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ObjectiveTo explore the psychological defense styles and family environment among male prisoners of different terms of imprisonment, and to analyse the relationship between their psychological defense styles and family environment. MethodsA total of 200 male prisoners in a prison in Guangdong were randomly selected from April to June 2015, and they were classified into less than 5 years of imprisonment group (n=108) and 5 years or more imprisonment group (n=92). Their defense style and family environment were evaluated by Defense Style Questionnaire (DSQ) and Family Environment Scale-Chinese Version (FES-CV). Pearson correlation analysis was used to test the correlation between each scale score. ResultsThe factor scores of immature defense mechanism and intermediate defense mechanism of DSQ in the group with less than 5 years of imprisonment were lower than those in the group with 5 years or more imprisonment, with statistically significant differences (t=4.198, 1.137, P<0.01). The scores of FES-CV family intimacy, emotional expression and organizational factors in less than 5 years of imprisonment group were higher than those in 5 years or more imprisonment group (t=3.122, 2.993, 2.203, P<0.01), and the scores of contradiction factors were lower than those in 5 years or more imprisonment group (t=-3.682, P<0.01). The scores of DSQ immature, intermediate defense mechanism and concealment factor of male prisoners were negatively correlated with the scores of FES-CV family intimacy and emotional expression factor (r=-0.428~-0.172, P<0.05 or 0.01), and the scores of 4 factors in DSQ were all positively correlated with the scores of contradiction factor in FES-CV (r=0.175~0.384, P<0.05 or 0.01). ConclusionCompared with male prisoners with less than 5 years of imprisonment, those with 5 years or more are prone to adopt immature and intermediate defense mechanisms, and their family environments are characterized by apparent contradiction and a lack of family intimacy, emotional expression and organization. Furthermore, the defects of psychological defense mechanism of prisoners are related to their family environment.
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Sixty-two patients with type 2 diabetes were treated with acarbose combined intensive insulin therapy( combined intensive group)or intensive insulin therapy alone (simple intensive group).As the blood glucose control reached the target,the mean amplitude of glycaemic excursion (MAGE),the absolute difference between the mean of daily differences ( MODD ),and standard deviation of blood glucose (SDBG) in combined intensive group were lower than those in simple intensive group [ ( 3.76 ± 1.47 vs 6.52 ± 1.57 ) mmol/L,( 0.57 ±0.49 vs 1.10 ±0.69 )mmol/L,( 1.44±0.60 vs 2.42±0.92 ) mmol/L,all P<0.01 ].Daily mean blood glucose (MBG) of the former group was better than that of the latter group [ (7.08±0.69 vs 8.27 ± 1.31 ) mmol/L,P<0.01 ].By the end of treatment,HbA1c [ 6.77% ± 0.57% vs 7.21% ±0.83%,P<0.05 ],incidence of hypoglycemia( 29% vs 48%,P<0.01 ),and body mass index[ (24.14±2.7 vs 27.63±3.41 ) kg/m2,P<0.01 ] in combined intensive group were statistically improved more than those in the simple intensive group.
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Objective To investigate the incidence and clinical characteristics of mitochondrial tRNA Leu(UUR) gene at nucleotide 3243 A to G mutation in diabetic patients in Dalian District of China. Methods According to ADA(1997)/WHO(1999) diagnostic criteria of diabetes mellitus (DM), 629 patients with DM were screened by polymerase chain reaction and restriction fragment lenghth polymorphism. Genetic and clinical analyses were performed in unrelated patients with the mutation in mtDNA and their family members. Results Six unrelated subjects (probands) with the mutation were detected. Then 6 diabetes patients and 1 IGT from the first degree relatives of these 6 probands were also identified being with the mutation, in which 11 patients are associated with sensory hearing loss and 5 patients requires insulin therapy due to secondary failure to oral hypoglycemic agents. All these patients had lower weight, were younger at diagnosis and most of them were maternally inherited. Conclusion The mutation at nucleotide 3243 in the mitochondrial tRNA Leu(UUR) gene is an important cause of diabetes in Dalian District of China. Compared with the DM patients without the mutation, the clinical characteristics associated with this mutation are young at onset, non obese, maternally inherited and deafness, et al.