Analysis of factors associated with erectile dysfunction after renal transplantation / 现代泌尿外科杂志

【Objective】 To explore the factors influencing erectile dysfunction (ED) in male patients after renal transplantation, so as to provide basis for the prevention and treatment of this disease. 【Methods】 Kidney transplant recipients followed up in the Kidney Transplant Clinic of Xijing Hospital during Sep.1, 2022 and May 1, 2023 were selected as the study objects.Questionnaires were distributed, and the erectile function was measured with Sexual Health Inventory for Men (SHIM).Factors associated with ED were analyzed with multivariate logistic regression. 【Results】 A total of 300 questionnaires were distributed, and 276 valid ones were collected, including 182 cases (65.9%) suffering from ED of varying degrees.Multivariate logistic regression analysis showed that age [(50 years, OR: 0.120, 95%CI: 0.033-0.405, P50 years, OR: 0.223, 95%CI: 0.102-0.463, P40-50 years/>50 years, OR: 0.320, 95%CI: 0.139-0.719, P<0.01)], level of International Prostate Symptom Score (IPSS) (OR: 1.95, 95%CI: 1.211-3.248, P<0.01), International Prostate Symptom Score-Quality of Life item (IPSS-QoL) (OR: 1.482, 95%CI: 1.201-1.854, P<0.01), and income [(≥10 000 Yuan/<3 000 Yuan, OR: 0.156, 95%CI: 0.053-0.429, P<0.001), (5 000-<10 000 Yuan/<3 000 Yuan, OR: 0.418, 95%CI: 0.199-0.864, P<0.05), (≥10 000 Yuan/3 000-<5 000 Yuan, OR: 0.205, 95%CI: 0.069-0.573, P<0.01)] were independent and significant factors of ED. 【Conclusion】 The prevalence of ED in renal transplantation recipients is high.Age, income, IPSS and IPSS-QoL are the influencing factors.ED after renal transplantation is not only determined by physical and functional factors, but also closely related to social and psychological factors.

Are pediatricians familiar with hereditary angioedema?

Background: Hereditary angioedema (HAE) is an autosomal dominant disease characterized by recurrent episodes of subcutaneous or mucosal edema caused by excess bradykinin. The aim of the present study was to assess the knowledge of pediatricians about hereditary angioedema. Methods: An online survey with 12 HAE-related and 14 demographics-related questions was e-mailed to all pediatricians who were members of the Brazilian Society of Pediatrics (n = 17 145) once a week during the months of June and July 2021. The electronic questionnaire assessed clinical manifestations, diagnosis, and treatment of hereditary angioedema in children and adolescents. Results: Four hundred and fifty-five pediatricians responded to the questionnaire (2.6%), of whom 55 (12.1%) were board certified in Allergy and Immunology (A/I), while 400 (87.9%) were not (N-A/I). Three hundred and sixty-eight (80.9%) were female, 289 (55.7%) were under 50 years of age, 286 (62.9%) graduated from Medical School more than 10 years previously, 83 (18.2%) held an MSc/PhD degree, and 253 (55.6%) were living in the Southeast Region of Brazil. The median number of correct answers to the questions related to HAE among A/I was 7 out of 12 (58.3%), with median ranging from 4.5 to 8 correct answers, while for N-A/I it was 3 (25%), with median ranging from 2.5 to 4 correct answers (p < 0.001). Conclusion: Knowledge about HAE among Brazilian pediatricians, whether board certified in Allergy and Immunology or not, was unsatisfactory. HAE is a rare disease, largely unknown among physicians; therefore, increasing awareness may lead to improvement in diagnosis and treatment.

The effect of age on health-related quality of life for head and neck cancer patients up to 1 year after curative treatment.

