Risk of postoperative venous thromboembolism after minimally invasive surgery for endometrial and cervical cancer is low: a multi-institutional study.

OBJECTIVE: To determine the 30-day prevalence of venous thromboembolism (VTE) after minimally invasive surgery (MIS) for endometrial (EC) and cervical cancers (CC). METHODS: A retrospective cohort study at two large tertiary care centers between 2006 and 2011. Patients having MIS for EC or CC were included. Cases converted to laparotomy were excluded. The primary outcome measure was clinically diagnosed VTE within 30 days of operation. RESULTS: Of the 558 patients, 90% had EC and 10% had CC. Modalities of hysterectomy included robotic (88%), vaginal (9%), and laparoscopic (3%). A total of 66% had pelvic and 35% had paraaortic lymphadenectomy. The VTE prophylaxes were sequential compression devices (100%) and heparin (39%). There were no VTE events during hospital stay (95% CI, 0.0%-0.7%). The 30-day prevalence of VTE was (0.5%; 95% CI, 0.1%-1.6%). The hitherto recommended risk criteria for giving extended 30-day thromboprophylaxis by the American College of Obstetrics and Gynecologists (ACOG) or by the American Society of Clinical Oncology (ASCO) did not predict risk of VTE in our population. CONCLUSIONS: The prevalence of VTE in EC and CC undergoing MIS is very low. The existing 30-day risk prediction models proposed by the ACOG and ASCO stem from open surgery patients and do not appear to apply to MIS patients. Certainly, we found no evidence supporting the use of extended prophylactic heparin in this setting. Further research is urgently needed to define the role of any duration of thromboprophylaxis in MIS patients with endometrial or cervix cancer.

Gestational diabetes insipidus, HELLP syndrome and eclampsia in a twin pregnancy: a case report.

We report a case of eclampsia in a twin pregnancy complicated by HELLP syndrome and diabetes insipidus. This confluence of disease processes suggests that a modification of common magnesium sulfate treatment protocols may be appropriate in a certain subset of patients.

Serous cystadenoma with omental caking and ovarian torsion: an unusual case presentation.

BACKGROUND: This case evaluates a patient with abdominal pain who presented with a pelvic mass and imaging studies suspicious for malignancy. CASE: A 21-year-old, gravida 0, para 0, was admitted after presenting to the outpatient with abdominal pain. Ultrasound revealed a large 17 x 20 cm pelvic mass with solid and cystic components. CT scan revealed worrisome findings including the finding of "omental caking" and nodal enlargement. CA 125 was elevated at 85 U/ml. Final pathology after surgical removal of the mass showed evidence of serous cystadenoma with ovarian torsion without signs of malignancy. The patient had an unremarkable postoperative course and was discharged in stable condition. CONCLUSION: Although uncommon, pelvic masses that are benign may mimic malignant masses with extradnexal inflammation.