RESUMEN
INTRODUCTION: Feeding mixed rations is a widely used practice for cattle to ensure the intake of a balanced diet and to reduce competition for food. It is unknown, whether mixed rations have the same advantages for small ruminants because they differ from cattle in their feeding and social behaviour. In this observational pilot study, an array of feeding and social behaviour of dairy goats and sheep fed ad libitum with mixed rations on Swiss farms was investigated. Twelve dairy goat and 12 dairy sheep farms feeding mixed rations were visited once during the winter feeding period. Data on the feeding management, feeding place design and the composition of the mixed rations were collected. The number of animals feeding simultaneously and the number and type of agonistic interactions during feeding were assessed by direct observations for 6 hours after the morning feed-distribution. The feeding management and the composition of the mixed rations were very heterogeneous among farms. The feed rations were mostly well balanced in relation to energy and protein and covered the requirements for the daily production of about 2,5 kg of milk. In terms of feeding simultaneously, sheep were more synchronous than goats. The mean number of agonistic interactions per feeding place within 6 hours were 3,8 in goats and 1,8 in sheep; thus, the probability to observe agonistic behaviour is higher in goats than in sheep. Goats and sheep also differed in the frequency of types of agonistic interactions. Overall, the occurrence of agonistic interactions between animals during feeding decreased with higher numbers of feeding places per animal and longer periods of time since the feed distribution. To conclude, when feeding mixed rations, agonistic interactions related to feeding are more frequent in goats but also occur in sheep to a considerable extent. They can be decreased by offering more feeding places.
INTRODUCTION: L'alimentation avec des rations mixtes est une pratique largement utilisée pour les bovins afin de garantir l'apport d'une alimentation équilibrée et de réduire la concurrence pour la nourriture. On ignore si les rations mixtes présentent les mêmes avantages pour les petits ruminants, car ils diffèrent des bovins en matière de comportement alimentaire et social. Dans cette étude observationnelle pilote, un éventail de comportements alimentaires et sociaux de chèvres et de moutons laitiers nourris ad libitum avec des rations mixtes dans des fermes suisses a été étudié. Douze exploitations de chèvres laitières et 12 exploitations de moutons laitiers, utilisant des rations mixtes, ont été visitées une fois pendant la période d'alimentation hivernale. Des données sur la gestion de l'alimentation, la conception du lieu d'alimentation et la composition des rations mixtes ont été recueillies. Le nombre d'animaux s'alimentant simultanément et le nombre et le type d'interactions agonistiques pendant l'alimentation ont été évalués par des observations directes pendant 6 heures après la distribution matinale des aliments. La gestion de l'alimentation et la composition des rations mélangées étaient très hétérogènes entre les exploitations. Les rations alimentaires étaient généralement bien équilibrées en termes d'énergie et de protéines et couvraient les besoins pour la production quotidienne d'environ 2,5 kg de lait. En termes d'alimentation simultanée, les moutons étaient plus synchrones que les chèvres. Le nombre moyen d'interactions agonistiques par place d'alimentation dans les 6 heures était de 3,8 chez les chèvres et de 1,8 chez les moutons ; la probabilité d'observer un comportement agonistique est en conséquence plus élevée chez les chèvres que chez les moutons. Les chèvres et les moutons diffèrent également dans la fréquence des types d'interactions agonistiques. Dans l'ensemble, l'occurrence des interactions agonistiques entre les animaux pendant l'alimentation a diminué avec un nombre plus élevé de places d'alimentation par animal et des périodes plus longues depuis la distribution des aliments. En conclusion, lors de la distribution de rations mixtes, les interactions agonistiques liées à l'alimentation sont plus fréquentes chez les chèvres mais se produisent également dans une large mesure chez les moutons. Elles peuvent être réduites en offrant davantage de places d'alimentation.
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Conducta Agonística , Cabras , Animales , Bovinos , Granjas , Proyectos Piloto , Ovinos , SuizaRESUMEN
INTRODUCTION: Husbandry conditions for rabbits in Switzerland are at a high animal welfare level in international comparison. Wire mesh flooring is prohibited and group housing is mandatory up to the age of eight weeks. Despite these animal-friendly husbandry standards, animal losses seem to be a significant problem, although reliable data on professional Swiss meat rabbit production is lacking to date. A herd survey was carried out in 52 rabbit farms to address this situation. At the same time, each new litter and each fattening group was documented with a standardized form focusing on animal death and the use of medication by the farmer over a one year period. In the case of increased mortality or new health problems, dead rabbits were sent to the National Reference Center for Poultry and Rabbit Diseases (Zurich) for pathological examination including bacteriological and parasitological diagnostics. Data from 32 farms were evaluated. The average mortality of young animals (birth to weaning) was 14.9% (1.0-30.0%) and of fattening rabbits (weaning to slaughter) 17.3% (4.3-31.8%). Intestinal diseases, mainly dysentery, intestinal coccidiosis and mucoid enteropathies, were the primary cause of death (68.2%). Eimeria spp., Escherichia coli and Clostridium perfringens were identified as the most frequent pathogens. Respiratory diseases were found in 18.7% of the examined rabbits, with Pasteurella multocida identified as the most common pathogen. 60.0% of the farms used antibiotics during the study period and a third (34.7%) of all the fattening animals were medicated with at least one antibiotic. The present results confirm that despite high animal welfare standards infectious diseases and mortality rates represent a considerable problem in professional Swiss meat rabbit production. Risk factors of increased morbidity and mortality should be identified to improve rabbit health, to reduce the high mortality rate and the extensive use of antibiotics in professional Swiss meat rabbit production. Practicable management improvements with specific prevention strategies should be developed.
