A produção sobre Ciência Aberta na área de Ciência da Informação no Brasil: análise no mapa temático das publicações da Brapci ­ 2015 a 2019 / The production on Open Science in the Information Science area in Brazil: analysis on the thematic map of Brapci publications ­ 2015 to 2019 / La producción sobre Ciencia Abierta en el área de Ciencias de la Información en Brasil: análisis sobre el mapa temático de las publicaciones de Brapci ­ 2015 a 2019

O texto discorre sobre relações entre a Ciência da Informação e o movimento da Ciência Aberta, sob a ótica de artigos científicos identificados na Base de Dados Referenciais de Artigos de Periódicos em Ciência da Informação. Objetiva determinar dimensões, campos e movimentos que se relacionam, estabelecendo um panorama dessa relação com as pesquisas brasileiras no período entre 2015 e 2019 no domínio da comunicação científica. A metodologia é a revisão narrativa de literatura, por meio da aplicação da análise de títulos, resumos e palavras-chave dos artigos selecionados. O campo empírico é composto pelos resultados obtidos pela busca na base, totalizando 36 resultados. Conclui-se que a Ciência da Informação está se relacionando com a Ciência Aberta, observando-se a prevalência de estudos sobre temáticas de dados de pesquisa abertos e sobre repositórios, de acordo com o período observado, como maneiras de aperfeiçoar os fazeres científicos.

The text discusses the relationship between Information Science and the Open Science movement, from the perspective of scientific articles identified in the Referential Database of Journal Articles in Information Science. The objective is to determine the dimensions, fields, and movements related, establishing an overview of this relationship with Brazilian research between 2015 and 2019, in the domain of scientific communication. The methodology employed is the narrative literature review, through the analysis of titles, abstracts, and keywords of selected articles. The empirical field consists of the results obtained through the search in the database, totaling 36 results. It is concluded that Information Science is relating to Open Science, with a prevalence of studies on open research data and repositories, according to the observed period, as ways to enhance scientific practices.

El texto discute la relación entre la Ciencia de la Información y el movimiento de la Ciencia Abierta, desde la perspectiva de artículos científicos identificados en la Base de Datos Referencial de Artículos de Revistas en Ciencia de la Información. El objetivo es determinar dimensiones, campos y movimientos relacionados, estableciendo una visión general de esta relación con la investigación brasileña entre 2015 y 2019, en el ámbito de la comunicación científica. La metodología es la revisión narrativa de literatura, a través del análisis de títulos, resúmenes y palabras clave de artículos seleccionados. El campo empírico consiste en los resultados obtenidos mediante la búsqueda en la base de datos, con 36 resultados. Se concluye que la Ciencia de la Información se relaciona con la Ciencia Abierta, con una prevalencia de estudios sobre datos de investigación abiertos y repositorios, según el período observado, como formas de mejorar las prácticas científicas.

Lessons Learned Establishing the Palliative Care Research Cooperative's Qualitative Data Repository.

Data sharing is increasingly an expectation in health research as part of a general move toward more open sciences. In the United States, in particular, the implementation of the 2023 National Institutes of Health Data Management and Sharing Policy has made it clear that qualitative studies are not exempt from this data sharing requirement. Recognizing this trend, the Palliative Care Research Cooperative Group (PCRC) realized the value of creating a de-identified qualitative data repository to complement its existing de-identified quantitative data repository. The PCRC Data Informatics and Statistics Core leadership partnered with the Qualitative Data Repository (QDR) to establish the first serious illness and palliative care qualitative data repository in the U.S. We describe the processes used to develop this repository, called the PCRC-QDR, as well as our outreach and education among the palliative care researcher community, which led to the first ten projects to share the data in the new repository. Specifically, we discuss how we co-designed the PCRC-QDR and created tailored guidelines for depositing and sharing qualitative data depending on the original research context, establishing uniform expectations for key components of relevant documentation, and the use of suitable access controls for sensitive data. We also describe how PCRC was able to leverage its existing community to recruit and guide early depositors and outline lessons learned in evaluating the experience. This work advances the establishment of best practices in qualitative data sharing.

State of open science in cancer research.

