Left ventricular assist devices: physiologic assessment using echocardiography for management and optimization.

Left ventricular assist devices (LVAD) are being deployed increasingly in patients with severe left ventricular dysfunction and medically refractory congestive heart failure of any etiology. The United States Food and Drug Administration (FDA) recently approved the use of the Thoratec Heartmate II (Thoratec Corporation, Pleasanton, CA, USA) for outpatient use. Echocardiography is fundamental during each stage of patient management, pre-LVAD placement, during LVAD placement, for postoperative LVAD optimization and long-term follow-up. We present a pragmatic and systematic echocardiographic approach that serves as a guide for the management of left ventricular assist devices.

Effect of positional changes on inferior vena cava size.

AIM: To study the effect of positional change on inferior vena cava (IVC) diameter. The influence of positional change on IVC size is not well studied. Although the American Society of Echocardiography guidelines for chamber quantification recommend imaging the IVC in the left lateral position, many labs routinely image the IVC from the supine position. METHODS AND RESULTS: Forty-three patients (age 39.5 ± 9.4) with normal echocardiographic findings were studied. Subcostal imaging was used to assess the IVC in the supine and left lateral positions. IVC dimensions, hepatic vein (HV) Doppler and tricuspid regurgitation (TR) jet velocity were measured. IVC systolic and diastolic dimensions were larger in the supine compared with the left lateral position (17.2 ± 4.1 vs. 10.9 ± 4.4 mm, P < 0.001; 16.2 ± 4.5 vs. 9.9 ± 4.4 mm, P < 0.001, respectively). Position had no influence on HV systolic and diastolic peak velocity. (35.4 ± 23.7 vs. 31.8 ± 35.0 cm/s, P = 0.461; 24.2 ± 19.5 vs. 25.4 ± 31.9 cm/s, P = 0.775, respectively). CONCLUSIONS: The IVC dimension is larger in the supine position independent of the cardiac cycle. This may be due to increased intra-abdominal pressure and compression of the IVC by the liver in the left lateral position. HV systolic and diastolic peak Doppler velocities were not influenced by position.

Right ventricular compression observed in echocardiography from pectus excavatum deformity.

Pectus excavatum exists as varying anatomic deformities and compression of the right heart by the chest wall can lead to patient symptoms including dyspnea and chest pain with exertion. Echocardiography can be difficult but is critical to the evaluation and diagnosis of this patient population. Modifying standard views such as biplane transthoracic and 3-D transesophageal views may be necessary in some patients due to limitations from the abnormal anatomy of the deformed anterior chest wall. Apical four-chamber views when seen clearly can usually visualize any extrinsic compression to the right ventricle of the heart.

Subclinical atherosclerosis: evolving role of carotid intima-media thickness.

Cardiovascular risk factors have utility in risk prediction but have limitations in predicting individual risk. Identifying an individual's risk remains a challenge. Emerging technologies such as carotid artery ultrasonography and measures of carotid intima-media thickness (CIMT) may be useful in identifying the susceptible patient who may benefit from more aggressive preventive therapy. This screening test is noninvasive, reproducible, inexpensive, and radiation-free. Recent data have improved our understanding of the application of CIMT as a screening tool for cardiovascular disease. CIMT measurement may place an individual into a higher- or lower-risk category, allowing for appropriate institution of preventive strategies.

Rheumatic tricuspid valve disease: an evidence-based systematic overview.

