Exploring Phytochemical Profile, Pharmaceutical Activities, and Medicinal and Nutritional Value of Wild Edible Plants in Ethiopia.

In many parts of the world, wild edible plants (WEPs) constitute an essential component of the global food basket, providing an alternative source of wholesome and nourishing food. Ethiopia is one of countries of the world having largest concentrations of WEPs. In the country, various parts of WEPs, such as fruits, stems, leaves, tubers, roots, or entire plant sections, are frequently consumed and used as food sources for famine relief during seasonal food shortages, as well as for commercial purposes. WEPs have been also used in the country as sources of phytochemicals, traditional medicine, and pharmaceutical applications. Approximately 30%-40% of WEPs and over 413 different kinds of WEPs are commonly consumed by Ethiopians regularly. Most plant families utilized as WEPs are Moraceae, Fabaceae, Flacourtiaceae, Myrtaceae, Rosaceae, and Tiliaceae. The most widely used plant parts of WEPs were fruits. WEPs can be used as substitutes for traditional plant-based human diets because of their high nutritional value, which includes proteins, vitamins B2 and C, and low moisture content. This review focuses on using edible wild plants for pharmacological purposes, dietary supplements, and alternative medicine. Many obstacles prevent people from consuming WEPs, even when they are easily accessible and available. The use of WEPs must be encouraged by nutrition policies as one of the pillars of food and nutrition security. To increase yield, diversify the revenue streams of small-scale farmers, and protect the diminishing wild edible fruit resources, it is imperative to domesticate and enhance WEPs.

Synthesis of carboxylated cellulose nanocrystal/ZnO nanohybrids using Oxytenanthera abyssinica cellulose and zinc nitrate hexahydrate for radical scavenging, photocatalytic, and antibacterial activities.

The extremely low antioxidant, photocatalytic, and antibacterial properties of cellulose limit its application in the biomedical and environmental sectors. To improve these properties, nanohybrides were prepared by mixing carboxylated cellulose nanocrystals (CCNCs) and zinc nitrate hexahydrate. Data from FTIR, XRD, DLS, and SEM spectra showed that, ZnO nanoparticles, with a size ranging from 94 to 351 nm and the smallest nanoparticle size of 164.18 nm, were loaded onto CCNCs. CCNCs/ZnO1 nanohybrids demonstrated superior antibacterial, photocatalytic, and antioxidant performance. More considerable antibacterial activity was shown with a zone of inhibition ranging from 26.00 ± 1.00 to 40.33 ± 2.08 mm and from 31.66 ± 3.51 to 41.33 ± 1.15 mm against Gram-positive and Gram-negative bacteria, respectively. Regarding photodegradation properties, the maximum value (∼91.52 %) of photocatalytic methylene blue degradation was observed after 75 min exposure to a UV lamp. At a concentration of 125.00 µm/ml of the CCNC/ZnO1 nanohybrids sample, 53.15 ± 1.03 % DPPH scavenging activity was obtained with an IC50 value of 117.66 µm/ml. A facile, cost-effective, one-step synthesis technique was applied to fabricate CCNCs/ZnO nanohybrids at mild temperature using Oxytenanthera abyssinica carboxylated cellulose nanocrystals as biotemplate. The result showed that CCNCs/ZnO nanohybrids possess potential applications in developing advanced functional materials for dye removal and antibacterial and antioxidant applications.

Experimental investigations on PVA/chitosan and PVA/chitin films for active food packaging using Oxytenanthera abyssinica lignin nanoparticles and its UV-shielding, antimicrobial, and antiradical effects.

