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Genet Mol Res ; 15(4)2016 Nov 03.
Artículo en Inglés | MEDLINE | ID: mdl-27819736

RESUMEN

Sex-linked dwarf (SLD) chickens have been widely used in cross breeding of broilers and laying hens. To study the molecular mechanisms underlying growth hormone receptor (GHR) in SLD chickens, the expression profiles of GHR were measured in three growth related tissues (liver, breast, and thigh) in male and female S2 SLD chickens at seven growth stages (1 day, 3 weeks, 7 weeks, 9 weeks, 11 weeks, 13 weeks, and 15 weeks). Growth curves of body weight were fitted using logistic and Gompertz models. The results show that the inflexion week and inflexion weight in male chickens was earlier than in female chickens. Regarding the expression profiles of GHR, there was no significant difference between tissues at hatching. The expression peaked at 7 weeks and dropped by degrees in muscle tissue; hepatic expression increased with age and was positively correlated with body weight. Taken together, these results would provide a basis for further study on the molecular mechanisms underlying GHR regulation in SLD chickens.


Asunto(s)
Cruzamiento , Pollos/crecimiento & desarrollo , Pollos/genética , Regulación del Desarrollo de la Expresión Génica , Receptores de Somatotropina/genética , Animales , Femenino , Modelos Logísticos , Masculino , Dinámicas no Lineales , Especificidad de Órganos/genética , ARN Mensajero/genética , ARN Mensajero/metabolismo , Receptores de Somatotropina/metabolismo , Aumento de Peso/genética
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