PURPOSE: This study has been focused on assessing the Open Science scenario of cancer research during the period 2011-2021, in terms of the derived scientific publications and raw data dissemination. METHODS: A cancer search equation was executed in the Science Citation Index-Expanded, collecting the papers signed by at least one Spanish institution. The same search strategy was performed in the Data Citation Index to describe dataset diffusion. RESULTS: 50,822 papers were recovered, 71% of which belong to first and second quartile journals. 59% of the articles were published in Open Access (OA) journals. The Open Access model and international collaboration positively conditioned the number of citations received. Among the most productive journals stood out Plos One, Cancers, and Clinical and Translational Oncology. 2693 genomics, proteomics and metabolomics datasets were retrieved, being Gene Expression Omnibus the favoured repository. CONCLUSIONS: There has been an increase in oncology publications in Open Access. Most were published in first quartile journals and received higher citations than non-Open Access articles, as well as when oncological investigation was performed between international research teams, being relevant in the context of Open Science. Genetic repositories have been the preferred for sharing oncology datasets. Further investigation of research and data sharing in oncology is needed, supported by stronger Open Science policies, to achieve better data sharing practices among three scientific main pillars: researchers, publishers, and scientific organizations.

A library of electrophysiological responses in plants - a model of transversal education and open science.

Electrophysiology in plants is understudied, and, moreover, an ideal model for student inclusion at all levels of education. Here, we report on an investigation in open science, whereby scientists worked with high school students, faculty, and undergraduates from Chile, Germany, Serbia, South Korea, and the USA. The students recorded the electrophysiological signals of >15 plant species in response to a flame or tactile stimulus applied to the leaves. We observed that approximately 60% of the plants studied showed an electrophysiological response, with a delay of ~ 3-6 s after stimulus presentation. In preliminary conduction velocity experiments, we verified that observed signals are indeed biological in origin, with information transmission speeds of ~ 2-9 mm/s. Such easily replicable experiments can serve to include more investigators and students in contributing to our understanding of plant electrophysiology.

Bibliotecários e os desafios da Ciência Aberta: habilidades, recursos e serviços / Librarians and the challenges of Open Science: skills, resources and services / Bibliotecarios y los desafíos de la Ciencia Abierta: habilidades, recursos y servicios

Este estudo tem como objetivo identificar, na literatura científica, produtos e serviços desenvolvidos por bibliotecários vislumbrando as práticas de Ciência Aberta. A questão principal é identificar: qual o papel dos bibliotecários frente aos desafios da Ciência Aberta? Predominantemente qualitativa, esta pesquisa pode ser caracterizada como bibliográfica, exploratória e descritiva. Para atingir seu objetivo, utilizou-se a técnica de revisão rápida de literatura. Foi realizado um levantamento de publicações indexadas na Brapci, na Scopus e na Web of Science, sendo recuperadas três publicações em cada. Ao excluir um título que se repetiu, o corpus da pesquisa configurou-se com seis artigos e dois resumos apresentados em evento. Conclui-se que debates sobre o novo modus operandi de fazer ciência vêm aumentando e os bibliotecários parecem intimamente relacionados às ações de Ciência Aberta nas diversas etapas da pesquisa científica. Devido às suas habilidades e aos seus serviços, entende-se que exercem um dos papéis centrais na concretização da abertura da ciência.

This study aims to identify, in the scientific literature, products and services developed by librarians with a view to Open Science practices. The main question is to identify: what role is played by librarians facing the challenges of Open Science? Predominantly qualitative, this research can be characterized as bibliographic, exploratory, and descriptive. To achieve its objective, a rapid literature review technique was used. A survey of publications indexed in Brapci, Scopus and Web of Science was carried out, and three publications from each were retrieved. After excluding one title that was repeated, the research corpus consisted of six articles and two abstracts presented at an event. We conclude that debates about the new modus operandi of doing science have been increasing and librarians seem closely related to Open Science actions in the various stages of scientific research. Because of their skills and services, they play one of the central roles to achieve the opening of science.

Este studio tiene como objetivo identificaren la literature científica los productos y servicios desarrollados por los bibliotecarios com vistas a las prácticas de la Ciencia Abierta. La cuestión principal es identificar: ¿ cuál es el papel de los bibliotecarios ante los desafíos de la Ciencia Abierta? Predominantemente cualita-tiva, esta investigación puede caracterizar se como bibliográfica, exploratoria y descriptiva. Para lograr su objetivo, se utilizó la técnica de revision rápida de la literatura. Se realizó un estudio de las publicaciones indexadas en Brapci, Scopus y Web of Science, recuperándo se tres publicaciones en cada una de ellas. Al excluir un título repetido, el corpus de la investigación quedó configurado con seis artículos y dos resúmenes presentados en un evento. Concluimos que los debates sobre el nuevo modus operandi de hacer ciencia han aumentado y los bibliotecarios parecen estar estrechamente relacionados con las acciones de la Ciencia Abierta en las distintas etapas de la investigación científica. Por sus habilidades y servicios, se entiende que ejercen uno de los papeles centrales en la realización de la Ciencia Abierta.

