[Preparations for serodiagnosis of diseases due to causative agents of ixode tick-borne Borreliosis (Lyme disease). Communication 2. Comparative study of recombinant enzyme immunoassay test-systems (rELISA) for serological diagnosis of ixode tick-borne Borreliosis]. / Preparaty dlia serodiagnostiki zabolevanii, vyzyvaemykh vozbuditeliami iksodovykh kleshchevykh borreliozov (bolezn' Laima). Soobshchenie 2. Sravnitel'naia otsenka rekombinantnykh immunofermentnykh test-sistem (rELISA), ispol'zuemykh v serodiagnostike iksodovykh kleshchevykh borreliozov.

One foreign and two Russian recombinant enzyme immunoassay test-systems were comparatively investigated under conditions of an encoded experiment. Sensitivity in the experiment with the Russian test-systems Borreliosis-ELISA-IgG and Lyme Best was 63.8 and 68.8% respectively. As for the test-system Borrelia IgG Recombinant, it was 47.5%. All the test-systems were highly specific (94.4 to 99.5%). The test-systems Lyme Best and Borrelia IgG Recombinant revealed partial cross reactions with sera from patients with systemic lupus erythematosus and leptospirosis.

[Effect of components of virus-containing allantoic fluid on the stability of influenza virus during storage]. / Vliianie komponentov virussoderzhashchei allantoisnoi zhidkosti na ustoichivost' virusa grippa pri khranenii.

Effects of allantoic fluid fractions (isolated by sedimentation and gel chromatography) on inactivation of influenza virus and lipid peroxidation in viral envelopes and phospholipid liposomes indicate the presence of both components with prooxidant effects enhancing inactivation and of endogenous antioxidants stabilizing the viral activity. The hypothesized "lipid" mechanism of inactivation (suggesting activation of lipid peroxidation in viral envelopes followed by inactivation of viral nucleoprotein) permits a satisfactory interpretation of viral material inactivation.