1.
Planta Med
; (1): 66-7, 1985 Feb.
Artículo
en Inglés
| MEDLINE
| ID: mdl-3925476
2.
Planta Med
; 51(1): 66-7, 1985 Feb.
Artículo
en Inglés
| MEDLINE
| ID: mdl-17340407
RESUMEN
Brazilin and haematoxylin, plant pigments, were examined for their effects on the Bovine-Lens aldose reductase (LAR)-activity. About 50% inhibition was observed in a concentration of 10 (-4) M-brazilin and 10 (-4) M-haematoxylin, and above 95% inhibition was observed in a concentration of 10 (-3) M-brazilin and 10 (-3)M-haematoxylin. In order to determine the type of inhibition, kinetic studies were also conducted with brazilin and haematoxylin, in which both were found to be noncompetitive inhibitors.