Endorsement of open science practices by dental journals: A meta-research study.

OBJECTIVES: This study evaluates the endorsement of open science practices by dental journals. MATERIALS AND METHODS: This was a meta-research study that included journals listed in the 2021 Journal Citation Reports under Dentistry. A comprehensive evaluation was performed by accessing journal websites to ascertain the availability of publicly accessible instructions to authors in Portuguese, English, or Spanish. A researcher extracted information from the "Instructions for Authors" section, encompassing the journal's impact factor, mention of any reporting guidelines, details on data sharing, acceptance of articles in preprint format, and information regarding study protocol registration. Descriptive data analysis was conducted using the Stata 14.0 program, and an Open Science Score (OSS) (ranging from 0 to 100 %) was calculated for each journal by considering five open science practices. Pearson's correlation test was conducted to determine the relationship between the OSS score and journal impact factor. RESULTS: Ninety journals were included in the study. Most journals (70 %) indicated the mandatory use of reporting guidelines, while 60 % recommended data sharing. Conversely, 46.7 % did not provide information on study protocol registration, and 44.4 % stipulated them as mandatory for authors. Regarding preprints, 50 % of the journals did not provide any information, but 46.7 % confirmed their acceptance. The mean OSS was 52.9 % (standard deviation 26.2). There was a weak correlation (Pearson's correlation coefficient of 0.221) between the journal impact factor and OSS (P-value=0.036). CONCLUSION: This study found varying degrees of endorsement of open science practices among dental journals. CLINICAL SIGNIFICANCE: Dental practitioners rely on high-quality, evidence-based research for informed decision-making. By assessing the endorsement of open science practices, our study contributes to improving the quality and reliability of dental research, ultimately enhancing the evidence base for clinical practice.

50 anos da RBSO, 25 anos do SciELO e 38 anos da ABEC Brasil: contribuições para a ciência aberta / 50 years of RBSO, 25 years of SciELO, and 38 years of ABEC Brasil: contributions to open science

Resumo Para comemorar o cinquentenário da Revista Brasileira de Saúde Ocupacional (RBSO), foi realizado, em fevereiro de 2024, o evento "50 anos da RBSO, 25 anos do SciELO e 38 anos da ABEC Brasil: contribuições para a ciência aberta". Esta nota editorial reporta tal evento, descrevendo brevemente o histórico da revista e das entidades representadas: o projeto Scientific Electronic Library Online (SciELO) e a Associação Brasileira de Editores Científicos (Abec Brasil), assim como seus alcances, seus desafios e suas perspectivas. A ciência aberta foi escolhida como assunto para estimular o debate, por ser um tema relevante e transversal que perpassa as atividades da revista e das entidades. A RBSO segue os princípios do acesso aberto desde sua criação, ainda antes do surgimento do movimento do acesso aberto e do debate em torno da ciência aberta. Mais recentemente, aderiu a outras práticas da ciência aberta, como a aceitação de preprints, o incentivo ao depósito de dados de pesquisa e a adoção de políticas editoriais alinhadas. SciELO e Abec Brasil têm sido importantes catalisadores das iniciativas relacionadas à ciência aberta, visando fortalecer os periódicos e ampliar as colaborações científicas e o compartilhamento do conhecimento científico em benefício da ciência e da sociedade.

Abstract As part of the celebration activities for the fiftieth anniversary of the Brazilian Journal of Occupational Health (RBSO), the event "50 years of RBSO, 25 years of SciELO, and 38 years of ABEC Brasil: contributions to open science" was held in February 2024. This editorial note reports on that event, briefly describing the history of the journal and the entities represented: the Scientific Electronic Library Online (SciELO) project and the Brazilian Association of Scientific Editors (ABEC Brasil), as well as their scopes, challenges, and prospects. Open Science was chosen as the theme to stimulate debate, as it is a relevant and cross-cutting issue that permeates the activities of the journal and the organizations. RBSO has followed the open access principles since its inception, even before the emergence of the open access movement and the debate around open science. More recently, it has adopted other open science practices such as accepting preprints, encouraging research data deposition, and adopting aligned editorial policies. SciELO and ABEC Brasil have been important catalysts for initiatives related to open science, aiming not only to strengthen journals but also to expand scientific collaborations and the sharing of scientific knowledge for the benefit of science and society.

