Efecto de los extractos fitoquímicos en la eliminación del barro dentinario en el tratamiento de conductos radiculares / Effects of phytochemical extracts on smear layer removal in root canal treatment

Introduction: Studies suggested that phytochemical products are considered potential solutions to smear layer removal due to their biological safety in cleaning root canal systems, lower toxicity, lower irritant effect and antimicrobial effect. Objective: The aim of the present study was to perform a systematic review to evaluate smear layer removal of root canal systems by different natural product solutions. Methods: systematic review. Search of the literature was performed on Pubmed, Scopus, Cochrane, Web of Science, Scielo and Google Scholar according the PRISMA protocol. Studies were included if they performed the experiments of smear layer removal on extracted permanent human teeth. Articles published in any language without restriction of year of publication were included in this review. The risk of bias assessment in the included studies was evaluated using the Joanna Briggs Institute Critical Appraisal Checklist for Quasi-Experimental Studies. The search strategy resulted in the retrieval of 6221 publications. After the eligibility criteria application, 8 articles were selected for analysis. Results: It was observed that some natural products solutions showed effects on smear layer removal, especially on coronal third. The phytochemical products such as Salvadora persica, chamomile alcohol extract and grape seed extract demonstrated good potential of smear layer removal, however, its effectiveness and clinical applicability are still unclear. Conclusions: Although the limitations of this study, it is possible to highlight those phytochemical products such as Salvadora persica, chamomile alcohol extract and grape seed extract that demonstrated good potential on SL removal(AU)

Introducción: Los productos fitoquímicos se consideran soluciones potenciales para la eliminación del barro dentinario debido a su seguridad biológica en la limpieza del sistema de conductos radiculares, menor toxicidad, menor efecto irritante y efecto antimicrobiano. Objetivo: Evaluar la eliminación del barro dentinario de los sistemas de conductos radiculares mediante diferentes soluciones de productos naturales. Métodos: La búsqueda de la literatura se realizó en Pubmed, Scopus, Cochrane, Web of Science, SciELO y Google Scholar, según el protocolo PRISMA. Los estudios se incluyeron si realizaron los experimentos de eliminación del barro dentinario en dientes humanos permanentes extraídos. En esta revisión se incluyeron artículos publicados en cualquier idioma, sin restricción de año de publicación. La evaluación del riesgo de sesgo en los estudios incluidos se evaluó mediante la lista de verificación de evaluación crítica del Instituto Joanna Briggs para estudios cuasiexperimentales. La estrategia de búsqueda resultó en la recuperación de 6221 publicaciones. Después de la aplicación de los criterios de elegibilidad, se seleccionaron 8 artículos para su análisis. Resultados: Se observó que algunas soluciones de productos naturales mostraron efectos sobre la eliminación del barro dentinario, especialmente en el tercio coronal. Los productos fitoquímicos como salvadora pérsica, extracto de alcohol de manzanilla y extracto de semilla de uva demostraron un buen potencial de eliminación del barro dentinario; sin embargo, su efectividad y aplicabilidad clínica aún no están claras. Conclusiones: A pesar de las limitaciones de este estudio, es posible destacar aquellos productos fitoquímicos como salvadora pérsica, extracto de alcohol de manzanilla y extracto de semilla de uva demostraron buen potencial de eliminación del barro dentinario(AU)

Quiste dentígero en niños / Cisto dentígero na infância / Dentigerous cyst in children

Introducción: El quiste dentígero es el segundo tipo de quistes odontogénicos más frecuentes de los maxilares, desarrollándose a partir de alteraciones del epitelio del órgano del esmalte, donde ocurre una acumulación de líquido entre el epitelio y el esmalte. Por lo general está relacionado a la corona de un diente no erupcionado. Objetivos: el objetivo de este estudio fue analizar los aspectos de diagnóstico y tratamiento de los quistes dentígero en pacientes pediátricos. Métodos: se realizó una búsqueda de artículos científicos indexados en la base de datos bibliográficos PUBMED® en el período comprendido entre febrero y marzo de 2015, mediante el descriptor "dentigerous cyst". Resultados: Se encontraron 147 artículos publicados en los últimos 10 años. Todos los artículos que trataban sobre quiste dentígero en niños fueron incluidos en este estudio. La literatura revisada destaca puntos importantes sobre la epidemiología, manejo y tratamiento de quiste dentígero en pacientes pediátricos. Conclusión: De los artículos revisados se puede concluir que el quiste dentígero es más frecuente en los niños del género masculino y con una edad media de 10 años. Afecta principalmente a la mandíbula y tanto la enucleación como la marsupialización están indicados para el tratamiento de quistes.

