[Effect of the VOLANTIN resilience promotion program on children with an alternative residential system]. / Efectos de la implementación del programa de promoción de la resiliencia "VOLANTÍN" en niños(as) con sistema de cuidados alternativo residencial.

INTRODUCTION: Internationally, there are resilience promotion programs applied to children in residential alterna tive care with favorable results. The application of the resilience promotion program "VOLANTÍN" has shown to be effective in different groups of school-age children, favoring the development of resilience. OBJECTIVE: To describe the results of the implementation of the "VOLANTÍN' program on the level of resilience, self-concept, and emotional symptoms in children aged 7-12 years in resi dential alternative care (foster care). SUBJECTS AND METHOD: descriptive, longitudinal study. The "VO LANTÍN" program was implemented in a sample of 15 foster children between 7-12 years old. The variables measured were the "Escala de Resiliencia Escolar" (ERE), the Piers-Harris Children's Self Concept Scale, the Anxiety Self-report for Children and Adolescents (AANA), and the Children's Depression Inventory (CDI) at the beginning, at the end, and 3 months after the end of the program, and then were analyzed statistically by nonparametric test. RESULTS: At the beginning, the end, and three months after the program implementation, there was a significant increase in the total sco res of ERE (p0.045), subscales "networks-models" (p0.002) and "external resources" (p0.018); and Self-concept (p0.005), subscales "behavior" (p0.045) and "popularity" (p0.03). AANA total scores decreased significantly (p0.004) as well as the subscales "panic/somatic" (p0.025) and "generalized anxiety" (p0.009). CDI scores decreased, but not significantly. CONCLUSION: The application of the resilience promotion program "VOLANTÍN' increased resilience and self-concept scores and decrea sed anxious symptoms in children aged 7-12 years.

Immunophenotyping of Thymic Lymphoma in a Nelore Cow

Thymic lymphoma is a malignant lymphoid neoplasm that affects several species, including cattle. This type of neoplasia can lead to death due to malignant cell infiltration in different organs. The classification of this neoplasm may predict prognosis and response to treatment. Immunophenotyping is one of the ways to perform this classification. There are reports about the performance of immunohistochemistry (IHC) to classify thymic lymphoma only in taurine cattle, therefore the aim of this report is to describe the immunophenotype of a thymic lymphoma in a Nelore cow. Immunostaining was performed with monoclonal antibodies (CD79, CD4 and CD8). The tumor cells showed positive staining only for CD8 T lymphocytes, coinciding with the disease progression, since the T lymphoma type is more aggressive.(AU)

Expresión de óxido nítrico sintetasa en mucosa sinusal de pacientes portadores de sinusitis crónica versus controles / Expression of nitric oxide synthase in sinus mucosa of chronic sinusitis patients vs controls

Introducción: El óxido nítrico producido en las cavidades paranasales juega un importante rol en la fisiología nasal ya que aumenta la frecuencia del batido ciliar, optimiza el barrido mucociliary tiene un efecto bacteriostático y virustático. Diversos estudios muestran que el óxido nítrico nasal exhalado en pacientes con rinosinusitis crónica es significativamente más bajo que en sujetos sanos. Esto podría estar determinado por una alteración en la difusión del óxido nítrico a través de los ostia de drenaje obstruidos o por una menor producción de óxido nítrico por parte de los portadores de rinosinusitis crónica. En este último caso, esto podría corresponder al evento primario en la etiopatogenia de la rinosinusitis crónica. Objetivos: Estudiar y comparar cualitativamente con técnica de inmunohisto-química la expresión de las isoformas e-NOS e I-NOS de la óxido nítrico sintetasa en mucosa sinusal de pacientes con rinosinusitis crónica y pacientes controles, sin patología rinosinusal infecciosa o alérgica. Material y método: Para responder a esta interrogante se realizó un estudio comparativo de casos y controles, con el objetivo de cuantificar con técnica de inmunohistoquímica la expresión de las isoformas endotelial e inducible de la óxido nítrico sintetasa en mucosa sinusal de pacientes con rinosinusitis crónica y pacientes controles sin patología rinosinusal infecciosa o alérgica. Resultados: Ingresan al estudio un total de 11 pacientes. Seis de ellos son el grupo control y 5 con sinusitis crónica. Ambos grupos presentan resultados similares. Conclusión: Los resultados no muestran ninguna diferencia en la expresión de óxido nítrico sintetasa, tanto en su isoforma endotelial como inducible, en la mucosa sinusal de pacientes portadores de rinosinusitis crónica comparado con sujetos sanos.

Introduction. Nitric oxide produced in the paranasal sinuses plays an important role in nasal physiology because it increases ciliary beat frequency, improves mucociliary clearance and has a bacteriostatic and virustatic effect. Several studies have shown that exhaled nasal nitric oxide was substantially lower in chronic sinusitis patients, compared to healthy subjects. This could be determined by altered nitric oxide diffusion through obstructed drainage ostia, or by chronic sinusitis patients having lower nitric oxide production. Aims. To qualitatively compare by immunocytochemistry the expression of the iNOS and eNOS isoforms of nitric oxide synthase in the sinus mucosa of chronic sinusitis patients and control subjects. Materials and methods. A case-control comparative study was carried out in order to compare by immunocytochemistry the expression of inducible and epithelial isoforms of nitric oxide synthase in nasal mucosa of chronic sinusitis patients and control subjects, with no infectious or allergic rhinosinusal pathology. Results. The results show no difference in the expression of the inducible or epithelial isoform of nitric oxide synthase in the nasal mucosa of chronic sinusitis patients as compared to healthy subjects.