Retos y cambios en revistas de acceso abierto / Challenges and changes in open access journals / Desafios e mudanças nas revistas de acesso aberto

Resumen Se reflexiona sobre la reciente evaluación de Clarivate a las revistas que tiene indexadas en Web of Science, a la luz de la importancia de proteger la integridad de la comunicación científica. Se mencionan algunos cambios y novedades de la revista Pensar en Movimiento, efectivos en el 2023.

Abstract This editorial discusses the recent Clarivate evaluation of hundreds of journals indexed in Web of Science, in light of the importance of protecting the integrity of scientific communication. A few changes and news for 2023 regarding Pensar en Movimiento are also mentioned.

Resumo Este editorial reflete sobre a recente avaliação que a Clarivate fez das revistas que indexou no Web of Science, tendo em vista a importância de proteger a integridade da comunicação científica. Algumas mudanças e novidades da revista Pensar en Movimiento, a partir de 2023, são mencionadas.

Art driven by visual representations of chemical space.

Science and art have been connected for centuries. With the development of new computational methods, new scientific disciplines have emerged, such as computational chemistry, and related fields, such as cheminformatics. Chemoinformatics is grounded on the chemical space concept: a multi-descriptor space in which chemical structures are described. In several practical applications, visual representations of the chemical space of compound datasets are low-dimensional plots helpful in identifying patterns. However, the authors propose that the plots can also be used as artistic expressions. This manuscript introduces an approach to merging art with chemoinformatics through visual and artistic representations of chemical space. As case studies, we portray the chemical space of food chemicals and other compounds to generate visually appealing graphs with twofold benefits: sharing chemical knowledge and developing pieces of art driven by chemoinformatics. The art driven by chemical space visualization will help increase the application of chemistry and art and contribute to general education and dissemination of chemoinformatics and chemistry through artistic expressions. All the code and data sets to reproduce the visual representation of the chemical space presented in the manuscript are freely available at https://github.com/DIFACQUIM/Art-Driven-by-Visual-Representations-of-Chemical-Space- . Scientific contribution: Chemical space as a concept to create digital art and as a tool to train and introduce students to cheminformatics.

La publicación de los conjuntos de datos por medio de las revistas científicas: el caso de pensar en movimiento / A publicação de conjuntos de dados através de revistas científicas: o caso de Pensar en Movimiento / The publication of data sets through scientific journals: The case of Pensar en Movimiento

Varela-Briceño, M. (2023). La publicación de los conjuntos de datos por medio de las revistas científicas: el caso de Pensar en Movimiento. PENSAR EN MOVIMIENTO: Revista de Ciencias del Ejercicio y la Salud, 21(1), 1-6. La publicación científica ha evolucionado y con ellos las revistas académicas, desde sus inicios en versiones impresas y actualmente las electrónicas, lo cual ha llevado a una serie de cambios en los procesos de gestión. Es así que se han establecidos los movimientos del acceso y la ciencia abierta. El propósito de este editorial es hacer un recorrido sobre la publicación de conjuntos de datos, su importancia y ventajas; además de mostrar la iniciativa de Pensar en Movimiento de poner a disposición las bases de datos que acompañan los artículos de investigación.

Varela-Briceño, M. (2023). The publication of data sets through scientific journals: The case of Pensar en Movimiento. PENSAR EN MOVIMIENTO: Revista de Ciencias del Ejercicio y la Salud, 21(1), 1-6. Scientific publishing has evolved, and academic journals have evolved with it—initially in printed versions, and currently in electronic ones. This has resulted in a series of changes in management processes. For instance, the movements for open access and science have emerged. The purpose of this editorial is to present an overview of the publication of data sets, its importance and advantages, in addition to showing the initiative of Pensar en Movimiento to make available the data bases that go along with research articles.

