Legacy and alternative per- and polyfluoroalkyl substances in the U.S. general population: Paired serum-urine data from the 2013-2014 National Health and Nutrition Examination Survey.

Concerns are heightened from detecting environmentally persistent man-made per- and polyfluoroalkyl substances (PFAS) in drinking water systems around the world. Many PFAS, including perfluorooctane sulfonate (PFOS) and perfluorooctanoate (PFOA), remain in the human body for years. Since 1999-2000, assessment of exposure to PFOS, PFOA, and other select PFAS in the U.S. general population has relied on measuring PFAS serum concentrations in participants of the National Health and Nutrition Examination Survey (NHANES). Manufacturers have replaced select chemistries ("legacy" PFAS) with PFAS with shorter biological half-lives (e.g., GenX, perfluorobutanoate [PFBA]) which may efficiently eliminate in urine. However, knowledge regarding exposure to these compounds is limited. We analyzed 2682 urine samples for 17 legacy and alternative PFAS in 2013-2014 NHANES participants ≥6 years of age. Concentrations of some of these PFAS, measured previously in paired serum samples from the same NHANES participants, suggested universal exposure to PFOS and PFOA, and infrequent or no exposure to two short-chain PFAS, perfluorobutane sulfonate and perfluoroheptanoate. Yet, in urine, PFAS were seldom detected; the frequency of not having detectable concentrations of any of the 17 PFAS was 67.5%. Only two were detected in >1.5% of the population: PFBA (13.3%) and perfluorohexanoate (PFHxA, 22.6%); the 90th percentile urine concentrations were 0.1 µg/L (PFBA), and 0.3 µg/L (PFHxA). These results suggest that exposures to short-chain PFAS are infrequent or at levels below those that would result in detectable concentrations in urine. As such, these findings do not support biomonitoring of short-chain PFAS or fluorinated alternatives in the general population using urine, and highlight the importance of selecting the adequate biomonitoring matrix.

[Malnutrition and inequalities in developmentalist Spain: rural food and nutrition surveys]. / Malnutrición y desigualdades en la España del desarrollismo: las encuestas rurales de alimentación y nutrición.

INTRODUCTION: the stage of autarky and early years of developmentalism was one of the periods in the contemporary history of Spain when inequalities in food and nutrition became more pronounced. OBJECTIVES: to examine malnutrition among the rural population (municipalities with fewer than 2000 inhabitants), including territorial inequalities and the delayed onset of a rural food and nutrition transition. METHODS: we analysed the rural food and nutrition surveys carried out by the General Commission for Supplies and Transport (Spanish initials: CAT) and the Food and Nutrition Education Programme (Spanish initials: EDALNU) between 1964 and 1972. RESULTS: the rural population presented a deficit of animal proteins, calcium and vitamins A and B2, due to scant consumption of protective foods. Andalucía and inland Spain were the regions with the highest percentage of people whose diet did not meet nutritional requirements. These deficiencies were not only responsible for the prevalence of caries and skin, mucous membrane and eye lesions, but were also behind delayed growth (height and weight). This was not the result so much of poverty as of the persistence of poor eating habits. CONCLUSIONS: besides evidencing the delayed onset of a food and nutritional transition in the Spanish rural population, our findings document policies that sought to encourage the consumption of protective foods in rural areas and empower the population with regard to food and nutrition.