INTRODUCTION: Les conditions d'élevage des lapins en Suisse sont d'un niveau élevé en comparaison internationale. Il est interdit de les garder sur un sol en treillis métallique et leur détention en groupe est obligatoire jusqu'à l'âge de huit semaines. Malgré ces normes d'élevage respectueuses des animaux, les pertes d'animaux semblent être un problème important, les données fiables sur la production professionnelle suisse de lapins de boucherie faisant largement défaut à ce jour. Afin de remédier à cette situation, une enquête d'exploitation a été réalisée dans 52 élevages cunicoles. En parallèle, chaque nouvelle portée et chaque groupe d'engraissement était documenté par le chef d'élevage avec un formulaire standardisé au cours d'une année, l'accent étant principalement mis sur les pertes d'animaux et l'utilisation de médicaments. En cas d'augmentation de la mortalité ou de nouveaux problèmes de santé, les lapins morts étaient envoyés au Centre national de référence pour les maladies de la volaille et des lapins (Zurich) pour une autopsie comprenant des examens bactériologiques et parasitologiques. Les données de 32 entreprises ont pu être évaluées. La mortalité moyenne des jeunes animaux (de la naissance au sevrage) était de 14,9% (1,030,0%), celle des lapins à l'engrais (du sevrage à l'abattage) était de 17,3% (4,3 31,8%). Les maladies intestinales ont été retrouvées en premier lieu (68,2%), principalement la dysenterie, suivie par la coccidiose intestinale et les entéropathies mucoïdes. Eimeria spp., Escherichia coli et Clostridium perfringens ont été identifiés comme les agents pathogènes les plus fréquents par ordre décroissant. Des maladies respiratoires ont été trouvées chez 18,7% des lapins examinés, le pathogène le plus courant étant Pasteurella multocida. 60,0% des élevages examinés ont utilisé des antibiotiques au cours de la période d'étude, environ un tiers (34,7%) de tous les processus d'engraissement examinés ont été traités avec au moins un antibiotique. Les résultats confirment que les maladies infectieuses et les pertes de lapins en Suisse représentent un problème considérable dans l'élevage professionnel malgré un élevage respectueux des animaux. Afin d'améliorer la santé des lapins dans les entreprises de production professionnelles suisses et de réduire ainsi les taux de mortalité élevés et l'utilisation intensive d'antibiotiques, les facteurs de risque d'augmentation de la morbidité et de la mortalité doivent être déterminés dans une étape supplémentaire afin de développer des améliorations de gestion réalisables dans le cadre de stratégies de prévention spécifiques.
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Crianza de Animales Domésticos , Carne , Bienestar del Animal , Animales , Granjas , Conejos , SuizaRESUMEN
BACKGROUND: Between February and April 2016, a slight increase in mortality was observed in a colony consisting of 400 captive Seba's short-tailed bats (Carollia perspicillata). These animals cohabited with other nocturnal animal species in a dome of a private zoo in Switzerland. RESULTS: Gross and histological analysis of two (14.3%) out of the 13 animals submitted for necropsy within this period revealed a necrosuppurative pneumonia, hepatitis, splenitis, enterocolitis, and endometritis, with abundant intralesional colonies of Gram-negative rods. Yersinia (Y.) pseudotuberculosis serotype O:1 and biotype 1 belonging to the sequence type ST90 was isolated from the affected organs in both animals. Following this diagnosis, » of the colony (99 animals) was culled and submitted for gross and histopathological analysis, and a bacterial culture selective for Yersinia spp. of lung, liver, and spleen was performed. From these 99 animals, one gravid female was tested and found to be positive for Y. pseudotuberculosis in the absence of clinical symptoms and histopathological lesions. PCR analysis of altogether three bacterial isolates for virulence factors revealed the presence of the ail gene, and one isolate was also positive for the virF and yadA plasmid genes. CONCLUSIONS: These findings suggest that Carollia perspicillata are susceptible to lethal yersiniosis but do not represent a regular reservoir for Y. pseudotuberculosis. Culling of » of the population was sufficient to limit the spread of this infection among the colony. Moreover, no infections were detected in cohabitant nocturnal animals and caretakers, indicating that the zoonotic risk in this case was low.