OBJECTIVES: The aim was to evaluate the effect of age on health-related quality of life (HRQOL) for patients with head and neck cancer (HNC), treated with curative intent, in the Western healthcare region of Sweden. MATERIALS AND METHODS: In this prospective observational study, 311 HNC patients completed quality of life questionnaires for cancer (EORTC QLQ-C30 and EORTC QLQ-H&N35) and for older patients with cancer (EORT QLQ-ELD14) at diagnosis and 3, 6, and 12 months after start of treatment. Mean scores for patients ≥70 years old were compared to younger patients (50 to 69 years old) to assess differences in HRQOL. RESULTS: Of the 311 study participants, 105 patients were ≥70 years old (median age 76.7), of which 32 were ≥80 years of age. Most HRQOL scores were equal or better for older adult patients at 3 months after treatment, but physical function was better for younger adult patients up to 12 months after treatment. At 6 months the HRQOL was similar (older patients had less appetite loss and financial difficulties), while the oldest patients (≥80 years) had worse fatigue, role function, and feeling ill at 12 months. For the EORTC-ELD-14 questionnaire, older patients scored better for worries at diagnosis and reported more difficulties in maintaining purpose at 12 months after treatment. CONCLUSION: When curative treatment is administered, older adult patients with HNC have similar or even better HRQOL compared to younger adult patients, except for physical function, during the first year.

Avaliação da satisfação de pacientes oncológicos com o serviço de saúde em um hospital público no Brasil / Evaluation of oncology patients satisfaction with health service in a public hospital in Brazil

Resumo Introdução A satisfação dos pacientes é fundamental para melhorar a qualidade dos serviços. Para uniformizar as pesquisas foi criado o EORTC-IN-PATSAT32. Objetivo O objetivo foi avaliar a satisfação dos pacientes com a internação. Método Foram entrevistados 322 pacientes, através dos questionários socioeconômico e EORTC-IN-PATSAT32. Os itens múltiplos foram agrupados nas dimensões previstas na versão brasileira do questionário. Foram utilizados testes de hipóteses para avaliar diferenças na avaliação. Resultados A maioria dos pacientes era do sexo masculino, maiores de 60 anos, baixa escolaridade, casados, em atendimento clínico e sem metástase. Maior nível de satisfação foi com alta hospitalar e maior insatisfação com a estrutura. Houve maior satisfação com a equipe multiprofissional entre os pacientes com menor escolaridade e mais de 40 anos. Os pacientes cirúrgicos e brancos tiveram a maior satisfação com os médicos. Pacientes casados foram os mais satisfeitos com a conduta terapêutica, enquanto homens e idosos foram os mais satisfeitos com a estrutura, e os brancos mais satisfeitos com a alta. Conclusão Sexo, faixa etária, raça, grau de escolaridade, estado civil e modalidade de tratamento influenciam a satisfação dos pacientes. Recomenda-se o desenvolvimento de estudos em outros hospitais do país para relacionar a satisfação com as características da população brasileira.

Abstract Background Patient satisfaction is fundamental to improve the quality of health services. In order to standardize the surveys, the EORTC-IN-PATSAT32 questionnaire was created. Objective The objective was to evaluate patients' satisfaction with hospitalization. Method 322 patients were interviewed through the socioeconomic aspects and EORTC-IN-PATSAT32 questionnaires. The multiple items were grouped in the dimensions provided for in the Brazilian version of the questionnaire. Hypothesis tests were used to evaluate differences in the evaluation. Results The majority of the patients were male, older than 60 years, low educational level, married, in clinical care and without metastasis. Higher level of satisfaction was with hospital discharge and greater dissatisfaction with the structure. There was greater satisfaction with the multi-professional team among patients with less education and more than 40 years. Surgical and white patients had the greatest satisfaction with physicians. Married patients were the most satisfied with the therapeutic conduct, while men and elderly were the most satisfied with the structure, as long as whites were more satisfied with the discharge. Conclusion Patient satisfaction is influenced by gender, age, race, education level, marital status and treatment modality. It is recommended the development of studies in other hospitals in the country to relate the satisfaction with the characteristics of the Brazilian population.