Varela-Briceño, M. (2023). A publicação de conjuntos de dados através de revistas científicas: o caso de Pensar en Movimiento. PENSAR EN MOVIMIENTO: Revista de Ciencias del Ejercicio y de la Salud, 21(1), 1-6. A publicação científica evoluiu, e com ela as revistas acadêmicas; desde sua criação, em versões impressas, e atualmente eletrônicas, o que levou a uma série de mudanças nos processos de gestão. É assim que os movimentos de acesso e ciência aberta foram estabelecidos. O objetivo deste editorial é fazer uma jornada pela publicação de conjuntos de dados, sua importância e vantagens; além de mostrar a iniciativa da revista Pensar en Movimiento de disponibilizar as bases de dados que acompanham os artigos de pesquisa.

Architecture of a Data Portal for Publishing and Delivering Open Data for Atmospheric Measurement.

Atmospheric data are collected by researchers every day. Campaigns such as GOAmazon 2014/2015 and the Amazon Tall Tower Observatory collect essential data on aerosols, gases, cloud properties, and meteorological parameters in the Brazilian Amazon basin. These data products provide insights and essential information for analyzing and predicting natural processes. However, in Brazil, it is estimated that more than 80% of the scientific data collected are not published due to the lack of web portals that collect and store these data. This makes it difficult, or even impossible, to access and integrate the data, which can result in the loss of significant amounts of information and significantly affect the understanding of the overall data. To address this problem, we propose a data portal architecture and open data deployment that enable Big Data processing, human interaction, and download-oriented approaches with tools that help users catalog, publish and visualize atmospheric data. Thus, we describe the architecture developed, based on the experience of the Atmospheric Radiation Measurement Data Center, which incorporates the principles of FAIR, the infrastructure and content management system for managing scientific data. The portal partial results were tested with environmental data from contaminated areas at the University of São Paulo. Overall, this data portal creates more shared knowledge about atmospheric processes by providing users with access to open environmental data.

Current landscape and future directions of synthetic biology in South America.

Synthetic biology (SynBio) is a rapidly advancing multidisciplinary field in which South American countries such as Chile, Argentina, and Brazil have made notable contributions and have established leadership positions in the region. In recent years, efforts have strengthened SynBio in the rest of the countries, and although progress is significant, growth has not matched that of the aforementioned countries. Initiatives such as iGEM and TECNOx have introduced students and researchers from various countries to the foundations of SynBio. Several factors have hindered progress in the field, including scarce funding from both public and private sources for synthetic biology projects, an underdeveloped biotech industry, and a lack of policies to promote bio-innovation. However, open science initiatives such as the DIY movement and OSHW have helped to alleviate some of these challenges. Similarly, the abundance of natural resources and biodiversity make South America an attractive location to invest in and develop SynBio projects.

De la tecnocracia a la equidad y la sustentabilidad: por otra ciencia abierta / Da tecnocracia à equidade e à sustentabilidade: por uma outra ciência aberta / From technocracy to equity and sustainability: for another open science

Fue por medio de los estudios sobre softwares de periódicos científicos que Juan Pablo Alperin comenzó a desarrollar investigaciones sobre la comunicación científica, principalmente en relación a la temática de acceso abierto y su cuestión más amplia que envuelve la ciencia abierta. En entrevista con la Reciis, el profesor e investigador argumenta que es preciso pensar en cómo abrir el acceso al conocimiento y no apenas garantirlo. En ese sentido, la reflexión sobre cómo hacer ciencia abierta promueve discusiones para tornar el sistema de investigación científica con más equidad y más colaborativo. El profesor comenta sobre los efectos positivos y los desafíos que la pandemia de covid-19 promueve en relación a la comunicación científica. Alperin destaca iniciativas en la América Latina volcadas a una ciencia más democrática y reafirma la necesidad de defender una ciencia abierta que interrogue su modo de actuar, siendo con eso, menos tecnocrática. Juan Pablo Alperin es profesor asociado de la Simon Fraser University

Foi por meio dos estudos sobre softwares de periódicos científicos que Juan Pablo Alperin passou a desenvolver pesquisas sobre a comunicação científica, principalmente em relação à temática de acesso aberto e sua questão mais ampla que envolve a ciência aberta. Em entrevista à Reciis, o professor e pesquisador argumenta que é preciso pensar em como se abrir o acesso ao conhecimento e não apenas garanti-lo. Nesse sentido, a reflexão sobre como fazer ciência aberta promove discussões para tornar o sistema de pesquisa científica mais equânime e colaborativo. O professor comenta sobre os efeitos positivos e os desafios que a pandemia de covid-19 promoveu em relação à comunicação científica. Alperin destaca iniciativas na América Latina voltadas a uma ciência mais democrática e reafirma a necessidade de se defender uma ciência aberta que interrogue o seu modo de agir, sendo, com isso, menos tecnocrática. Juan Pablo Alperin é professor associado da Simon Fraser University.