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Quirópteros/microbiología , Infecciones por Yersinia pseudotuberculosis/veterinaria , Yersinia pseudotuberculosis/aislamiento & purificación , Animales , Animales de Zoológico/microbiología , Femenino , Masculino , Embarazo , Serogrupo , Suiza , Infecciones por Yersinia pseudotuberculosis/epidemiologíaRESUMEN
OBJECTIVES: To evaluate 12-month treatment patterns, healthcare resource use (HCRU), and costs for patients with rheumatoid arthritis (RA), following initiation of index TNF inhibitors (TNFi) and subsequent biologic DMARDs (bDMARDs). METHODS: This was a retrospective cohort analysis of adults with RA newly initiating TNFi in the Truven Marketscan Commercial Claims and Encounters and Medicare Supplemental Databases during 2010-2013. A sub-group of patients who switched to a bDMARD within 12 months post-index and within 180 days of last index TNFi were subsequently evaluated over 12 months. TNFi/bDMARD treatment patterns were characterized as: continuers, no gap >180 days in prescription/administration of index TNFi; discontinuers, gap >180 days; switchers, initiated new bDMARD. Concomitant conventional synthetic DMARD use, co-morbid chronic illnesses, and RA severity were assessed. All-cause/RA-related HCRU and costs were evaluated 12 months post-index. RESULTS: Of 9567 identified patients, 67.2%, 17.3%, and 15.4% were continuers, discontinuers, and switchers, respectively. Switchers had the highest 12-month unadjusted mean all-cause costs of $34,585 vs $33,051 for continuers (p = 0.1158) and $24,915 for discontinuers (p < 0.0001; discontinuers vs continuers, p < 0.0001). RA-related costs comprised 82.8%, 31.4%, and 85.7% of total costs for continuers, discontinuers, and switchers, respectively. Of 764 switchers, 68.2% switched to alternative TNFi (cyclers), the rest to non-TNFi bDMARDs; 36.7% of patients who switched to TNFi switched again (to third-line bDMARD) vs 27.6% (p = 0.0313) of those who switched to non-TNFi bDMARDs. Switchers to non-TNFi bDMARDs had higher mean 12-month all-cause costs of $76,580 compared with $50,689 for switchers to alternative TNFi (p < 0.0001); biologic-administration visits comprised 78.8% of the greater total RA-related costs of switchers to non-TNFi bDMARDs. CONCLUSIONS: Real-world TNFi discontinuation/switching rates correspond to randomized controlled trial non-response rates. TNFi cycling is common and associated with an increased likelihood of switching to third-line bDMARD. Switching to non-TNFi bDMARDs was associated with higher costs, mostly attributed to in-office administrations.
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Antirreumáticos/uso terapéutico , Artritis Reumatoide/tratamiento farmacológico , Factor de Necrosis Tumoral alfa/antagonistas & inhibidores , Anciano , Femenino , Humanos , Masculino , Persona de Mediana Edad , Estudios Retrospectivos , Resultado del Tratamiento , Factor de Necrosis Tumoral alfa/uso terapéuticoRESUMEN
In Switzerland postweaning multisystemic wasting syndrome (PMWS), caused by porcine circovirus type 2, was detected for the first time in 2001. To comprise the PMWS epizooty in 2003 - 2006 retrospectively, individual animals were diagnosed according to internationally accepted criteria and temporal and regional patterns of the epizooty were reconstructed. Occurrence of PMWS was predominantly in regions with a high frequency of swine farms (central and eastern Switzerland). Apparently it was spread to other, less affected regions, through trade of infected fattening pigs. Concurrently, disease was found in different establishments of production. Affected were mainly weaners or fattening pigs. In 40 % of the breeding farms and in 25 % of the fattening farms mortality rate was higher than 5 %. Starting in 2003, also a higher frequency of porcine dermatitis and nephropathy syndrome (PDNS) diseased pigs was diagnosed. In the years 2004 to 2006 they accounted for about 10 % of the diagnosed PCV2-associated diseases. Besides the characteristic skin- and kidney lesions approximately half of the PDNS cases showed wasting and lymphoid lesions with high quantities of PCV2 antigen. We termed these mixed forms PMWS-PDNS-hybrid forms.