BACKGROUND AND AIM OF THE STUDY: Right-sided valve abnormalities are less common than their left-sided counterparts. Furthermore, whilst organic rheumatic involvement of the tricuspid valve is not uncommon, it receives less attention than left-sided heart valves. An evidence-based systematic overview was carried out to assess the epidemiology, diagnosis and management of organic rheumatic tricuspid valve disease (RTVD) over the past half century. METHODS: A computed search spanning more than four decades was conducted to identify articles on various aspects of RTVD. The bibliographies of all relevant articles were also searched. RESULTS: A total of 2,497 rheumatic heart disease patients (mean age 25.5 years; female:male ratio 1.3:1) was included. RTVD was detected in 193 patients (7.7%). Echocardiography was used to detect tricuspid valve involvement in all patients. Associated mitral valve disease was present in 99.3% of the patients with RTVD. A total of 1,092 patients (mean age 45.4 years) was included from six studies on surgical correction of the tricuspid valve. Of these patients, 278 (25.4%) underwent tricuspid valve replacement, while 814 (74.5%) had tricuspid valve repair. The in-hospital mortality was 9.9%, and late mortality 33.2% CONCLUSION: RTVD is not uncommon among patients with rheumatic heart disease, but attracts less attention and might, therefore, be overlooked. Echocardiography is the most common diagnostic tool. Although indications for surgical intervention are not well defined, valve repair may have a better outcome than replacement.

Fatal migratory pulmonary thromboembolism following successful pericardiocentesis.

Echocardiography-guided pericardiocentesis is relatively safe with minimal risk in experienced hands. However, complications can occur because of the procedure. This report describes a unique case of an 84-year-old man with unanticipated fatal pulmonary thromboembolism following a successful pericardiocentesis.

Critical appraisal on the utility of echocardiography in the management of acute pulmonary embolism.

Echocardiography can be used for rapid and accurate risk stratification of patients with pulmonary embolism to appropriately direct the therapeutic strategies for those at high risk. Echocardiography is an ideal risk stratification tool in this regard because of its easy portability to the emergency room or to the bed side. It can be performed at a relatively low cost and at no risk to the patient. Furthermore, echocardiography allows repetitive noninvasive assessment of the cardiovascular and hemodynamic status of the patient and the response to the therapeutic interventions. Right ventricular hypokinesis, persistent pulmonary hypertension, a patent foramen ovale, and a free floating right heart thrombus are echocardiographic markers that identify patients at a higher risk for morbidity and mortality. Such patients warrant special consideration for thrombolysis or embolectomy.

Evaluation of right ventricular global and regional function during stress echocardiography using novel velocity vector imaging.

AIMS: This study tested the feasibility of velocity vector imaging (VVI) analysis to quantitatively assess right ventricular (RV) function during stress echocardiography (SE). METHODS AND RESULTS: We prospectively enrolled 73 patients (treadmill 38, dobutamine 35) undergoing SE using an Acuson C512 ultrasound system. The RV ejection fraction was measured for global RV function. The radial velocity, circumferential strain, and strain rate (SR) of four segments from the mid-level RV short-axis view, and the longitudinal velocity, strain, and SR of six segments from the RV apical four-chamber view were used to evaluate regional RV function. The VVI analysis successfully in 70 of 73 cases (96%). Fifty (71%) of the 70 demonstrated a normal response to stress, showing an increased RV ejection fraction (P < 0.001), and longitudinal velocity and SR in the basal lateral walls at peak stress (7.7 +/- 2.0-10.3 +/- 2.9 cm/s, -1.9 +/- 0.7 to -3.2 +/- 1.4/s, P < 0.001); the longitudinal displacement and strain of the same segment did not show a significant increase. CONCLUSION: Quantitative assessment of global and regional RV function during SE was feasible using VVI analysis. Longitudinal velocity and SR of the RV basal lateral wall were significantly better than longitudinal displacement or strain for detecting RV response during SE.

Liquefaction necrosis of calcified mitral annulus.

Echogenicity within the left atrioventricular groove can be due to many conditions, such as mitral annular calcification, abscess, dilated coronary sinus, and aneurysm of the left circumflex coronary artery. However, in a patient who has no systemic symptoms, a bright, round echodensity with central echolucency and smooth borders in the mitral annulus is characteristic of liquefaction necrosis of a calcified mitral annulus. We report the occurrence of this rare manifestation in a 60-year-old patient who presented with myocardial infarction.