Introducción: la etapa de la autarquía y los primeros años del desarrollismo fue uno de los periodos de la historia contemporánea de España en el que las desigualdades en materia alimentaria y nutricional se hicieron más evidentes.Objetivos: abordar la malnutrición que afectaba a la población rural (municipios de menos de 2000 habitantes), sus desigualdades territoriales y el retraso que mostraba su transición alimentaria y nutricional.Métodos: se han analizado las encuestas rurales de alimentación y nutrición que llevaron a cabo la Comisaría General de Abastecimientos y Transportes (CAT) y el Programa de Educación en Alimentación y Nutrición (Edalnu) entre 1964 y 1972.Resultados: la población rural mostraba un déficit de proteínas animales, de calcio, de vitamina A y de vitamina B2, justificado por el escaso consumo que realizaba de alimentos protectores. Andalucía y la España interior eran las regiones que mostraban mayores porcentajes de personas que no alcanzaban los requerimientos nutricionales. Dichas carencias, que explicaban la prevalencia de caries, así como de lesiones en la piel, en mucosas y oculares, también estaban detrás del retraso en la talla y el peso. No respondían tanto a la escasez de recursos económicos como a la persistencia de hábitos alimentarios inadecuados.Conclusiones: los resultados, además de mostrar el retraso de la población rural española en términos de transición alimentaria y nutricional, avalan las políticas que buscaban estimular en el ámbito rural el consumo de alimentos protectores y empoderar a la población en materia de alimentación y nutrición.

Historia de los métodos de valoración del consumo alimentario y aplicaciones / History of the valuation methods and applications of food consumption

Los métodos de valoración del consumo de alimentos, son utilizados para evaluar la salud nutricional de la población y sirven de base para la elaboración de guías, recomendaciones nutricionales y planes de salud, y el estudio de estos temas constituye una de las grandes tareas de la investigación y de las políticas sanitarias en los países desarrollados. Los principales avances en este área en nuestro país se han realizado a partir de 1940, avanzándose tanto en la fiabilidad de los datos, como en la estandarización de los estudios, lo que es una condición necesaria para poder comparar los cambios ocurridos a lo largo del tiempo. En este artículo se analizan la historia y aplicación de las diferentes encuestas dietéticas, de la historia dietética y de los Registros de frecuencia de alimentos. Demás de la información procedente de algunas encuestas realizadas a nivel nacional, los principales datos de que disponemos actualmente para planificación en salud publica Nutricional, proceden de la explotación nutricional de las encuestas de presupuestos familiares y de las hojas de balance alimentario, basadas en datos proporcionados por el Ministerio de Agricultura (AU)

The food consumption assessment methods are used in nutrition and health population surveys and are the basis for the development of guidelines, nutritional recommendations and health plans, The study of these issues is one of the major tasks of the research and health policy in developed countries. Major advances nationally in this area have been made since 1940, both in the reliability of the data and in the standardization of studies, which is a necessary condition to compare changes over time. In this article the history and application of different dietary surveys, dietary history and food frequency records are analyzed. Besides information from surveys conducted at a national level, the main data currently available for public health planning in nutrition comes from nutritional analysis of household budget surveys and food balance sheets, based on data provided by the Ministry of Agriculture (AU)

Blood cholesterol trends 2001-2011 in the United States: analysis of 105 million patient records.

OBJECTIVES: We report annual trends in low density lipoprotein cholesterol (LDL-C) from an in-care patient population of nearly 105 million adults across the United States (U.S.), from 2001 through 2011. BACKGROUND: Average blood cholesterol values have declined in the U.S. since at least 1960. The National Health and Nutrition Examination Survey (NHANES) reported declining blood cholesterol values from 1999 through 2010. In the absence of more recent published data, we examined LDL-C values from a single clinical laboratory database to determine whether these values continued to decline through 2011. METHODS AND RESULTS: We extracted almost 247 million LDL-C results from nearly 105 million adults who received diagnostic testing from a single national clinical laboratory. Annual age-adjusted mean LDL-C values were calculated, and analyzed by gender. Piecewise regression analysis of the total study population indicates a breakpoint, or change in slope, in the years following 2008 (F = 163.13; p<0.05). Between 2001 and 2008, the average rate of annual decline was -2.05 mg/dL (95% CI [-2.35, -1.75]). After 2008, mean LDL-C levels flattened out, with a slope not statistically different from zero (slope = -0.10 mg/dL/year; 95% CI [-1.46, 1.26]). This stabilization was observed in both genders and all age ranges, and was also reflected in the percentage of results in low- and high-risk categories. CONCLUSIONS: The trends reported suggest historical progress in decreasing LDL-C levels, observed from 2001-2008, may have stalled in recent years. Further research is needed to determine the cause of the observed trends and develop new strategies to reduce lipid-based cardiovascular risk further.