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Dermatitis/veterinaria , Síndrome Multisistémico de Emaciación Posdestete Porcino/epidemiología , Enfermedades de los Porcinos/epidemiología , Animales , Porcinos , Suiza/epidemiologíaRESUMEN
Leiomyosarcoma was diagnosed in the heart of a 3-year-old female guinea pig. Neoplastic tissue was located in the ventricular septum extending into the right ventricular lumen, but was not obvious grossly. Microscopically, the mass was nodular and infiltrative and was composed of streams and bundles of spindle cells. Immunohistochemically, the neoplastic cells expressed vimentin and α-smooth muscle actin. There was no cross striation of the muscle cells. This is the first report of cardiac leiomyosarcoma in a guinea pig.
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Neoplasias Cardíacas/veterinaria , Leiomiosarcoma/veterinaria , Actinas/metabolismo , Animales , Biomarcadores de Tumor/metabolismo , Femenino , Cobayas , Neoplasias Cardíacas/metabolismo , Neoplasias Cardíacas/patología , Inmunohistoquímica/veterinaria , Leiomiosarcoma/metabolismo , Leiomiosarcoma/patología , Tabique Interventricular/metabolismo , Tabique Interventricular/patología , Vimentina/metabolismoRESUMEN
The present case report describes a novel etiological agent of cutaneous leishmaniasis that appears for the first time in a cow. A similar agent had recently been described as causing autochthonous infections in horses of Germany and Switzerland. The infection in the cow was initially diagnosed upon clinical and immunohistological findings. Subsequent comparative sequence analysis of diagnostic PCR products from the internal transcribed spacer 1 (ITS1) of ssrRNA classified the respective isolate as neither Old World nor New World Leishmania species, but yielded complete identity of the analysed sequence with the above mentioned horse cases and 98% identity to Leishmania sp. siamensis, an organism recently identified in a visceral leishmaniasis patient from Thailand. The potential transmitting vectors for all these cases have not yet been identified. Future investigations will have to elucidate the veterinary-epidemiological relevance of this etiological agent, as well as biological parameters such as transmission mode and geographical origin and distribution.
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Enfermedades de los Bovinos/diagnóstico , Leishmania/aislamiento & purificación , Leishmaniasis Cutánea/veterinaria , Animales , Bovinos , Enfermedades de los Bovinos/parasitología , Enfermedades de los Bovinos/patología , Leishmaniasis Cutánea/diagnóstico , Leishmaniasis Cutánea/patología , SuizaRESUMEN
A 13-year-old male intact Golden Retriever was presented for chronic regurgitation and vomitus. The only clinical abnormality was halitosis, a neurological examination was normal. Thoracic radiography revealed a moderately distended, air-filled esophagus and a presumptive diagnosis of idiopathic megaesophagus was made. No other disorder causing abnormal esophageal motor function could be identified. As supportive and anticholinergic therapy failed to improve the dogs condition and ongoing regurgitation worsened, owners opted for euthanasia. Postmortem examination revealed a small (1.5 cm diameter) mass in the terminal esophagus. Microscopically a leio-myoma with mild multifocal mixed-cell esophagitis was diagnosed. This report illustrates how a potentially curable disease such as leiomyoma can clinically mimic acquired idiopathic megaesophagus and emphasizes that additional diagnostic procedures (contrast study, esophagoscopy) can be indicated in individual cases.
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Enfermedades de los Perros/diagnóstico , Acalasia del Esófago/veterinaria , Neoplasias Esofágicas/veterinaria , Esofagitis/veterinaria , Leiomioma/veterinaria , Animales , Diagnóstico Diferencial , Enfermedades de los Perros/etiología , Perros , Acalasia del Esófago/diagnóstico , Acalasia del Esófago/etiología , Neoplasias Esofágicas/complicaciones , Neoplasias Esofágicas/diagnóstico , Esofagitis/complicaciones , Esofagitis/diagnóstico , Halitosis/etiología , Halitosis/veterinaria , Reflujo Laringofaríngeo/etiología , Reflujo Laringofaríngeo/veterinaria , Leiomioma/complicaciones , Leiomioma/diagnóstico , Masculino , Vómitos/etiología , Vómitos/veterinariaRESUMEN
This case report describes the clinical, ultrasonographic and postmortem findings in an alpaca with Mycobacterium kansasii infection. The alpaca was referred because of chronic weight loss and weakness. The results of clinical examination, haematology and serum biochemistry were not diagnostic. Ultrasonography of the liver revealed multiple, hyperechogenic lesions with a diameter of 1 to 3 cm. Histological evaluation of a liver biopsy sample showed acute, multifocal, suppurative, necrotising hepatitis. Despite treatment with antibiotics, the alpaca died. Postmortem examination revealed nodular to coalescing lesions in the liver, lungs, mediastinum, pleura and greater omentum, which could not be differentiated macroscopically or histologically from lesions caused by tuberculosis. Ziehl-Neelsen staining showed massive numbers of rods within epithelioid macrophages, which were identified as Mycobacterium kansasii by polymerase chain reaction analysis.