This study investigated the effect of adding lignin nanoparticles (LNPs) derived from Oxytenanthera abyssinica via alkali-acid nanoprecipitation method to polyvinyl alcohol/chitosan (PVA/CI) and polyvinyl alcohol/chitin (PVA/CH) films for the active food packaging applications. Adding LNPs at concentrations of 1 % and 3 % improved the films' thermal stability and mechanical properties. The lowest water solubility and moisture content were observed in PVA/CI/LNPs films. LNPs exhibited effective 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activities, with the highest values observed in PVA/CH/LNPS and PVA/CI/LNPS films with values of 87.47 and 88.74 % respectively. The addition of LNPs also improved the UV-blocking abilities of the films. PVA/CH/LNP3 and PVA/CI/LNP3 have the smallest percentage transmission values of 3.34 % and 0.86 % in the UV range. The overall migration of dietary stimulants was lower in PVA/CI/LNPS and PVA/CH/LNPS films compared to PVA film. Antibacterial tests demonstrated the inhibitory capacity of the synthesized biofilms against both gram-positive and negative bacterial species, with the highest inhibitory value of 26 mm. The study suggests that PVA/CH/LNPS and PVA/CI/LNPS films have potential applications as active food packaging materials and can be explored in other potential applications such as drug delivery, tissue engineering, wound healing, and slow-release urea fertilizer development.

Agricultural Residues as Raw Materials for Pulp and Paper Production: Overview and Applications on Membrane Fabrication.

The need for pulp and paper has risen significantly due to exponential population growth, industrialization, and urbanization. Most paper manufacturing industries use wood fibers to meet pulp and paper requirements. The shortage of fibrous wood resources and increased deforestation are linked to the excessive dependence on wood for pulp and paper production. Therefore, non-wood substitutes, including corn stalks, sugarcane bagasse, wheat, and rice straw, cotton stalks, and others, may greatly alleviate the shortage of raw materials used to make pulp and paper. Non-woody raw materials can be pulped easily using soda/soda-AQ (anthraquinone), organosolv, and bio-pulping. The use of agricultural residues can also play a pivotal role in the development of polymeric membranes separating different molecular weight cut-off molecules from a variety of feedstocks in industries. These membranes range in applications from water purification to medicinal uses. Considering that some farmers still burn agricultural residues on the fields, resulting in significant air pollution and health issues, the use of agricultural residues in paper manufacturing can eventually help these producers to get better financial outcomes from the grown crop. This paper reviews the current trends in the technological pitch of pulp and paper production from agricultural residues using different pulping methods, with an insight into the application of membranes developed from lignocellulosic materials.

Prevention and Treatment of Cardiovascular Diseases with Plant Phytochemicals: A Review.

Cardiovascular diseases (CVDs) are the world's leading killers, accounting for 30% deaths. According to the WHO report, CVDs kill 17.9 million people per year, and there will be 22.2 million deaths from CVD in 2030. The death rates rise as people get older. Regarding gender, the death rate of women by CVD (51%) is higher than that of men (42%). To decrease and prevent CVD, most people rely on traditional medicine originating from the plant (phytochemicals) in addition to or in preference to commercially available drugs to recover from their illness. The CVD therapy efficacy of 92 plants, including 15 terrestrial plants, is examined. Some medicinal plants well known to treat CVD are, Daucus carota, Nerium oleander, Amaranthus Viridis, Ginkgo biloba, Terminalia arjuna, Picrorhiza kurroa, Salvia miltiorrhiza, Tinospora cordifolia, Mucuna pruriens, Hydrocotyle asiatica, Bombax ceiba, and Andrographis paniculate. The active phytochemicals found in these plants are flavonoids, polyphenols, plant sterol, plant sulphur compounds, and terpenoids. A general flavonoid mechanism of action is to prevent low-density lipoprotein oxidation, which promotes vasodilatation. Plant sterols prevent CVD by decreasing cholesterol absorption in the blood. Plant sulphur compound also prevent CVD by activation of nuclear factor-erythroid factor 2-related factor 2 (Nrf2) and inhibition of cholesterol synthesis. Quinone decreases the risk of CVD by increasing ATP production in mitochondria while terpenoids by decreasing atherosclerotic lesion in the aortic valve. Although several physiologically active compounds with recognized biological effects have been found in various plants because of the increased prevalence of CVD, appropriate CVD prevention and treatment measures are required. More research is needed to understand the mechanism and specific plants' phytochemicals responsible for treating CVD.