Revistas de Ciencias de la Nutrición en los países ibero latinoamericanos en el siglo XXI / Nutritional sciences journals in iberolatin american countries in the XXInt Century

La presencia de la nutrición como materia independiente dentro de los planes de estudio de las facultades de Medicina españolas ha sido exigua hasta el final del siglo XX. Pareja a esta carencia ha sido la falta de vehículos científicos solventes. A lo largo de los doce años transcurridos en el siglo XXI hemos asistido a un crecimiento importante en calidad y cantidad de las oportunidades especificas para las ciencias de la nutrición en lengua castellana y portuguesa. En 2000 aparecían en el Journal Citation Reports Science Edition 51 revistas en la categoría de Nutrition & Dietetics. Entre ellas solo había una ibero latinoamericana, Archivos Latinoamericanos de Nutrición (ALAN, ISSN 0004-0622). A lo largo del siglo XXI se han incorporado tres revistas ibero latinoamericanas al JCR, Nutrición Hospitalaria (Nutr Hosp, ISSN 0212-1611) en 2006, Revista de Nutricao (Rev Nutr, ISSN 1415-5273) y Revista Española de Nutrición Comunitaria (Rev Esp Nutr Comunit, ISSN 1135-3074) en 2007. Las cuatro revistas van teniendo un lugar cada dia mas destacado en otras plataformas electrónicas, prestando un servicio importante a la sociedad científica, no solo de su ámbito, sino en el resto del mundo. Aun cuando la lengua inglesa domina la comunicación científica, la masa crítica de publicaciones ya existentes en castellano y el ámbito de influencia de esta lengua es un estimulo para seguir utilizándola como vehículo científico (AU)

The presence of nutrition as an independent matter in the educational programs of the Spanish Faculties of Medicine has been scanty until the end of the XXth century. We have witnessed an important development of the specific opportunities for the nutritional sciences in terms of quality and quantity in the XXIst century. Only one ibero latin American journal , Archivos Latinoamericanos de Nutrición (ALAN, ISSN 0004-0622), was present in the Journal Citation Reports, Science Edition among the 51 journals under the heading of Nutrition & Dietetics. Three more ibero latin American journals have been incorporated to JCR in the XXIst century, Nutrición Hospitalaria (Nutr Hosp, ISSN 0212-1611) in 2006, Revista de Nutricao (Rev Nutr, ISSN 1415-5273) and Revista Española de Nutrición Comunitaria (Rev Esp Nutr Comunit, ISSN 1135-3074) in 2007. The four journals are having a growing importance in other electronic platforms, rendering an important service to the scientific society, not only in their environment, but also in the rest of the world. Although English language dominates scientific communications, the critical mass of already existing journals in Spanish and the area of influence of this language is a good stimulus for continuing its utilization (AU)

"Quicker and sicker" under Medicare's prospective payment system for hospitals: new evidence on an old issue from a national longitudinal survey.

Medicare's prospective payment system for hospitals (PPS), introduced in the USA in 1983, replaced cost reimbursement with a system of fixed rates which created incentives for hospitals to control costs. Previous studies found that elderly patients were discharged from hospital "quicker and sicker" under PPS and concluded that families were coping at home. We analyse a national longitudinal survey, the first National Health and Nutrition Examination Survey and its Epidemiologic Followup Study, which includes data on more outcomes over a longer period than earlier studies. We find that the rate of admission to nursing homes from the community in the first weeks after a hospital discharge more than tripled under PPS, suggesting that families were not always able to cope. As another response to sicker patients, discharges directly to nursing homes from hospitals, which jumped initially under PPS, may have risen further when payment rates were tightened in the early 1990s. Hospital readmissions fell after the first few years. Our findings are strengthened by the fact that we control for patients' health using health information collected independently of hospital admission.