[Detection of antigen-antibody interaction of human adenovirus by the method of surface plasmon resonance].

A possibility to detect adenoviral protein--hexon, using specific antibodies by surface plasmon resonance (SPR) was demonstrated. The hexon of the human adenovirus 2 (Ad2) binds to antibodies immobilized on the sensor surface treated by KNCS and protein A Staphylococcus aureus. The specificity of antihexon antibodies was demonstrated by indirect method of fluorescent antibodies (MFA) and cellular variant of the immunoassay (cELISA).

[Nerve growth factor auto-antibodies in the sera of mothers of schizophrenic children and children from high risk group]. / Autoantitela r faktory rosta vervov v syvorotke krovi materei bol'nykh shizofreniiei detei and detei gruppy vysokogo riska.

A level of autoantibodies (aAB) to nerve growth factor (NGF) was measured in blood serum of children from 4 groups: 1) schizophrenic patients; 2) children from the families, in which one of the parents suffered with schizophrenia (high risk groups of schizophrenia); 3) children with residual-organic damages of CNS; 4) control group. This index was also determined in their mothers. Significant elevation of a titer of aAB to NGF was observed in blood of children from groups 1 and 2 as well as in their mothers, as compared with 3 and 4 groups. Among the mothers of the children from 1 and 2 groups there were met women with different endogenous mental disorders, with the disorders of personality as well as mentally healthy women. An increase of a level of aAB to NGF was found in all the women from groups 1 and 2, independently of their mental status including mentally healthy women. Such results allow to consider elevated level of aAB to NGF as a risk factor of mental pathology.

[A method for improvement of blood circulation in composite grafts in the preventive and reconstructive surgery of burns]. / Metodika uluchsheniia krovoobrashcheniia v slozhnykh transplantatakh v preventivnoi i rekonstruktivnoi khirurgii ozhogov.

In 58 patients after performance of plasty with fatty-cutaneous and fasciocutaneous grafts, the state of circulation in the flaps was studied. The level of ischemic disorders was defined. The medicamentous complexes contributing to improvement of circulation in the grafts are suggested.

[Therapeutic tactics in cold trauma]. / Lechebnaia taktika pri kholodovykh travmakh.

The authors treated 603 sufferers with acute cold damage. The principal reversibility of tissue damage in local cold traumas at the prereactive period is shown. The difference of therapeutical tactics in freezing, primary cryonecrosis, local cold trauma at the prereactive period, frostbite is noted. The necessity of individual immunotherapy of the sufferers is stressed. Criteria for estimation of the effectiveness of aid to such patients are suggested.