Lung cancer screening study from a smoking population in Kunming.

OBJECTIVE: Yunnan, China, is a central tobacco-producing region with a large smoking population and an increasing incidence of lung cancer in recent years. This study aimed to understand the incidence of lung cancer and the characteristics of lung nodules on low-dose computed tomography (LDCT) scans of the chest in a long-term smoking population in Kunming. PATIENTS AND METHODS: Long-term smokers in Kunming who were not at risk of evident lung disease symptoms were recruited through recommendation and publicity by the Kunming University of Science and Technology. RESULTS: Among 375 cases eligible for inclusion,14 cases of lung cancer were detected with a detection rate of 3.73% (95% CI: 2.55%-4.27%), including one case of squamous carcinoma, one case of small cell lung cancer, seven cases of adenocarcinoma of the lung and five cases of early-stage lung cancer (35.71%). In the group of < 6 mm solid nodules and < 5 mm non-solid nodules, no lung cancer was detected in 201 cases; lung cancer was detected in 14 cases in 61 cases, and there was a statistical difference between the two groups (p < 0.05). CONCLUSIONS: The lung cancer detection rate in long-term smokers was high, with the type predominantly adenocarcinoma and a high incidence of lung nodules, and increased when solid nodules≥6 mm or non-solid nodules ≥ 5 mm were present. It is recommended that screening for lung cancer by LDCT of the chest be introduced in the male smoking population who meet the risk factors and that screening for lung cancer in women should be redefined as a high-risk factor.

[Analysis on the data of antibiotic prescriptions comment in China, 2014-2015].

OBJECTIVE: To evaluate the rationality of antibiotic use in the outpatient and emergency departments in some class 3A hospitals in China through International Network for Rational Use of Drugs(INRUD). METHODS: The antibiotic prescriptions were collected from the outpatient and emergency departments in 78 class 3A hospitals of 25 provinces through INRUD during 2014-2015. The basic information of the antibiotic prescriptions and the prescriptions rationality were evaluated. RESULTS: A total of 447 894 prescriptions of antibiotics were analyzed. From 2014 to 2015, the qualified rate the prescriptions increased from 91.52% to 93.08%, and the antibiotic use rate was similar(11.72% and 12.04%). The major irrational prescription type was inappropriate prescription, including inappropriate indication(32.42%, 34.02%)and inappropriate usage and dosage(24.22%, 18.56%). CONCLUSIONS: Totally, the antibiotic use in the outpatient and emergency department reached the standard in China. However, the use of antibiotics didn't meet the national requirements in some area. It is necessary to promote the rational use of antibiotics.