Through studies on software for scientific journals, Juan Pablo Alperin began to develop research on scientific communication, mainly on the theme of open access and its broader issue that involves open science. in an interview with Reciis, the professor and researcher argues that it is necessary to think about how to open access to knowledge and not just guarantee it. In this sense, reflection on how to do open science promotes discussions to make the scientific research system more equitable and collaborative. The professor states the positive effects and challenges that the covid-19 pandemic has brought about for scientific communication. Alperin highlights initiatives in Latin America aimed at a more democratic science and reaffirms the need to defend an Open Science that questions its way of acting, being less technocratic. Juan Pablo Alperin is an associate professor at Simon Fraser University.

Progress and Impact of Latin American Natural Product Databases.

Natural products (NPs) are a rich source of structurally novel molecules, and the chemical space they encompass is far from being fully explored. Over history, NPs have represented a significant source of bioactive molecules and have served as a source of inspiration for developing many drugs on the market. On the other hand, computer-aided drug design (CADD) has contributed to drug discovery research, mitigating costs and time. In this sense, compound databases represent a fundamental element of CADD. This work reviews the progress toward developing compound databases of natural origin, and it surveys computational methods, emphasizing chemoinformatic approaches to profile natural product databases. Furthermore, it reviews the present state of the art in developing Latin American NP databases and their practical applications to the drug discovery area.

Revisión escéptica del estado de la neuroimagen en el trastorno por déficit de atención e hiperactividad / Skeptical review of the state of neuroimaging in attention deficit hyperactivity disorder

Resumen El trastorno por déficit de atención e hiperactividad (TDAH) ha sido estudiado por medio de resonancia magnética durante más de 30 años, superando 2200 artículos en PubMed. Sin embargo, todavía no se entienden bien las bases cerebrales del TDAH. Esto refleja la dificultad de replicar resultados, que afecta a casi todos los esfuerzos científicos. Los factores que contribuyen a resultados falsos positivos incluyen tamaños de muestra pequeños y la superabundancia de métodos analíticos. En el campo de la genética mole cular, estos retos conllevaron a la adopción del requisito de compartir los datos genéticos inmediatamente para que la comunidad pueda trabajar de forma conjunta, y que se apliquen métodos rigurosos tomando en cuenta la verdadera cantidad de pruebas estadísticas. Esto ha producido resultados más creíbles, aunque con tamaños de efecto muy reducidos respecto a los anteriores. En este breve resumen se usan dos consorcios, uno internacional llamado ENIGMA (Enhancing Neuro-Imaging Genetics through Meta-Analysis), y el otro norteamericano llamado ABCD (Adolescent and Cognitive Behavior Development Study), para ilustrar este movimiento a la ciencia abier ta. Aquí se revisa la primera cosecha de hallazgos, aunque todavía limitados a análisis transversales. Ya que ABCD fue diseñado como esfuerzo longitudinal, la combinación con la maduración continua del campo promete transformar nuestro entendimiento de la patofisiología de TDAH (probablemente también alterando la definición diagnostica al largo plazo) para acercarnos al día en el cual la neuroimagen sea útil en la clínica.

Abstract Attention-deficit/hyperactivity disorder (ADHD) has been the focus of magnetic resonance imaging studies for more than 30 years, with more than 2200 articles listed in PubMed. Nevertheless, the brain substrates of ADHD remain poorly understood. This reflects the crisis of replicability across nearly all scientific endeavors, deriving from factors such as small sample sizes combined with a proliferation in analytical approaches, yielding high rates of false positive results. The field of molecular genetics confronted this by adopting open and immedi ate sharing of raw data and insistence on rigorous corrections for multiple comparisons. These strategies are yielding more robust genetic findings, albeit with much smaller effect sizes than before. This brief review focuses on two recent consortium efforts, i.e., the international Enhancing Neuro-Imaging Genetics through Meta-Analysis (ENIGMA), and the U.S. Adolescent Behavior & Cognitive Developm ent Study (ABCD). Both embrace the culture of open science, and are beginning to yield credible findings, despite being limited initially to cross-sectional analyses. As the field continues to mature, these and other ongoing longitudinal large-scale studies are poised to transform our understanding of the pathophysiology of ADHD to bring closer the day when neuroimaging can contribute to clinical utility.