Introdução: O cisto dentígero é o segundo tipo de cisto odontogênico mais frequente dos maxilares, desenvolvendo-se a partir de alterações do epitélio reduzido do órgão do esmalte, onde ocorre acúmulo de líquido entre esse epitélio e o esmalte dentário. Normalmente está relacionado à coroa de um dente não irrompido. Objetivos: o propósito deste trabalho foi discutir os aspectos de diagnostico e manejo de cistos dentígeros em pacientes infantis. Métodos: Foi realizada uma busca de artigos científicos indexados na base bibliográfica PUBMED® no período entre fevereiro e março de 2015, com a utilização do descritor "dentigerous cyst". Resultados: foram encontrados 147 artigos publicados nos últimos 10 anos. Todos os trabalhos que que abordavam cisto dentígero em crianças foram incluídos nesse estudo. A literatura revisada, destaca pontos importantes sobre a epidemiologia, manejo e tratamento de cisto dentígero em pacientes infantis. Conclusão: A partir dos artigos revisados pode-se concluir que o cisto dentígero é mais prevalente em crianças do gênero masculino, com idade média de 10 anos. Acomete principalmente a mandíbula e tanto a enucleaçao como a marsupialização são indicados para o tratamento dos cistos.

Introduction: The dentigerous cyst is the second most frequent odontogenic cyst of the jaws, developing from changes in the reduced epithelium of the enamel organ, due to accumulation of fluid between the epithelium and the tooth enamel. Usually it relates to the crown of a non erupted tooth. Objectives: the purpose of this study was to discuss aspects of diagnosis and management of dentigerous cysts in children. Methods: the search of scientific articles indexed in bibliographic database PUBMED® in the period between February and March 2015, using the descriptor "dentigerous cyst" was performed. Results: 147 articles published in the last 10 years were found. All papers that addressed dentigerous cyst in children were included in this study. The articles reviewed highlighted important issues regarding epidemiology, management and treatment of dentigerous cyst in pediatric patients. Conclusion: the dentigerous cyst is more prevalent in males with a mean age of 10 years, mainly affecting the mandible. Both enucleation and marsupialization are indicated for the treatment of cysts.

Immunoexpression of α2-integrin and Hsp47 in hereditary gingival fibromatosis and gingival fibromatosis-associated dental abnormalities.

OBJECTIVE: The purpose of the present study was to investigate the expression of the α2-integrin subunit and heat shock protein 47 (Hsp47) in two families with isolated gingival fibromatosis (GF) form and one family with GF associated with dental abnormalities and normal gingival (NG). STUDY DESIGN: Immunohistochemistry was performed with antibodies against α2-integrin and Hsp47 in specimens from two unrelated families with hereditary gingival fibromatosis (Families 1 and 2) and from one family with a gingival fibromatosis-associated dental abnormality (Family 3); NG samples were used for comparison. The results were analysed statistically. RESULTS: Immunoreactivity for α2-integrin and Hsp47 was observed in the nucleus of epithelial cells of both the basal and suprabasal layer and a more discreet signal was noted in connective tissue in all study samples. Hsp47 showed higher immunoreactivity in Family 2 compared with the other families (p ≤ 0.05). Despite the markup α2-integrin was higher in Family 3 there was no statistically significant difference between the families studied (p ≥ 0.05). CONCLUSIONS: Our results confirmed the heterogeneity of GF, such that similar patterns of expression of the condition may show differences in the expression of proteins such as Hsp47. Although no difference in α2-integrin expression was observed between GF and NG groups, future studies are necessary to determine the exact role of this protein in the various forms of GF and whether it contributes to GF pathogenesis.

Amelogenesis imperfecta and nephrocalcinosis syndrome: a case report and review of the literature.

Amelogenesis imperfecta (AI) is a group of hereditary disorders that affect the quality and/or quantity of dental enamel. This paper describes the clinicopathological features of a patient who was born of consanguineous parents and who presented with oral alterations, including yellow and misshapen teeth, intrapulpal calcifications, delayed tooth eruption, and gum enlargement. Scanning electron microscopy of the teeth revealed hypoplastic enamel, and a renal ultrasound detected bilateral nephrocalcinosis, leading to a diagnosis of AI and nephrocalcinosis syndrome. Since nephrocalcinosis is often asymptomatic and can be associated with impaired renal function, dentists who see children with generalized and thin hypoplastic AI should consider a renal ultrasound scan and referral to a nephrologist, if appropriate. Children with nephrocalcinosis should also be considered for a dental check.