[Simultaneous occurrence of tracheobronchopathia osteochondropastica and mucoepidermoid carcinoma]. / Gleichzeitiges Auftreten von Tracheobronchopathia osteochondroplastica und Mucoepidermoidcarcinom.

In a 51 year old male patient with tracheobronchopathia osteochondroplastica a mucodermoid carcinoma of the middle lobe of the lung was diagnosed. Tracheobronchopathia osteochondroplastica is a rare condition which is occasionally diagnosed by fiberoptic bronchoscopy. More frequently, however, it is only found at autopsy. Mucoepidermoid carcinomas derive from the glands of the bronchial tree and are divided in low-grade and high-grade tumors. The tumor should be locally resected, adjuvant radio- or chemotherapy is ineffective.

[T4/T8 ratio in bronchoalveolar lavage in sarcoidosis--a marker of activity and/or prognosis?]. / T4/T8-Quotient in der bronchoalveolären Lavage (BAL) bei Sarkoidose--Marker von Aktivität und/oder Prognose?

In 158 patients with histologically confirmed intrathoracic sarcoidosis the T4/T8 quotient was checked in broncho-alveolar lavage (BAL) for its informative value with regard to activity and prognosis of the disease. In asymptomatic patients with x-ray type I and normal lung function, in radiological remissions of x-ray types I and improvement in the course of disease in patients whose disease had initially been classified acute, we found statistically significantly higher T4/T8 quotients than in the other patient groups; we did not observe any deterioration in the course of the disease. High T4/T8 quotients will thus not generally point to an active or progressing disease; the information conveyed by these data is of limited clinical usefulness in individual cases only.

[Tracheobronchopathia osteochondroplastica and coexistent mucoepidermoid carcinoma of the lung: Case report]. / Tracheobronchopathia osteochondroplastica und koexistentes Mukoepidermoidkarzinom der Lunge: Fallvorstellung.

Pneumonia of the middle lobe that had been diagnosed by x-ray in a male patient of 51 years of age did not recede completely despite antibiotic treatment. CT showed a space-occupying growth in the middle lobe of about 1.5 cm size, with consecutive atelectasis. Bronchoscopy revealed a pronounced pattern of tracheobronchopathia osteochondroplastica, but it was not possible to confirm the middle lobe syndrome (Brock's syndrome) by histological examination. A mucoepidermoid carcinoma of the middle lobe was histologically established by thoracotomy besides the tracheobronchopathia osteochondroplastica. 9 months post-operatively there is no pointer to any recurrence or metastasising.

[Bronchoalveolar lavage in fibrosing alveolitis--a parameter for evaluating activity and prognosis?]. / Bronchoalveoläre Lavage (BAL) bei fibrosierender Alveolitis--Parameter zur Beurteilung von Aktivität und Prognose?

Bronchoalveolar lavages (BAL) were performed in 19 patients in whom fibrotising alveolitis had been detected and confirmed. The patients were then followed up and controlled clinically for more than 12 months. The courses of the diseases did not reveal any group-specific behaviour (taking lymphocytic and granulocytic lavages into consideration) and were not predictable on the basis of the lavage patterns. With a BAL lymphocytosis, 40% of the patients showed clinical improvement and in 30% the disease became stable whereas in another 30% there was a deterioration. If more than 10% BAL granulocytes were present, 50% of the patients showed clinical deterioration, whereas the course became stable in 37.5% and clinical improvements were recorded in 12.5% of the patients.

[Tuberous sclerosis with pulmonary involvement. Case report]. / Tuberöse Sklerose mit Lungenbeteiligung. Kasuistik.

The presented patient suffered of seizures during childhood and exhibited the typical skin lesions of tuberous sclerosis. However, the diagnosis was not made until the patient was 26 years old. He had involvement of the central nervous system, the skin, the kidneys, and the lungs. After he developed renal failure he underwent hemodialysis for 57 months and suffered an intracerebral hemorrhage followed by cardiorespiratory arrest age 36.

[Value of bronchoalveolar lavage and findings of cytologic studies in the diagnosis of interstitial lung diseases]. / Der Stellenwert der bronchoalveolären Lavage und zytologischer Untersuchungsbefunde in der Diagnostik interstitieller Lungenerkrankungen.

In 27 patients with roentgenologically suspected interstitial pulmonary disease, bronchoscopy was carried out with the rigid bronchoscope. The examination material obtained (BAL fluid, transbronchial lung biopsy, perbronchial lymph node biopsy, mucosal biopsy) was submitted to a histological and cytological work-up. The established cell distribution in the BAL fluid confirmed the findings reported in the literature. In sarcoidosis, irrespective of the roentgenological stage, a 30 to 35% lymphocytosis was observed. The combination of BAL, perbronchial lymph node biopsy, transbronchial lung biopsy and bronchial mucosal biopsy permitted confirmation of the sarcoidosis in more than 90% of the cases. The -hit rate- of the perbronchial lymph node biopsy was 90.6% in stage 1, 85% in stage 2, and 77% in stage 3.