultados obtenidos con otros países que utilicen este instrumento.

The aim of this research was to evaluate the psychometric properties of the quality of life questionnaire KIDSCREEEN-27 adapted to Chilean children and adolescents. The sample was 1678 participants from schools between 8 and 18 years old. The internal consistency and indicators for construct, discriminant and convergent validity was evaluated. Cronbach alphas for total scale and the domains were higher to .70. The exploratory and confirmatory factorial analysis confirmed the five domains proposed in the theoretical structure. The questionnaire was capable of discriminate by gender, as well as among ages, in different domains. In conclusion, results show that the KIDSCREEN-27 presents acceptable coefficients of reliability and validity, similar to those of the original version. This allows Chilean researchers to have a new instrument to evaluate quality of life, and simultaneously to compare their results with other countries that use this instrument.