[Lamisil in the therapy of foot mycoses]. / Lamizil v terapii mikozov stop.

A new antimycotic drug lamisil (Sandoz, Switzerland) was given as pills to 35 patients with pedal mycosis (23 of them suffered from onychomycosis). Pedal mycosis was cured for 2 weeks, onychomycosis for 12 weeks. In 2 cases the drug was discontinued because of gastrointestinal toxicity. By tolerance and efficacy, lamisil is superior to griseofulvin and nizoral.

[Dark and photosensitized hemolysis of erythrocytes in the presence of dithranol]. / Temnovoi i fotosensibilizirovannyi gemoliz éritrotsitov v prisutstvii ditranola.

Ditranol (1,8-dihydroxy-9-antrone) induced dark lysis of erythrocytes. After irradiation of the cells with UV-light (366 nm UV-A light) in the presence of ditranol (DUVA-effect) the hemolytic effect increases. It has been found that antioxidant butylated hydroxytoluene BHT in the concentration 10(-7) M did not affect the dark lysis, while with increased BHT concentration up to 10(-5) M the hemolytic effect of ditranol was intensified. The presence of BHT in the above concentration under DUVA-effect did not change the velocity of cell lysis. Sodium aside did not affect the dark hemolysis of ditranol, but it inhibited photosensitized hemolysis.

[Experience with the use of an immunoenzyme analysis method in the diagnosis and removal from the rolls of patients with urogenital gonorrhea]. / Opyt primeneniia metoda immunofermentnogo analiza v diagnostike i pri sniatii s ucheta bol'nykh urogenital'noi gonoreei.

A total of 313 patients have been examined with the use of microscopy, cultures, and enzyme immunoassay (EIA) techniques, EIA, a highly sensitive and specific method, has helped cut down the time of the patients' examinations.

[Kanamycin levels in treating patients with acute and subacute gonorrhea]. / Issledovanie kontsentratsii kanamitsina pri lechenii bol'nykh ostroi i podostroi gonoreei.

Kanamycin levels in blood serum were studied during treatment of patients with acute and subacute not complicated gonorrhea. It was concluded that in treatment of gonorrhea kanamycin should be administered intramuscularly in a dose of 1 g every 12 hours or in a dose of 0.5 g every 6 hours, the course dose being 3 g.

[Food allergy in patients with atopic dermatitis studied using the allergen-specific IgE-FAST test]. / Izuchenie pishchevoi allergii u bol'nykh atopicheskim dermatitom s pomoshch'iu allergenspetsificheskogo IgE-FAST testa.

Alimentary allergy has been studied in 16 patients with atopic dermatitis and in 4 ones with common psoriasis (a reference group) by measuring the concentrations of specific and total immunoglobulin E with the 3M IgE fluoroallergosorbent test. The method has proved to be highly sensitive for the detection of IgE-dependent alimentary allergy contributing much to the pathogenesis of atopic dermatitis.

[Morphology and pathogenesis of psoriasis]. / Morfologiia i patogenez psoriaza.

Data from the literature on morphological features of foci of lesions on the skin which is the main target of the pathological process in psoriasis are presented as well as the materials confirming the systemic nature of the disease. The important role of immunopathological responses in the pathogenesis of psoriasis is emphasized. Viruses, congenital defects in the immune regulatory system, cellular membranes of the epidermis, blood and lymph vessels are discussed as possible etiological factors. The morphology of regression of psoriatic foci of lesions under the influence of photochemotherapy is described.