E se o scanCOVID-19 tivesse nascido em 2022? / And if the scanCOVID-19 had been born in 2002? / Y si el scanCOVID-19 hubiese nacido en 2022?

Acompanhar a velocidade das mudanças, qualitativas e quantitativas, na produção de conhecimento em tempos de pandemia de covid-19 impulsionou o desenvolvimento de inúmeras iniciativas de monitoramento da informação científica. O scanCOVID-19 foi uma delas. Essa nota de conjuntura procura situar a importância do investimento em projetos dessa natureza, que possam ter reflexos nas relações entre ciência, Estado e sociedade.

Keeping up with the speed of qualitative and quantitative changes in the production of knowledge in times of the covid-19 pandemic was a stimulus to the development of numerous initiatives to track scientific information. The scanCOVID-19 was one of them. This note seeks to situate the importance of investing in projects of the same nature, which may have effects on the relations between science, state, and society.

Acompañar la velocidad de los cambios, cualitativos y cuantitativos, en la producción de conocimiento en tiempos de la pandemia de covid-19 ha impulsado el desarrollo de numerosas iniciativas de seguimiento de la información científica. El scanCOVID-19 fue uno de ellos. Esta nota de coyuntura busca situar la importancia de invertir en proyectos de esta naturaleza, que puedan tener efectos sobre las relaciones entre ciencia, Estado y sociedad.

[Skeptical review of the state of neuroimaging in attention deficit hyperactivity disorder]. / Revisión escéptica del estado de la neuroimagen en el trastorno por déficit de atención e hiperactividad.

Attention-deficit/hyperactivity disorder (ADHD) has been the focus of magnetic resonance imaging studies for more than 30 years, with more than 2200 articles listed in PubMed. Nevertheless, the brain substrates of ADHD remain poorly understood. This reflects the crisis of replicability across nearly all scientific endeavors, deriving from factors such as small sample sizes combined with a proliferation in analytical approaches, yielding high rates of false positive results. The field of molecular genetics confronted this by adopting open and immediate sharing of raw data and insistence on rigorous corrections for multiple comparisons. These strategies are yielding more robust genetic findings, albeit with much smaller effect sizes than before. This brief review focuses on two recent consortium efforts, i.e., the international Enhancing Neuro-Imaging Genetics through Meta-Analysis (ENIGMA), and the U.S. Adolescent Behavior & Cognitive Developm ent Study (ABCD). Both embrace the culture of open science, and are beginning to yield credible findings, despite being limited initially to cross-sectional analyses. As the field continues to mature, these and other ongoing longitudinal large-scale studies are poised to transform our understanding of the pathophysiology of ADHD to bring closer the day when neuroimaging can contribute to clinical utility.

El trastorno por déficit de atención e hiperactividad (TDAH) ha sido estudiado por medio de resonancia magnética durante más de 30 años, superando 2200 artículos en PubMed. Sin embargo, todavía no se entienden bien las bases cerebrales del TDAH. Esto refleja la dificultad de replicar resultados, que afecta a casi todos los esfuerzos científicos. Los factores que contribuyen a resultados falsos positivos incluyen tamaños de muestra pequeños y la superabundancia de métodos analíticos. En el campo de la genética molecular, estos retos conllevaron a la adopción del requisito de compartir los datos genéticos inmediatamente para que la comunidad pueda trabajar de forma conjunta, y que se apliquen métodos rigurosos tomando en cuenta la verdadera cantidad de pruebas estadísticas. Esto ha producido resultados más creíbles, aunque con tamaños de efecto muy reducidos respecto a los anteriores. En este breve resumen se usan dos consorcios, uno internacional llamado ENIGMA (Enhancing Neuro-Imaging Genetics through Meta-Analysis), y el otro norteamericano llamado ABCD (Adolescent and Cognitive Behavior Development Study), para ilustrar este movimiento a la ciencia abierta. Aquí se revisa la primera cosecha de hallazgos, aunque todavía limitados a análisis transversales. Ya que ABCD fue diseñado como esfuerzo longitudinal, la combinación con la maduración continua del campo promete transformar nuestro entendimiento de la patofisiología de TDAH (probablemente también alterando la definición diagnostica al largo plazo) para acercarnos al día en el cual la neuroimagen sea útil en la clínica.